Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?

[1]  Robert S Root-Bernstein,et al.  HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins. , 2005, Journal of theoretical biology.

[2]  K. Kosik,et al.  MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. , 2005, Cancer research.

[3]  N. Iwai,et al.  Polymorphisms in human pre-miRNAs. , 2005, Biochemical and biophysical research communications.

[4]  Kathryn A. O’Donnell,et al.  c-Myc-regulated microRNAs modulate E2F1 expression , 2005, Nature.

[5]  S. Lowe,et al.  A microRNA polycistron as a potential human oncogene , 2005, Nature.

[6]  H. Horvitz,et al.  MicroRNA expression profiles classify human cancers , 2005, Nature.

[7]  James M. Pipas,et al.  SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells , 2005, Nature.

[8]  W. Filipowicz,et al.  Post-transcriptional gene silencing by siRNAs and miRNAs. , 2005, Current opinion in structural biology.

[9]  M. Gleave,et al.  Antisense therapy for cancer , 2005, Nature Reviews Cancer.

[10]  P. Iversen,et al.  In vivo Bioavailability and Pharmacokinetics of a c-MYC Antisense Phosphorodiamidate Morpholino Oligomer, AVI-4126, in Solid Tumors , 2005, Clinical Cancer Research.

[11]  R. Shiekhattar,et al.  MicroRNA biogenesis and cancer. , 2005, Cancer research.

[12]  V. Kim.  MicroRNA biogenesis: coordinated cropping and dicing , 2005, Nature Reviews Molecular Cell Biology.

[13]  Kwang-Soo Kim,et al.  Depletion of Human Micro-RNA miR-125b Reveals That It Is Critical for the Proliferation of Differentiated Cells but Not for the Down-regulation of Putative Targets during Differentiation* , 2005, Journal of Biological Chemistry.

[14]  A. Saïb,et al.  A Cellular MicroRNA Mediates Antiviral Defense in Human Cells , 2005, Science.

[15]  Blossom Damania,et al.  Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Gunsalus,et al.  Combinatorial microRNA target predictions , 2005, Nature Genetics.

[17]  Y. Li,et al.  Incorporating structure to predict microRNA targets. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[18]  F. Slack,et al.  RAS Is Regulated by the let-7 MicroRNA Family , 2005, Cell.

[19]  M. Byrom,et al.  Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis , 2005, Nucleic acids research.

[20]  Y. Fujii,et al.  Regulation of human immunodeficiency virus 1 transcription by nef microRNA. , 2005, The Journal of general virology.

[21]  J. Castle,et al.  Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs , 2005, Nature.

[22]  C. Sander,et al.  Identification of microRNAs of the herpesvirus family , 2005, Nature Methods.

[23]  Guiliang Tang,et al.  siRNA and miRNA: an insight into RISCs. , 2005, Trends in biochemical sciences.

[24]  Jan Beal.  Silence is golden: can RNA interference therapeutics deliver? , 2005, Drug Discovery Today.

[25]  C. Burge,et al.  Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.

[26]  Michael Famulok,et al.  Intramers and Aptamers: Applications in Protein‐Function Analyses and Potential for Drug Screening , 2005, Chembiochem : a European journal of chemical biology.

[27]  De-Pei Liu,et al.  The role of small RNAs in human diseases: Potential troublemaker and therapeutic tools , 2005, Medicinal research reviews.

[28]  N. Saksena,et al.  HIV-1 nef suppression by virally encoded microRNA. , 2004, Retrovirology.

[29]  T. Tuschl,et al.  The Human DiGeorge Syndrome Critical Region Gene 8 and Its D. melanogaster Homolog Are Required for miRNA Biogenesis , 2004, Current Biology.

[30]  Ravi Jain,et al.  MicroRNA-143 Regulates Adipocyte Differentiation* , 2004, Journal of Biological Chemistry.

[31]  B. Cullen,et al.  Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. , 2004, RNA.

[32]  B. Cullen,et al.  Adenovirus VA1 Noncoding RNA Can Inhibit Small Interfering RNA and MicroRNA Biogenesis , 2004, Journal of Virology.

[33]  R. Shiekhattar,et al.  The Microprocessor complex mediates the genesis of microRNAs , 2004, Nature.

[34]  N. Rajewsky,et al.  A pancreatic islet-specific microRNA regulates insulin secretion , 2004, Nature.

[35]  F. Slack,et al.  The age of high-throughput microRNA profiling , 2004, Nature Methods.

[36]  P. Jin,et al.  RNA and microRNAs in fragile X mental retardation , 2004, Nature Cell Biology.

[37]  Sanghyuk Lee,et al.  MicroRNA genes are transcribed by RNA polymerase II , 2004, The EMBO journal.

[38]  Anton J. Enright,et al.  Human MicroRNA Targets , 2004, PLoS biology.

[39]  J. Wengel,et al.  LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA. , 2004, Biochemistry.

[40]  T. Tuschl,et al.  Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.

[41]  V. Ambros.  The functions of animal microRNAs , 2004, Nature.

[42]  Y. Yatabe,et al.  Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival , 2004, Cancer Research.

