The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.

[1]  S. Soefje,et al.  Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy , 2015, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

[2]  S. J. Griffiths,et al.  p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells. , 2014, The Journal of clinical investigation.

[3]  A. Rudensky,et al.  Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection , 2014, The Journal of experimental medicine.

[4]  S. Jameson,et al.  Transcriptional downregulation of S1pr1 is required for establishment of resident memory CD8+ T cells , 2013, Nature Immunology.

[5]  Tom C Freeman,et al.  An expression atlas of human primary cells: inference of gene function from coexpression networks , 2013, BMC Genomics.

[6]  A. Kamphorst,et al.  Manipulating the PD-1 pathway to improve immunity. , 2013, Current opinion in immunology.

[7]  W. Heath,et al.  Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues. , 2013, Current opinion in immunology.

[8]  S. Orlow,et al.  IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis , 2013, The Journal of investigative dermatology.

[9]  Lei Jin,et al.  Immune Surveillance by CD8αα+ Skin Resident T Cells in Human Herpesvirus Infection , 2013, Nature.

[10]  Thomas Gebhardt,et al.  Memory T cell subsets, migration patterns, and tissue residence. , 2013, Annual review of immunology.

[11]  J. Schenkel,et al.  Sensing and alarm function of resident memory CD8+ T cells , 2013, Nature Immunology.

[12]  G. Ogg,et al.  Varicella Zoster–Specific CD4+Foxp3+ T Cells Accumulate after Cutaneous Antigen Challenge in Humans , 2013, The Journal of Immunology.

[13]  S. Bromley,et al.  Recirculating Memory T Cells Are a Unique Subset of CD4+ T Cells with a Distinct Phenotype and Migratory Pattern , 2013, The Journal of Immunology.

[14]  D. Lowy,et al.  Intravaginal immunization with HPV vectors induces tissue-resident CD8+ T cell responses. , 2012, The Journal of clinical investigation.

[15]  A. Osterhaus,et al.  Systemic varicella zoster virus reactive effector memory T‐cells impaired in the elderly and in kidney transplant recipients , 2012, Journal of medical virology.

[16]  H. Asada,et al.  A community-based survey of varicella-zoster virus-specific immune responses in the elderly. , 2012, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[17]  C. Chougnet,et al.  Homeostasis and function of regulatory T cells in aging. , 2012, Current opinion in immunology.

[18]  Alexandra Flemming Cancer: PD1 makes waves in anticancer immunotherapy , 2012, Nature reviews. Drug discovery.

[19]  C. Baecher-Allan,et al.  Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells. , 2012, Immunity.

[20]  Scott N. Mueller,et al.  Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation , 2012, Proceedings of the National Academy of Sciences.

[21]  R. Clark,et al.  Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity , 2012, Nature.

[22]  R. Clark,et al.  Skin Effector Memory T Cells Do Not Recirculate and Provide Immune Protection in Alemtuzumab-Treated CTCL Patients , 2012, Science Translational Medicine.

[23]  Thomas Gebhardt,et al.  Different patterns of peripheral migration by memory CD4+ and CD8+ T cells , 2011, Nature.

[24]  L. Battistini,et al.  Reversible Senescence in Human CD4+CD45RA+CD27− Memory T Cells , 2011, The Journal of Immunology.

[25]  A. Akbar,et al.  Immune responses in the skin in old age. , 2011, Current opinion in immunology.

[26]  E John Wherry,et al.  T cell exhaustion , 2011 .

[27]  A. Bowcock,et al.  Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities. , 2011, The Journal of allergy and clinical immunology.

[28]  Sarah E. Jackson,et al.  Cytomegalovirus infection induces the accumulation of short‐lived, multifunctional CD4+ CD45RA+ CD27− T cells: the potential involvement of interleukin‐7 in this process , 2011, Immunology.

[29]  K. Rosenthal,et al.  Intravaginal infection with herpes simplex virus type-2 (HSV-2) generates a functional effector memory T cell population that persists in the murine genital tract. , 2010, Journal of reproductive immunology.

[30]  J. Curnow,et al.  Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4(+) T cells during ageing , 2010 .

