Fuzzy Expert System for Type 2 Diabetes Mellitus (T2DM) Management Using Dual Inference Mechanism

Fuzzy logic is an important technique for modeling uncertainty in expert systems (i.e., in cases where inferencing of conclusion from given evidence is difficult to ascertain). This paper proposes a fuzzy expert system framework that combines case-based and rule-based reasoning effectively to produce a usable tool for Type 2 Diabetes Mellitus (T2DM) management. The major targets are on combined therapies (i.e., lifestyle and pharmacologic), and the recognition of management data dynamics (trends) during reasoning. The Knowledge base (KB) is constructed using fuzzified input values which are subsequently de-fuzziffied after reasoning, to produce crisp outputs to patients in the form of low-risk advice. The extended framework features a combined reasoning approach for simplified output in the form of decision support for clinicians. With seven operational input variables and two additional pre-set variables for testing, the results of the proposed work will be compared with other methods using similarity to expert’s decision as metrics.

[1]  J. Lis,et al.  Automatic meal planning using artificial intelligence algorithms in computer aided diabetes therapy , 2000, 2009 4th International Conference on Autonomous Robots and Agents.

[2]  Isabelle Bichindaritz,et al.  Case-Based Reasoning in the Health Sciences: Why It Matters for the Health Sciences and for CBR , 2008, ECCBR.

[3]  Matthew Crosby,et al.  Association for the Advancement of Artificial Intelligence , 2014 .

[4]  Abdul V. Roudsari,et al.  Integrating model-based decision support in a multi-modal reasoning system for managing type 1 diabetic patients , 2003, Artif. Intell. Medicine.

[5]  Farath Arshad,et al.  Diabetes Online - Patient Management (DO-PM) , 2009, 2009 Second International Conference on Developments in eSystems Engineering.

[6]  Isabelle Bichindaritz,et al.  Case-based reasoning in the health sciences: What's next? , 2006, Artif. Intell. Medicine.

[7]  Cynthia R. Marling,et al.  Emerging Applications for Intelligent Diabetes Management , 2011, AI Mag..

[8]  I. Turksen,et al.  Measurement of Membership Functions: Theoretical and Empirical Work , 2000 .

[9]  Charles E. Thorpe,et al.  Intelligent Diabetes Assistant: Using machine learning to help manage diabetes , 2008, 2008 IEEE/ACS International Conference on Computer Systems and Applications.

[10]  E D Lehmann,et al.  AIDA: an automated insulin dosage advisor. , 1992, Proceedings. Symposium on Computer Applications in Medical Care.

[11]  Stephen W. Sorensen,et al.  The Cost-Effectiveness of Lifestyle Modification or Metformin in Preventing Type 2 Diabetes in Adults with Impaired Glucose Tolerance , 2005, Annals of Internal Medicine.

[12]  O. Ober Diabetes Prevention Program , 2012 .

[13]  Ping Zhang,et al.  The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention , 2012, Diabetes Care.

[14]  C. von Altrock,et al.  Recent successful fuzzy logic applications in industrial automation , 1996, Proceedings of IEEE 5th International Fuzzy Systems.

[15]  M. E. Cintra,et al.  A comparative study on classic machine learning and fuzzy approaches for classification problems , 2009 .

[16]  Joanna Koleszynska GIGISim - The Intelligent Telehealth System: Computer Aided Diabetes Management - A New Review , 2007, KES.

[17]  Nicola J Cooper,et al.  Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis , 2007, BMJ : British Medical Journal.