[Dimensional ridge alterations following tooth extraction. An experimental study in the dog].

The aim of the present study was to histologically evaluate extraction wound healing after socket preservation using a beta-TCP root taper.Ten dogs were used in the study. Immediately following careful extraction of the first premolar of the lower jaw the extraction sockets were filled using a chair-side thermically formed polylactide-linked root taper (RT). To avoid contamination, a further polylactide barrier covered the crestal surface of the taper. Untreated extraction sites of the opposite side served as control. After three and six months of healing, the animals were sacrified and dissected blocks were prepared for histomorphometrical analysis. Following parameters were evaluated: difference between lingual and buccal bone height, lingual and buccal alveolar wall and total bone width 1, 3 and 5mm underneath the top of the respective crest. During the entire study period healing was uneventful for all animals. Histological analysis of three months specimens revealed a definable area of minor mineralized bone within the former extraction sockets in both RT and control group. In the test group small areas of material organized by connective tissue but no remnants of the bone substitute material could be observed. After six months the borderline between new and pre-existing bone had disappeared. Histomorphometric analysis revealed no statistically significant differences between test and control group after three or six months (p>0.05, paired T-test). Within the limits of the present study it was concluded that the application of polylactide-stabilized RT does not improve the dimensional ridge alterations after tooth extraction.

[1]  D. Waite,et al.  Alveolar ridge maintenance with hydroxylapatite ceramic cones in humans. , 1986, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[2]  J. Lindhe,et al.  Dimensional ridge alterations following tooth extraction. An experimental study in the dog. , 2005, Journal of clinical periodontology.

[3]  H. Tal,et al.  Efficacy of porous bovine bone mineral in various types of osseous deficiencies: clinical observations and literature review. , 2001, The International journal of periodontics & restorative dentistry.

[4]  H. Greenwell,et al.  Ridge preservation with freeze-dried bone allograft and a collagen membrane compared to extraction alone for implant site development: a clinical and histologic study in humans. , 2003, Journal of periodontology.

[5]  H. Luder,et al.  Biocompatibility of b-Tricalcium Phosphate Root Replicas in Porcine Tooth Extraction Sockets - A Correlative Histological, Ultrastructural, and X-ray Microanalytical Pilot Study , 2006, Journal of biomaterials applications.

[6]  A. N. Cranin,et al.  Hydroxylapatite (H/A) particulate versus cones as post-extraction implants in humans. Parts I & II. , 1988, Journal of biomedical materials research.

[7]  T. Berglundh,et al.  Healing of human extraction sockets filled with Bio-Oss. , 2003, Clinical oral implants research.

[8]  J. Kent,et al.  Alveolar ridge maintenance with solid nonporous hydroxylapatite root implants. , 1984, Oral surgery, oral medicine, and oral pathology.

[9]  P. Klokkevold,et al.  Influence of bioactive glass on changes in alveolar process dimensions after exodontia. , 2000, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[10]  P. N. R. Nair Pn,et al.  Observations on healing of human tooth extraction sockets implanted with bioabsorbable polylactic-polyglycolic acids (PLGA) copolymer root replicas: a clinical, radiographic, and histologic follow-up report of 8 cases. , 2004, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[11]  B. J. Meyer,et al.  Polylactic acid (PLA) root replica in ridge maintenance after loss of a vertically fractured incisor. , 1996, Endodontics & dental traumatology.

[12]  M. Massler,et al.  Alveolar ridge resorption following tooth extraction. , 1967, The Journal of prosthetic dentistry.

[13]  J. Ouhayoun,et al.  Bone regeneration in extraction sites after immediate placement of an e-PTFE membrane with or without a biomaterial. A report on 12 consecutive cases. , 1996, Clinical oral implants research.

[14]  A. Vernino,et al.  Ridge preservation of dentition with severe periodontitis. , 2000, Compendium of continuing education in dentistry.

[15]  D. Atwood Some clinical factors related to rate of resorption of residual ridges , 1962 .

[16]  H. Moroi,et al.  GBR in human extraction sockets and ridge defects prior to implant placement: clinical results and histologic evidence of osteoblastic and osteoclastic activities in DFDBA. , 1999, The International journal of periodontics & restorative dentistry.

[17]  J. Wennström,et al.  Dental Abstracts , 2005, Journal of clinical periodontology.

[18]  L. Landi,et al.  Histomorphometric evaluation of extraction sockets and deficient alveolar ridges treated with allograft and barrier membrane: a pilot study. , 1999, The International journal of oral & maxillofacial implants.

[19]  P. Klokkevold,et al.  A bone regenerative approach to alveolar ridge maintenance following tooth extraction. Report of 10 cases. , 1997, Journal of periodontology.

[20]  L. G. Breault,et al.  Ridge preservation utilizing an acellular dermal allograft and demineralized freeze-dried bone allograft: Part II. Immediate endosseous implant placement. , 2000, Journal of periodontology.

[21]  A. Wenzel,et al.  Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. , 2003, The International journal of periodontics & restorative dentistry.

[22]  A. Kiliç,et al.  Alveolar ridge reconstruction and/or preservation using root form bioglass cones. , 1998, Journal of clinical periodontology.

[23]  Klokkevold Pr,et al.  Aesthetic management of extractions for implant site development: delayed versus staged implant placement. , 1999 .

[24]  K. de Groot,et al.  Immediate dental root implants from synthetic dense calcium hydroxylapatite. , 1979, The Journal of prosthetic dentistry.

[25]  A Tallgren,et al.  The continuing reduction of the residual alveolar ridges in complete denture wearers: a mixed-longitudinal study covering 25 years. , 2003, The Journal of prosthetic dentistry.

[26]  P. Klokkevold,et al.  Preservation of alveolar bone in extraction sockets using bioabsorbable membranes. , 1998, Journal of periodontology.

[27]  M. Wiesen,et al.  Preservation of the alveolar ridge at implant sites. , 1998, Periodontal clinical investigations : official publication of the Northeastern Society of Periodontists.