Synthetic approaches to long-wavelength photosensitizers for photodynamic therapy

Syntheses and chemical characterization of a number of new porphyrin-derived sensitizers related to ''benzoporphyrin derivative'' (BPD) are described. The work discussed centers in solving the isomer problem inherent in BPD synthesis from protoporphyrin IX, with regard to the 2- and 4-vinyls and the 6- and 7-propionic acid groups (Fischer nomenclature).

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