Chitosan-based formulations for delivery of DNA and siRNA.

[1]  S. Aiba Studies on chitosan: 2. Solution stability and reactivity of partially N-acetylated chitosan derivatives in aqueous media. , 1989, International journal of biological macromolecules.

[2]  T. Chandy,et al.  Chitosan--as a biomaterial. , 1990, Biomaterials, artificial cells, and artificial organs.

[3]  S. Aiba Studies on chitosan: 4. Lysozymic hydrolysis of partially N-acetylated chitosans. , 1992, International journal of biological macromolecules.

[4]  David John Adams,et al.  Chitinase activity in human serum and leukocytes , 1995, Infection and immunity.

[5]  R. Mumper,et al.  Novel polymeric condensing carriers for gene delivery , 1995 .

[6]  J. Kreuter,et al.  Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs , 1996 .

[7]  C. P. Sharma,et al.  Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. , 1997, Journal of biomedical materials research.

[8]  J. Ruysschaert,et al.  The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids , 1997, FEBS letters.

[9]  H. Kaş Chitosan: properties, preparations and application to microparticulate systems. , 1997, Journal of microencapsulation.

[10]  J. Lowe,et al.  Chitosan as a nasal delivery system: the effect of chitosan solutions on in vitro and in vivo mucociliary transport rates in human turbinates and volunteers. , 1997, Journal of pharmaceutical sciences.

[11]  R. Mumper,et al.  Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. , 1998, Journal of controlled release : official journal of the Controlled Release Society.

[12]  I. Kwon,et al.  Preparation of chitosan self-aggregates as a gene delivery system. , 1998, Journal of controlled release : official journal of the Controlled Release Society.

[13]  E. Wagner,et al.  Effects of membrane-active agents in gene delivery. , 1998, Journal of controlled release : official journal of the Controlled Release Society.

[14]  D A Lauffenburger,et al.  Optimization of Cell Surface Binding Enhances Efficiency and Specificity of Molecular Conjugate Gene Delivery* , 1998, The Journal of Biological Chemistry.

[15]  M. Wolfert,et al.  Chloroquine and amphipathic peptide helices show synergistic transfection in vitro , 1998, Gene Therapy.

[16]  A. Urtti,et al.  Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. , 1999, Biochimica et biophysica acta.

[17]  Krishnendu Roy,et al.  Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy , 1999, Nature Medicine.

[18]  R. Lockey,et al.  Intranasal IFN-γ gene transfer protects BALB/c mice against respiratory syncytial virus infection , 1999 .

[19]  Wagner,et al.  Application of membrane-active peptides for nonviral gene delivery. , 1999, Advanced drug delivery reviews.

[20]  L. Barrett,et al.  Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery , 1999, Gene Therapy.

[21]  Y. Machida,et al.  Biodegradation and distribution of water-soluble chitosan in mice. , 1999, Biomaterials.

[22]  C. Cho,et al.  Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[23]  S. W. Kim,et al.  pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer. , 2000, Bioconjugate chemistry.

[24]  T. Okano,et al.  Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[25]  Thomas de Quincey [C] , 2000, The Works of Thomas De Quincey, Vol. 1: Writings, 1799–1820.

[26]  Leaf Huang,et al.  Nonviral gene therapy: promises and challenges , 2000, Gene Therapy.

[27]  C. Cho,et al.  Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[28]  K. Yao,et al.  Formation of a DNA/N-dodecylated chitosan complex and salt-induced gene delivery , 2001 .

[29]  P. Artursson,et al.  Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo , 2001, Gene Therapy.

[30]  Y Wang,et al.  Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[31]  G. Borchard Chitosans for gene delivery. , 2001, Advanced drug delivery reviews.

[32]  Y. Okahata,et al.  Mechanism of cell transfection with plasmid/chitosan complexes. , 2001, Biochimica et biophysica acta.

[33]  K. Leong,et al.  Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH. , 2001, Biomacromolecules.

[34]  Y. Okahata,et al.  In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. , 2001, Biomaterials.

[35]  H E Junginger,et al.  Chitosan and its derivatives in mucosal drug and vaccine delivery. , 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[36]  I. Kwon,et al.  Structural characteristics of size-controlled self-aggregates of deoxycholic acid-modified chitosan and their application as a DNA delivery carrier. , 2001, Bioconjugate chemistry.

