Quantification of ex-vivo tissue activity by polarization dynamics imaging using Jones matrix optical coherence tomography

A new method for quantitative assessment of tissue dynamics and activity is presented. The method is based on polarizationsensitive optical coherence tomography. Temporal variance of birefringence and temporal polarization uniformity are used to assess the tissue dynamics. These methods are applied to hourly time-course evaluation of tissue activity of ex-vivo dissected mouse heart.