Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X‐ray, and MRI: Data from the osteoarthritis initiative

Osteoarthritis (OA), a multifactorial disease causing joint degeneration, often leads to severe disability. The rising rates of disability highlight the need for implementing preventative measures at early stages of the disease, which would especially benefit subjects at high risk for OA development.

[1]  M. Nevitt,et al.  Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative , 2017, European Radiology.

[2]  S. Bierma-Zeinstra,et al.  Prevention of Incident Knee Osteoarthritis by Moderate Weight Loss in Overweight and Obese Females , 2016, Arthritis care & research.

[3]  C. McCulloch,et al.  Progression of cartilage degeneration and clinical symptoms in obese and overweight individuals is dependent on the amount of weight loss: 48-month data from the Osteoarthritis Initiative. , 2016, Osteoarthritis and cartilage.

[4]  Xiaojuan Li,et al.  Fully automatic analysis of the knee articular cartilage T1ρ relaxation time using voxel‐based relaxometry , 2016, Journal of magnetic resonance imaging : JMRI.

[5]  Elena Losina,et al.  Number of Persons With Symptomatic Knee Osteoarthritis in the US: Impact of Race and Ethnicity, Age, Sex, and Obesity , 2016, Arthritis care & research.

[6]  Soo Beom Choi,et al.  Simple Scoring System and Artificial Neural Network for Knee Osteoarthritis Risk Prediction: A Cross-Sectional Study , 2016, PloS one.

[7]  L. Sharma,et al.  Clinical significance of worsening versus stable preradiographic MRI lesions in a cohort study of persons at higher risk for knee osteoarthritis , 2015, Annals of the rheumatic diseases.

[8]  S. Sheather,et al.  Best Subsets Variable Selection in Nonnormal Regression Models , 2015 .

[9]  J. Katz,et al.  Development and feasibility of a personalized, interactive risk calculator for knee osteoarthritis , 2015, BMC Musculoskeletal Disorders.

[10]  C. McCulloch,et al.  Association of Physical Activity Measured by Accelerometer, Knee Joint Abnormalities, and Cartilage T2 Measurements Obtained From 3T Magnetic Resonance Imaging: Data From the Osteoarthritis Initiative , 2015, Arthritis care & research.

[11]  C. McCulloch,et al.  A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative. , 2015, Osteoarthritis and cartilage.

[12]  C. McCulloch,et al.  Association of cartilage degeneration with four year weight gain--3T MRI data from the Osteoarthritis Initiative. , 2015, Osteoarthritis and cartilage.

[13]  C. McCulloch,et al.  Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative , 2014, Annals of the rheumatic diseases.

[14]  F. Cicuttini,et al.  Weight change and change in tibial cartilage volume and symptoms in obese adults , 2014, Annals of the Rheumatic Diseases.

[15]  M. Nevitt,et al.  A new method to measure anatomic knee alignment for large studies of OA: data from the osteoarthritis initiative. , 2014, Osteoarthritis and cartilage.

[16]  Paul Aveyard,et al.  Diet or Exercise Interventions vs Combined Behavioral Weight Management Programs: A Systematic Review and Meta-Analysis of Direct Comparisons , 2014, Journal of the Academy of Nutrition and Dietetics.

[17]  D. Hunter,et al.  The epidemiology of osteoarthritis. , 2014, Best practice & research. Clinical rheumatology.

[18]  Alina A. von Davier,et al.  Cross-Validation , 2014 .

[19]  A. Hofman,et al.  Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors , 2013, Annals of the rheumatic diseases.

[20]  C. McCulloch,et al.  Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative. , 2013, Osteoarthritis and cartilage.

[21]  Garry E Gold,et al.  Diagnosis of osteoarthritis: imaging. , 2012, Bone.

[22]  S Majumdar,et al.  Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years--data from the Osteoarthritis Initiative. , 2012, Osteoarthritis and cartilage.

[23]  M. Nevitt,et al.  Changes in knee cartilage T2 values over 24 months in subjects with and without risk factors for knee osteoarthritis and their association with focal knee lesions at baseline: Data from the osteoarthritis initiative , 2012, Journal of magnetic resonance imaging : JMRI.