[37]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[38]  Tae Gwan Park,et al.  PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[39]  S. Neau,et al.  In vitro degradation of chitosan by bacterial enzymes from rat cecal and colonic contents. , 2002, Biomaterials.

[40]  K. Zhu,et al.  The influence of multivalent phosphate structure on the properties of ionically cross-linked chitosan films for controlled drug release. , 2002, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[41]  Clive J Roberts,et al.  Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. , 2002, Bioconjugate chemistry.

[42]  Mark E. Davis,et al.  Non-viral gene delivery systems. , 2002, Current opinion in biotechnology.

[43]  K. De Yao,et al.  Chitosan and its derivatives--a promising non-viral vector for gene transfection. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[44]  H. Junginger,et al.  Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. , 2002, Biomaterials.

[45]  장윤희,et al.  Y. , 2003, Industrial and Labor Relations Terms.

[46]  J. Nah,et al.  Efficient gene delivery by urocanic acid-modified chitosan. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[47]  D. Dykxhoorn,et al.  Killing the messenger: short RNAs that silence gene expression , 2003, Nature Reviews Molecular Cell Biology.

[48]  S. Davis,et al.  Nasal delivery of chitosan-DNA plasmid expressing epitopes of respiratory syncytial virus (RSV) induces protective CTL responses in BALB/c mice. , 2003, Vaccine.

[49]  A. ADoefaa,et al.  ? ? ? ? f ? ? ? ? ? , 2003 .

[50]  K. Romøren,et al.  The influence of formulation variables on in vitro transfection efficiency and physicochemical properties of chitosan-based polyplexes. , 2003, International journal of pharmaceutics.

[51]  J. Zia,et al.  Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles. , 2003, The Biochemical journal.

[52]  Zhi Ding,et al.  Galactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting. , 2003, International journal of pharmaceutics.

[53]  A. Urtti,et al.  Extracellular and intracellular barriers in non-viral gene delivery. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[54]  G. Guo,et al.  N-alkylated chitosan as a potential nonviral vector for gene transfection. , 2003, Bioconjugate chemistry.

[55]  C. Cho,et al.  Galactosylated chitosan (GC)-graft-poly(vinyl pyrrolidone) (PVP) as hepatocyte-targeting DNA carrier. Preparation and physicochemical characterization of GC-graft-PVP/DNA complex (1). , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[56]  P. Artursson,et al.  Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo , 2003, The journal of gene medicine.

[57]  D. Fischer,et al.  Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice. , 2004, Drug metabolism and disposition: the biological fate of chemicals.

[58]  K. Leong,et al.  The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. , 2004, Biomaterials.

[59]  K. Morris,et al.  Small Interfering RNA-Induced Transcriptional Gene Silencing in Human Cells , 2004, Science.

[60]  S. W. Kim,et al.  Polyethylene Glycol-Conjugated Copolymers for Plasmid DNA Delivery , 2004, Pharmaceutical Research.

[61]  J. Fernandes,et al.  Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[62]  T. Bettinger,et al.  Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability , 1998, Pharmaceutical Research.

[63]  A. Hoffman,et al.  Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression , 2004, Journal of biomaterials science. Polymer edition.

[64]  A. Aigner,et al.  Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[65]  D. Fischer,et al.  The Structure of PEG-Modified Poly(Ethylene Imines) Influences Biodistribution and Pharmacokinetics of Their Complexes with NF-κB Decoy in Mice , 2002, Pharmaceutical Research.

[66]  A. Urtti,et al.  Vitreous Is a Barrier in Nonviral Gene Transfer by Cationic Lipids and Polymers , 2003, Pharmaceutical Research.

[67]  Mark E. Davis,et al.  Lack of interferon response in animals to naked siRNAs , 2004, Nature Biotechnology.

[68]  J. Nah,et al.  Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. , 2004, Biomaterials.

[69]  Gerrit Borchard,et al.  Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis. , 2004, Vaccine.

[70]  Stefaan C. De Smedt,et al.  Cationic Polymer Based Gene Delivery Systems , 2000, Pharmaceutical Research.

[71]  F. Szoka,et al.  GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. , 2004, Advanced drug delivery reviews.

[72]  P. Artursson,et al.  Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers , 2004, Gene Therapy.

[73]  T. Kissel,et al.  Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. , 2005, Biomaterials.

