University of Dundee Loss of ubiquitin E 2 Ube 2 w rescues hypersensitivity of Rnf 4 mutant cells to DNA damage
暂无分享,去创建一个
[1] H. Paulson,et al. Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems* , 2015, The Journal of Biological Chemistry.
[2] W. Liu,et al. Biochemical and structural characterization of a novel ubiquitin-conjugating enzyme E2 from Agrocybe aegeria reveals Ube2w family-specific properties , 2015, Scientific Reports.
[3] Matylda Sczaniecka-Clift,et al. Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair , 2015, Nature Cell Biology.
[4] S. Gabriel,et al. A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination. , 2015, Molecular cell.
[5] W. Sundquist,et al. TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription , 2015, The EMBO journal.
[6] J. Garber,et al. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. , 2015, The Journal of clinical investigation.
[7] Stephen P. Jackson,et al. Ubiquitylation, neddylation and the DNA damage response , 2015, Open Biology.
[8] Chunaram Choudhary,et al. Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage , 2015, Molecular cell.
[9] David Baker,et al. Intrinsic disorder drives N-terminal ubiquitination by Ube2w , 2014, Nature chemical biology.
[10] D. Schindler,et al. Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia , 2014, Journal of Cell Science.
[11] N. Curtin. PARP inhibitors for anticancer therapy. , 2014, Biochemical Society transactions.
[12] M. Bétermier,et al. Is Non-Homologous End-Joining Really an Inherently Error-Prone Process? , 2014, PLoS genetics.
[13] C. Chiang,et al. Sumoylation in gene regulation, human disease, and therapeutic action , 2013, F1000prime reports.
[14] A. Sartori,et al. Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy. , 2013, Swiss medical weekly.
[15] H. Paulson,et al. The Ubiquitin-conjugating Enzyme (E2) Ube2w Ubiquitinates the N Terminus of Substrates* , 2013, The Journal of Biological Chemistry.
[16] M. Tatham,et al. Ube2W conjugates ubiquitin to α-amino groups of protein N-termini , 2013, The Biochemical journal.
[17] D. Durocher,et al. Regulation of DNA damage responses by ubiquitin and SUMO. , 2013, Molecular cell.
[18] James E. DiCarlo,et al. RNA-Guided Human Genome Engineering via Cas9 , 2013, Science.
[19] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[20] A. D’Andrea,et al. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. , 2012, Genes & development.
[21] S. Jackson,et al. RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. , 2012, Genes & development.
[22] R. Hay,et al. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. , 2012, Genes & development.
[23] Xiaolan Zhao,et al. Extensive DNA damage-induced sumoylation contributes to replication and repair and acts in addition to the mec1 checkpoint. , 2012, Molecular cell.
[24] Zekun Guo,et al. UBE2W interacts with FANCL and regulates the monoubiquitination of fanconi anemia protein FANCD2 , 2011, Molecules and cells.
[25] R. Hakem,et al. DNA double-strand break signaling and human disorders , 2010, Genome Integrity.
[26] Junya Chen,et al. FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair , 2010, Science.
[27] Z. Hořejší,et al. Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. , 2010, Molecular cell.
[28] M. Hengartner,et al. Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents , 2010, Cell.
[29] Kay Hofmann,et al. Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2 , 2010, Cell.
[30] J Wade Harper,et al. A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair. , 2010, Molecular cell.
[31] M. Sivasubramaniam,et al. Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway , 2010, Science.
[32] H. Brauch,et al. Polymorphisms in the UBC9 and PIAS3 genes of the SUMO-conjugating system and breast cancer risk , 2010, Breast Cancer Research and Treatment.
[33] S. Jackson,et al. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks , 2009, Nature.
[34] Melanie Keppler,et al. The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress , 2009, Nature.
[35] Ronald T. Hay,et al. An additional role for SUMO in ubiquitin-mediated proteolysis , 2009, Nature Reviews Molecular Cell Biology.
[36] M. Babu,et al. Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. , 2008, Molecular cell.
[37] M. Tatham,et al. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation , 2008, Nature Cell Biology.
[38] Anindya Dutta,et al. UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination , 2007, Molecular and Cellular Biology.
[39] P. Brzovic,et al. E2–BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages , 2007, Nature Structural &Molecular Biology.
[40] Hans Joenje,et al. Fanconi anemia and DNA replication repair. , 2007, DNA repair.
[41] Anindya Dutta,et al. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. , 2006, Molecular cell.
[42] Hee June Choi,et al. Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis , 2006, Nature Cell Biology.
[43] C. Ji,et al. Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana UBC-16 gene product. , 2006, Frontiers in bioscience : a journal and virtual library.
[44] J. Hoeijmakers,et al. Fanconi Anemia (Cross)linked to DNA Repair , 2005, Cell.
[45] J. Pereira-Leal,et al. The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway , 2005, Nature Structural &Molecular Biology.
[46] K. J. Patel,et al. The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair. , 2004, Molecular cell.
[47] C. Rogers,et al. Helicases involved in the repair of DNA inter-strand crosslinks , 2014 .