[24]  L. March,et al.  Weight loss in obese people has structure-modifying effects on medial but not on lateral knee articular cartilage , 2011, Annals of the rheumatic diseases.

[25]  Katherine Kaufer Christoffel,et al.  Effect of neuromuscular warm-up on injuries in female soccer and basketball athletes in urban public high schools: cluster randomized controlled trial. , 2011, Archives of pediatrics & adolescent medicine.

[26]  C. McCulloch,et al.  Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls - data from the osteoarthritis initiative , 2011, Arthritis research & therapy.

[27]  T. Mosher,et al.  409 SIGNAL HOMOGENEITY ON CARTILAGE T2 MAPS AS A PREDICTIVE IMAGE BIOMARKER FOR RAPID SYMPTOMATIC PROGRESSION OF OA , 2011 .

[28]  S Majumdar,et al.  A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging--data from the Osteoarthritis Initiative. , 2011, Osteoarthritis and cartilage.

[29]  Michael Doherty,et al.  Nottingham knee osteoarthritis risk prediction models , 2011, Annals of the rheumatic diseases.

[30]  Ewout W Steyerberg,et al.  Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers , 2011, Statistics in medicine.

[31]  C. McCulloch,et al.  Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis initiative. , 2010, Osteoarthritis and cartilage.

[32]  David Felson,et al.  Varus and valgus alignment and incident and progressive knee osteoarthritis , 2010, Annals of the rheumatic diseases.

[33]  Olaf Dietrich,et al.  T2 measurement in articular cartilage: Impact of the fitting method on accuracy and precision at low SNR , 2009, Magnetic resonance in medicine.

[34]  Stuart Crozier,et al.  Automatic Segmentation and Quantitative Analysis of the Articular Cartilages From Magnetic Resonance Images of the Knee , 2010, IEEE Transactions on Medical Imaging.

[35]  David Felson,et al.  Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies , 2009, BMJ : British Medical Journal.

[36]  J. Niinimäki,et al.  Prevalence of Degenerative Imaging Findings in Lumbar Magnetic Resonance Imaging Among Young Adults , 2009, Spine.

[37]  F. Eckstein,et al.  One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status , 2008, Annals of the rheumatic diseases.

[38]  Erika Schneider,et al.  The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee. , 2008, Osteoarthritis and cartilage.

[39]  E. Roos,et al.  Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritis. , 2005, Arthritis and rheumatism.

[40]  H. Genant,et al.  Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. , 2004, Osteoarthritis and cartilage.

[41]  David R. Anderson,et al.  Model selection and multimodel inference : a practical information-theoretic approach , 2003 .

[42]  L. Sharma,et al.  The role of knee alignment in disease progression and functional decline in knee osteoarthritis. , 2001, JAMA.

[43]  Y. Xia,et al.  Magic-Angle Effect in Magnetic Resonance Imaging of Articular Cartilage: A Review , 2000, Investigative radiology.

[44]  R. Wilson,et al.  Regressions by Leaps and Bounds , 2000, Technometrics.

[45]  S. Lyman,et al.  The effect of neuromuscular training on the incidence of knee injury in female athletes: a prospective study. , 2000, The American journal of sports medicine.

[46]  N. Bellamy,et al.  Minimal perceptible clinical improvement with the Western Ontario and McMaster Universities osteoarthritis index questionnaire and global assessments in patients with osteoarthritis. , 2000, The Journal of rheumatology.

[47]  Aaron J. Miller,et al.  The use of power images to perform quantitative analysis on low SNR MR images. , 1993, Magnetic resonance imaging.

[48]  R. Villar.  Knee replacement. , 1990, The Practitioner.

[49]  E. DeLong,et al.  Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. , 1988, Biometrics.

[50]  R. Bryan,et al.  Total knee replacement. , 1981, Instructional course lectures.

[51]  J. Kellgren,et al.  Radiological Assessment of Osteo-Arthrosis , 1957, Annals of the rheumatic diseases.