[74]  K. Vårum,et al.  Influence of chitosan structure on the formation and stability of DNA-chitosan polyelectrolyte complexes. , 2005, Biomacromolecules.

[75]  Xin Yu Wang,et al.  Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[76]  W. Ahn,et al.  The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer. , 2005, Biomaterials.

[77]  S. Strand,et al.  Glycosaminoglycan destabilization of DNA-chitosan polyplexes for gene delivery depends on chitosan chain length and GAG properties. , 2005, Biochimica et biophysica acta.

[78]  Hong Yang,et al.  Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene , 2005, Nature Medicine.

[79]  C. Fong,et al.  Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[80]  J. Nah,et al.  Deoxycholic acid-conjugated chitosan oligosaccharide nanoparticles for efficient gene carrier. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[81]  H. Okamoto,et al.  Stability of chitosan-pDNA complex powder prepared by supercritical carbon dioxide process. , 2005, International journal of pharmaceutics.

[82]  Junfeng Zhang,et al.  Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector. , 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[83]  M. Sioud On the delivery of small interfering RNAs into mammalian cells , 2005, Expert opinion on drug delivery.

[84]  H. Lipps,et al.  Towards safe, non-viral therapeutic gene expression in humans , 2005, Nature Reviews Genetics.

[85]  K. Luk,et al.  An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes. , 2005, Biomaterials.

[86]  G. Guo,et al.  A thermoresponsive chitosan-NIPAAm/vinyl laurate copolymer vector for gene transfection. , 2005, Bioconjugate chemistry.

[87]  C. Cho,et al.  Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[88]  Daniel W. Pack,et al.  Design and development of polymers for gene delivery , 2005, Nature Reviews Drug Discovery.

[89]  A. Rolland Gene medicines: the end of the beginning? , 2005, Advanced drug delivery reviews.

[90]  H. Yoo,et al.  Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[91]  T. Delair,et al.  Poly(d,l-lactic acid) and chitosan complexes: interactions with plasmid DNA , 2005 .

[92]  D. Fischer,et al.  Uptake and Transport of PEG-Graft-Trimethyl-Chitosan Copolymer–Insulin Nanocomplexes by Epithelial Cells , 2005, Pharmaceutical Research.

[93]  Kwang Dong Kim,et al.  Targeted therapy of DNA tumor virus-associated cancers using virus-activated transcription factors. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

[94]  E. Kumacheva,et al.  Design of biocompatible chitosan microgels for targeted pH-mediated intracellular release of cancer therapeutics. , 2006, Biomacromolecules.

[95]  Chang-long Yu,et al.  Transfection of primary chondrocytes using chitosan-pEGFP nanoparticles. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[96]  Haliza Katas,et al.  Development and characterisation of chitosan nanoparticles for siRNA delivery. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[97]  K. Leong,et al.  PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. , 2006, Bioconjugate chemistry.

[98]  T. Kissel,et al.  Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes. , 2006, Bioconjugate chemistry.

[99]  P. Opolon,et al.  Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer. , 2006, Human gene therapy.

[100]  S. Zeng,et al.  A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. , 2006, International journal of pharmaceutics.

[101]  J. Nah,et al.  Receptor-mediated gene delivery into antigen presenting cells using mannosylated chitosan/DNA nanoparticles. , 2006, Journal of nanoscience and nanotechnology.

[102]  R. Lockey,et al.  Thiolated Chitosan/DNA Nanocomplexes Exhibit Enhanced and Sustained Gene Delivery , 2006, Pharmaceutical Research.

[103]  U. Guliyeva,et al.  Chitosan microparticles containing plasmid DNA as potential oral gene delivery system. , 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[104]  Kenneth A Howard,et al.  RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

[105]  Maryam Tabrizian,et al.  Effects of alginate inclusion on the vector properties of chitosan-based nanoparticles. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[106]  Jiyoung M Dang,et al.  Natural polymers for gene delivery and tissue engineering. , 2006, Advanced drug delivery reviews.

[107]  S. Shinkai,et al.  6-Amino-6-deoxy-chitosan. Sequential chemical modifications at the C-6 positions of N-phthaloyl-chitosan and evaluation as a gene carrier. , 2006, Carbohydrate research.

