Autoimmune ovarian disease: mechanism of disease induction and prevention.

[1]  B. Conrad,et al.  A Human Endogenous Retroviral Superantigen as Candidate Autoimmune Gene in Type I Diabetes , 1997, Cell.

[2]  Bernhard Hemmer,et al.  Identification of High Potency Microbial and Self Ligands for a Human Autoreactive Class II–restricted T Cell Clone , 1997, The Journal of experimental medicine.

[3]  Y. Hayashi,et al.  Identification of α-Fodrin as a Candidate Autoantigen in Primary Sjögren's Syndrome , 1997 .

[4]  J. Todd,et al.  Mapping of the IDDM Locus Idd3 to a 0.35-cM Interval Containing the Interleukin-2 Gene , 1997, Diabetes.

[5]  D. Mason,et al.  The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients , 1996, The Journal of experimental medicine.

[6]  P. Ohashi,et al.  T cell selection and autoimmunity: flexibility and tuning. , 1996, Current opinion in immunology.

[7]  E. Pearce,et al.  Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils , 1996, The Journal of experimental medicine.

[8]  J. McCluskey,et al.  Hierarchical self-tolerance to T cell determinants within the ubiquitous nuclear self-antigen La (SS-B) permits induction of systemic autoimmunity in normal mice , 1996, The Journal of experimental medicine.

[9]  M. Daly,et al.  Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[10]  M. Mamula,et al.  B7 costimulation and autoantigen specificity enable B cells to activate autoreactive T cells. , 1996, Journal of immunology.

[11]  J. Drago,et al.  Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile. , 1996, Development.

[12]  E. Shevach,et al.  Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells. , 1996, Journal of immunology.

[13]  S. Sakaguchi,et al.  Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation , 1996, The Journal of experimental medicine.

[14]  R. Caspi,et al.  Susceptibility to Murine Experimental Autoimmune Oophoritis Is Associated With Genes Outside the Major Histocompatibility Complex (MHC) , 1996, American journal of reproductive immunology.

[15]  D. Green,et al.  CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. , 1996, Immunity.

[16]  Toshitada Takahashi,et al.  Administration of anti‐interleukin‐2 receptor α antibody in vivo induces localized autoimmune disease , 1996, European journal of immunology.

[17]  C. Mohan,et al.  Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus , 1996, The Journal of experimental medicine.

[18]  John A Todd,et al.  Genetic Analysis of Autoimmune Disease , 1996, Cell.

[19]  A. B. Lyons,et al.  The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help , 1996, The Journal of experimental medicine.

[20]  K. Tung,et al.  Rapid induction of autoantibodies by endogenous ovarian antigens and activated T cells: implication in autoimmune disease pathogenesis and B cell tolerance. , 1996, Journal of immunology.

[21]  P. Linsley,et al.  The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells , 1996, Journal of Experimental Medicine.

[22]  P. Gleeson,et al.  Organ‐specific Autoimmunity Induced by Lymphopenia , 1996, Immunological reviews.

[23]  J. Lunceford,et al.  Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dysgenesis, co-localizes with Il2, Fgfb, and Idd3 , 1996, The Journal of experimental medicine.

[24]  K. Tung,et al.  Frequency of molecular mimicry among T cell peptides as the basis for autoimmune disease and autoantibody induction. , 1995, Journal of immunology.

[25]  P. Travers,et al.  Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[26]  K. Tung,et al.  Altered target organ. A mechanism of postrecovery resistance to murine autoimmune oophoritis. , 1995, Journal of immunology.

[27]  K. Tung,et al.  A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology. , 1995, Journal of immunology.

[28]  M. Toda,et al.  Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.

[29]  R. Gazzinelli,et al.  Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. , 1995, Current opinion in immunology.

[30]  W. Hickey,et al.  Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Rothbard,et al.  Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands. , 1995, Immunity.

[32]  J. Strominger,et al.  Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein , 1995, Cell.

[33]  J. Todd,et al.  Aod1, the immunoregulatory locus controlling abrogation of tolerance in neonatal thymectomy-induced autoimmune ovarian dysgenesis, maps to mouse chromosome 16. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[34]  J. Harley,et al.  Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity , 1995, The Journal of experimental medicine.