[43]  Anton J. Enright,et al.  Identification of Virus-Encoded MicroRNAs , 2004, Science.

[44]  D. Bartel,et al.  MicroRNA-Directed Cleavage of HOXB8 mRNA , 2004, Science.

[45]  Jonathan Hall,et al.  Potential applications of siRNA for pain therapy , 2004, Expert opinion on biological therapy.

[46]  C. Croce,et al.  Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Phillip D Zamore,et al.  Sequence-Specific Inhibition of Small RNA Function , 2004, PLoS biology.

[48]  Daniela C. Zarnescu,et al.  Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway , 2004, Nature Neuroscience.

[49]  Arndt Borkhardt,et al.  High expression of precursor microRNA‐155/BIC RNA in children with Burkitt lymphoma , 2004, Genes, chromosomes & cancer.

[50]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[51]  D. Bartel,et al.  MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.

[52]  U. Kutay,et al.  Nuclear Export of MicroRNA Precursors , 2004, Science.

[53]  B. Cullen,et al.  Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. , 2003, Genes & development.

[54]  G. Tortora,et al.  Clinical Studies in Patients with Solid Tumors using a Second‐Generation Antisense Oligonucleotide (GEM®231) Targeted against Protein Kinase A Type I , 2003, Annals of the New York Academy of Sciences.

[55]  Michael Z Michael,et al.  Reduced accumulation of specific microRNAs in colorectal neoplasia. , 2003, Molecular cancer research : MCR.

[56]  V. Kim,et al.  The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.

[57]  Martin Tabler,et al.  Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. , 2003, Nucleic acids research.

[58]  B. Cullen,et al.  MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[59]  Michael T. McManus,et al.  MicroRNAs and cancer. , 2003, Seminars in cancer biology.

[60]  R. Russell,et al.  bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila , 2003, Cell.

[61]  Frank Baas,et al.  UvA-DARE ( Digital Academic Repository ) In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid ( LNA ) antisense oligonucleotides , 2017 .

[62]  G. Dreyfuss,et al.  Numerous microRNPs in neuronal cells containing novel microRNAs. , 2003, RNA.

[63]  Alex Toftgaard Nielsen,et al.  Single nucleotide polymorphism genotyping using locked nucleic acid (LNA™) , 2003, Expert review of molecular diagnostics.

[64]  C. Croce,et al.  Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[65]  A. Caudy,et al.  Fragile X-related protein and VIG associate with the RNA interference machinery. , 2002, Genes & development.

[66]  M. Siomi,et al.  A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. , 2002, Genes & development.

[67]  Henning Urlaub,et al.  Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi , 2002, Cell.

[68]  V. Kim,et al.  MicroRNA maturation: stepwise processing and subcellular localization , 2002, The EMBO journal.

[69]  Douglas H. Turner,et al.  Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[70]  David R Corey,et al.  Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase. , 2002, Biochemistry.

[71]  W. S. Hayward,et al.  Avian bic, a Gene Isolated from a Common Retroviral Site in Avian Leukosis Virus-Induced Lymphomas That Encodes a Noncoding RNA, Cooperates with c-myc in Lymphomagenesis and Erythroleukemogenesis , 2002, Journal of Virology.

[72]  M. Mann,et al.  miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. , 2002, Genes & development.

[73]  A. Levin,et al.  Drug properties of second-generation antisense oligonucleotides: how do they measure up to their predecessors? , 2001, Current opinion in investigational drugs.

[74]  A. Pasquinelli,et al.  A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA , 2001, Science.

[75]  A. Caudy,et al.  Role for a bidentate ribonuclease in the initiation step of RNA interference , 2001 .

[76]  J. Karras,et al.  Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing. , 2000, Molecular pharmacology.

[77]  M. Knowles,et al.  Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene by Antisense Oligonucleotides* , 1999, The Journal of Biological Chemistry.

[78]  Stephan Wolf,et al.  Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma , 1998, Oncogene.

[79]  E. Lesnik,et al.  2′-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells* , 1997, The Journal of Biological Chemistry.

[80]  Pierre Martin.  A New Access to 2′‐O‐Alkylated Ribonucleosides and Properties of 2′‐O‐ Alkylated Oligoribonucleotides. , 1995 .

[81]  Pierre Martin,et al.  Ein neuer Zugang zu 2′‐O‐Alkylribonucleosiden und Eigenschaften deren Oligonucleotide , 1995 .

[82]  J. Pipas,et al.  SV 40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells , 2005 .

[83]  M. Manoharan,et al.  RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics. , 2005, Methods in enzymology.

[84]  Nóra Varga,et al.  Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. , 2004, Nucleic acids research.

[85]  Sam Griffiths-Jones,et al.  The microRNA Registry , 2004, Nucleic Acids Res..

[86]  A Rzhetsky,et al.  Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions. , 2000, Current topics in microbiology and immunology.

[87]  M. A. Rector,et al.  References and Notes Materials and Methods Som Text Fig. S1 Table S1 References a Microrna in a Multiple- Turnover Rnai Enzyme Complex , 2022 .