[108]  Q. Shi,et al.  Characterization of folate-chitosan-DNA nanoparticles for gene therapy. , 2006, Biomaterials.

[109]  M. Buschmann,et al.  High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. , 2006, Biomaterials.

[110]  K. Leong,et al.  Chitosan‐g‐PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions , 2006, The journal of gene medicine.

[111]  I. Bravo-Osuna,et al.  Development and in vitro evaluation of a thiomer-based nanoparticulate gene delivery system. , 2007, Biomaterials.

[112]  Tae Gwan Park,et al.  Molecular design of functional polymers for gene therapy , 2007 .

[113]  M. Kurisawa,et al.  Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery. , 2007, Biomaterials.

[114]  J. Nah,et al.  Chemical modification of chitosan as a gene carrier in vitro and in vivo , 2007 .

[115]  Claus-Michael Lehr,et al.  Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides. , 2007, Nanomedicine : nanotechnology, biology, and medicine.

[116]  Shubiao Zhang,et al.  Cationic lipids and polymers mediated vectors for delivery of siRNA. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[117]  K. Braeckmans,et al.  Nucleic acid delivery: Where material sciences and bio-sciences meet , 2007 .

[118]  Zhiyuan Hu,et al.  A novel PEGylation of chitosan nanoparticles for gene delivery , 2007, Biotechnology and applied biochemistry.

[119]  Jia-cong Shen,et al.  The gene transfection efficiency of thermoresponsive N,N,N-trimethyl chitosan chloride-g-poly(N-isopropylacrylamide) copolymer. , 2007, Biomaterials.

[120]  J. Kjems,et al.  The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. , 2007, Biomaterials.

[121]  A. Clarke,et al.  Gene manipulation through the use of small interfering RNA (siRNA): from in vitro to in vivo applications. , 2007, Advanced drug delivery reviews.

[122]  Yan Li,et al.  Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration: results of an in vitro and in vivo study. , 2007, Life sciences.

[123]  J. Kjems,et al.  Direct force measurements between siRNA and chitosan molecules using force spectroscopy. , 2007, Biophysical journal.

[124]  Lai Yeng Lee,et al.  PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: new carriers for DNA delivery. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[125]  Juan Yu,et al.  Chitosan microspheres as candidate plasmid vaccine carrier for oral immunisation of Japanese flounder (Paralichthys olivaceus). , 2008, Veterinary immunology and immunopathology.

[126]  P. Opanasopit,et al.  Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cells. , 2008, International journal of pharmaceutics.

[127]  Shirui Mao,et al.  Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[128]  Xian‐Zheng Zhang,et al.  Low molecular weight polyethylenimine grafted N-maleated chitosan for gene delivery: properties and in vitro transfection studies. , 2008, Biomacromolecules.

[129]  O. Alpar,et al.  Non-viral dried powders for respiratory gene delivery prepared by cationic and chitosan loaded liposomes. , 2008, International journal of pharmaceutics.

[130]  J. Nah,et al.  Galactosylated poly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[131]  Mehrdad Hamidi,et al.  Hydrogel nanoparticles in drug delivery. , 2008, Advanced drug delivery reviews.

[132]  Y. Kawashima,et al.  Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery. , 2008, International journal of pharmaceutics.

[133]  P. Opanasopit,et al.  Methylated N-(4-pyridinylmethyl) chitosan as a novel effective safe gene carrier. , 2008, International journal of pharmaceutics.

[134]  P. Opanasopit,et al.  Methylated N-(4-N,N-dimethylaminobenzyl) chitosan for novel effective gene carriers. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[135]  Yaping Li,et al.  Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: In vitro characteristics and transfection efficiency. , 2008, International journal of pharmaceutics.

[136]  M. Tabrizian,et al.  Factors influencing the transfection efficiency of ultra low molecular weight chitosan/hyaluronic acid nanoparticles. , 2009, Biomaterials.

[137]  M. Akashi,et al.  Low molecular weight chitosan-g-l-phenylalanine: Preparation, characterization, and complex formation with DNA , 2009 .

[138]  J. Kjems,et al.  Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[139]  J. Kjems,et al.  The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[140]  M. Alonso,et al.  Chitosan/cyclodextrin nanoparticles can efficiently transfect the airway epithelium in vitro. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[141]  J. Kjems,et al.  Chitosan/siRNA Nanoparticle-mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.