[35]  I. Gery,et al.  Autoimmunity in the eye and its regulation. , 1994, Current opinion in immunology.

[36]  M. Mamula,et al.  The expression of self antigenic determinants: implications for tolerance and autoimmunity. , 1994, Current opinion in immunology.

[37]  P. Linsley,et al.  Soluble CTLA-4 can suppress autoantibody production and elicit long term unresponsiveness in a novel transgenic model. , 1994, Journal of immunology.

[38]  A. Rosen,et al.  Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes , 1994, The Journal of experimental medicine.

[39]  P. A. Peterson,et al.  Induction of autoimmune disease in mice by germline alteration of the T cell receptor gene expression. , 1994, Journal of immunology.

[40]  K. Tung,et al.  T cell peptide of a self-protein elicits autoantibody to the protein antigen. Implications for specificity and pathogenetic role of antibody in autoimmunity. , 1993, Journal of immunology.

[41]  D. Hunt,et al.  Antigen mimicry in autoimmune disease sharing of amino acid residues critical for pathogenic T cell activation. , 1993, The Journal of clinical investigation.

[42]  J. Todd,et al.  Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[43]  D. Wraith,et al.  Cross-reactive antigen recognition by an encephalitogenic T cell receptor. Implications for T cell biology and autoimmunity. , 1992, Journal of immunology.

[44]  K. Tung,et al.  Tolerance mechanism in experimental ovarian and gastric autoimmune diseases. , 1992, Journal of immunology.

[45]  H. Mcdevitt,et al.  A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis , 1992, The Journal of experimental medicine.

[46]  Z. Halpern,et al.  Fecal carriage of Streptococcus bovis and inflammatory bowel disease. , 1992, Gastroenterology.

[47]  J. Dean,et al.  Biology of mammalian fertilization: role of the zona pellucida. , 1992, The Journal of clinical investigation.

[48]  K. Tung,et al.  Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. , 1991, Journal of immunology.

[49]  P. Gleeson,et al.  The parietal cell autoantibodies recognized in neonatal thymectomy-induced murine gastritis are the α and β subunits of the gastric proton pump , 1991 .

[50]  V. Singh,et al.  Molecular mimicry between uveitopathogenic site of retinal S-antigen and Escherichia coli protein: induction of experimental autoimmune uveitis and lymphocyte cross-reaction. , 1989, Cellular immunology.

[51]  M. Matsuyama,et al.  Development of multiple organ-localized autoimmune diseases in nude mice after reconstitution of T cell function by rat fetal thymus graft , 1986, The Journal of experimental medicine.

[52]  S. Sakaguchi,et al.  Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease , 1985, The Journal of experimental medicine.

[53]  A. Byskov Cell kinetic studies of follicular atresia in the mouse ovary. , 1974, Journal of reproduction and fertility.

[54]  W. Irvine,et al.  Spontaneous thyroiditis in thymectomized and irradiated Wistar rats. , 1973, Clinical and experimental immunology.

[55]  T. Sakakura,et al.  Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice , 1969, Science.

[56]  K. Tung,et al.  Neonatal injection of an ovarian peptide induces autoimmune ovarian disease in female mice: requirement of endogenous neonatal ovaries. , 1997, Immunity.

[57]  H. Macdonald,et al.  Superantigens of mouse mammary tumor virus. , 1995, Annual review of immunology.

[58]  K. Tung,et al.  Testicular and Ovarian Autoimmune Diseases , 1994 .

[59]  A. Coutinho,et al.  Autoimmunity : physiology and disease , 1993 .

[60]  J. Sudweeks Locus conteolling Bordetella perussis-induced histamine sensitization(Bphs), an autoimmune disease-susceptibility gene, chromosome 6 , 1993 .

[61]  K. Tung,et al.  Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida. , 1992, The Journal of clinical investigation.

[62]  I. Damjanov,et al.  Pathology of reproductive failure , 1991 .

[63]  Tung Ks,et al.  Immunologic basis of reproductive failure. , 1991 .