Glass-forming tendency in the system water-dimethyl sulfoxide.

The glass-forming tendency on cooling and the stability of the wholly amorphous state on warming have been previously reported for many cryoprotective solutions. However, unlike the other solutions, those of dimethyl sulfoxide (Me(2)SO) have not been studied on cooling. In this paper, the glass-forming tendency of Me(2)SO aqueous solutions has been measured for solutions containing 40, 43, 45, and 47.5% (w/w) Me(2)SO. At a concentration of 45% (w/w), the glass-forming tendency decreases in the following order: levo-2, 3-butanediol, 1,3-butanediol, 1,2-propanediol, 1,2,3-butanetriol, dimethyl sulfoxide, dimethylformamide, diethylformamide, 1, 4-butanediol, ethylene glycol, glycerol, 1,3-propanediol. New measurements have also been made on warming the Me(2)SO solutions.

[1]  J. Mazuer,et al.  Critical cooling and warming rates to avoid ice crystallization in small pieces of mammalian organs permeated with cryoprotective agents. , 1996, Cryobiology.

[2]  P. Boutron,et al.  Stability of the amorphous state in the system water--1,2-propanediol. , 1979, Cryobiology.

[3]  D. Rasmussen,et al.  Phase Diagram for the System Water–Dimethylsulphoxide , 1968, Nature.

[4]  P. Mehl,et al.  Glass-forming tendency and stability of the amorphous state in the aqueous solutions of linear polyalcohols with four carbons. I. Binary systems water-polyalcohol. , 1986, Cryobiology.

[5]  P. Boutron.  Levo- and dextro-2,3-Butanediol and their racemic mixture: Very efficient solutes for vitrification , 1990 .

[6]  P. Boutron,et al.  Stability of the amorphous state in the system water--glycerol--dimethylsulfoxide. , 1978, Cryobiology.

[7]  N. Van Dang,et al.  Maximum in the stability of the amorphous state in the system water--glycerol--ethanol. , 1979, Cryobiology.

[8]  A. M. Karow.  The biophysics of organ cryopreservation , 1987 .

[9]  P. Boutron.  Comparison with the theory of the kinetics and extent of ice crystallization and of the glass-forming tendency in aqueous cryoprotective solutions. , 1986, Cryobiology.

[10]  R. L. Sutton.  Critical cooling rates to avoid ice crystallization in solutions of cryoprotective agents , 1991 .

[11]  Hey,et al.  Crystallization of Ice in Aqueous Solutions of Glycerol and Dimethyl Sulfoxide. 1. A Comparison of Mechanisms , 1996, Cryobiology.

[12]  Baudot,et al.  Glass-forming tendency and stability of aqueous solutions of diethylformamide and dimethylformamide , 1998, Cryobiology.

[13]  S. Murthy,et al.  Some insight into the physical basis of the cryoprotective action of dimethyl sulfoxide and ethylene glycol. , 1998, Cryobiology.

[14]  P. Mehl,et al.  Glass-forming tendency and stability of the amorphous state in the aqueous solutions of linear polyalcohols with four carbons: II. Ternary systems with water, 1,2-propanediol or 1,3-butanediol or 2,3-butanediol , 1987 .

[15]  P. Boutron,et al.  Stability of the amorphous state in the system water-glycerol-ethylene glycol. , 1979, Cryobiology.

[16]  P. Boutron.  Glass-Forming Tendency and Stability of the Amorphous State in Solutions of a 2,3-Butanediol Containing Mainly the Levo and Dextro Isomers in Water, Buffer, and Euro-Collins , 1993 .

[17]  P. Mehl,et al.  Theoretical prediction of devitrification tendency: determination of critical warming rates without using finite expansions. , 1990, Cryobiology.

[18]  C. Körber,et al.  Ternary systems with 1,2-propanediol-a new gain in the stability of the amorphous state in the system water-1,2-propanediol-1-propanol. , 1982, Cryobiology.

[19]  Odin,et al.  Effect of Saccharides on the Glass-Forming Tendency and Stability of Solutions of 2,3-Butanediol, 1,2-Propanediol, or 1,3-Butanediol in Water, Phosphate-Buffered Saline, Euro-Collins Solution, or Saint Thomas Cardioplegic Solution , 1996, Cryobiology.

[20]  P. Boutron.  More accurate determination of the quantity of ice crystallized at low cooling rates in the glycerol and 1,2-propanediol aqueous solutions: comparison with equilibrium. , 1984, Cryobiology.

[21]  P. Boutron,et al.  Stability of the amorphous state in the system water-1, 2-propanediol-1,3-propanediol , 1980 .

[22]  D. Macfarlane,et al.  Crystallization of ice in aqueous solutions of glycerol and dimethyl sulfoxide 2: ice crystal growth kinetics. , 1998, Cryobiology.