[31]  M. Levin,et al.  Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses. , 2010, The Journal of infectious diseases.

[32]  R. Webby,et al.  Dynamic T cell migration program provides resident memory within intestinal epithelium , 2010, The Journal of experimental medicine.

[33]  R. Clark Skin-resident T cells: the ups and downs of on site immunity. , 2010, The Journal of investigative dermatology.

[34]  M. Levin,et al.  VZV T cell-mediated immunity. , 2010, Current topics in microbiology and immunology.

[35]  K. Schmader,et al.  Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine. , 2009, The Journal of infectious diseases.

[36]  M. Salmon,et al.  Decreased TNF-α synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging , 2009, The Journal of experimental medicine.

[37]  Thomas Gebhardt,et al.  Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus , 2009, Nature Immunology.

[38]  F. Ginhoux,et al.  Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation , 2009, The Journal of experimental medicine.

[39]  Lisa C. Zaba,et al.  Resident and "inflammatory" dendritic cells in human skin. , 2009, The Journal of investigative dermatology.

[40]  N. J. Eungdamrong,et al.  Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. , 2009, The Journal of investigative dermatology.

[41]  M. Salmon,et al.  The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo. , 2008, The Journal of clinical investigation.

[42]  Y. Belkaid,et al.  Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation1 , 2008, The Journal of Immunology.

[43]  M. Irwin,et al.  Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine. , 2008, The Journal of infectious diseases.

[44]  L. Jones,et al.  Phenotypic analysis of human CD4+ T cells specific for immediate early 63 protein of varicella‐zoster virus , 2007, European journal of immunology.

[45]  M. Levin,et al.  Phenotypic and functional characterization of ex vivo T cell responses to the live attenuated herpes zoster vaccine. , 2007, Vaccine.

[46]  Stijn van Dongen,et al.  Construction, Visualisation, and Clustering of Transcription Networks from Microarray Expression Data , 2007, PLoS Comput. Biol..

[47]  R. Steinman,et al.  Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages. , 2007, The Journal of clinical investigation.

[48]  Bernard Roizman,et al.  Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis , 2007 .

[49]  A. Akbar,et al.  Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo , 2006 .

[50]  R. Clark,et al.  Response to Comment on “The Vast Majority of CLA+ T Cells Are Resident in Normal Skin” , 2006, The Journal of Immunology.

[51]  A. Akbar,et al.  Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo. , 2006, The Journal of clinical investigation.

[52]  P. Moss,et al.  The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age , 2005, Clinical and experimental immunology.

[53]  Mayte Suárez-Fariñas,et al.  "Harshlighting" small blemishes on microarrays , 2005, BMC Bioinformatics.

[54]  Zhijin Wu,et al.  Preprocessing of oligonucleotide array data , 2004, Nature Biotechnology.

[55]  A. Hayward,et al.  Lymphocyte responses to varicella zoster virus in the elderly , 1987, Journal of Clinical Immunology.

[56]  M. Levin,et al.  Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine. , 2003, The Journal of infectious diseases.

[57]  A. Arvin Varicella-zoster virus: molecular virology and virus-host interactions. , 2001, Current opinion in microbiology.

[58]  C. Franceschi,et al.  Inflamm‐aging: An Evolutionary Perspective on Immunosenescence , 2000 .

[59]  V. Maino,et al.  Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression. , 2000, The Journal of infectious diseases.

[60]  J. Altman,et al.  Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function , 1998, The Journal of experimental medicine.

[61]  D. Goldblatt The immunology of chickenpox. A review prepared for the UK Advisory Group on Chickenpox on behalf of the British Society for the Study of Infection. , 1998, The Journal of infection.

[62]  S. Walters,et al.  Chickenpox in childhood. A review prepared for the UK Advisory Group on Chickenpox on behalf of the British Society for the Study of Infection. , 1998, The Journal of infection.

[63]  A. Arvin,et al.  Varicella-zoster virus , 1996, Clinical microbiology reviews.

[64]  A. Haski Varicella‐zoster vaccine , 1994, The Medical journal of Australia.

[65]  A. G. M. Weddell,et al.  Dendritic Cells of Human Skin , 1969 .