Biosensors for analytical microsystems

A modular concept for analytical microsystems with separately developed and optimized components is proposed, where parts can be easily substituted. Since the system should be universal hybrid integration is preferred over monolithic fabrication technology.The biosensor as an essential part of an analytical microsystem is commonly restricted in its functional stability due to the lifetime of the biological component and the adhesion of the sensitive layer at the transducer. Optimum design requirements have to be derived from the particular system to be measured. For the optimization of the (bio)sensor the polymer matrix carrying or covering the enzyme has been modified, the transducer design itself has been varied, and enzymes have been coupled.

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