General safety guidances in stem cell bank installations.

The use of cell cultures in research and in regenerative medicine programs has increased in the past few years, and control of the risks inherent to these procedures should be increased. People who work in stem cell bank installations should be aware of the risks implied in their work and take necessary self-protection measures for the known and unidentified risks. Work in stem cell bank installations is subject to different types of risks, such as toxicologic, carcinogen and, mainly, infectious risks. Different types of safety measurements should be distinguished and secured, for example for protection of personnel, protection of the cell cultures and protection in general of humans and the environment.

[1]  S. Kusne,et al.  Transmission of rabies virus from an organ donor to four transplant recipients , 2005, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[2]  W. Heneine,et al.  Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[3]  K. Zakrzewska,et al.  Presence of TT virus DNA in bone marrow cells from hematologic patients. , 2004, The new microbiologica.

[4]  Jonathan Y. Richmond,et al.  Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets , 2000 .

[5]  Kennedy Da,et al.  Microbiological safety cabinets: selection, installation, testing and use. , 2000 .

[6]  Jonathan Y. Richmond,et al.  Biosafety in microbiological and biomedical laboratories , 1999 .

[7]  G. Siegl,et al.  Evidence for persistence of human parvovirus B19 DNA in bone marrow , 1997, Journal of medical virology.

[8]  H. Takeuchi,et al.  Detection of latent infection by Epstein-Barr virus in peripheral blood cells of healthy individuals and in non-neoplastic tonsillar tissue from patients by reverse transcription-polymerase chain reaction. , 1996, Journal of virological methods.

[9]  A. Goldstone,et al.  Hepatitis B transmission from contaminated cryopreservation tank , 1995, The Lancet.

[10]  D L Sewell,et al.  Laboratory-associated infections and biosafety , 1995, Clinical microbiology reviews.

[11]  J. Richardson,et al.  Laboratory safety : principles and practices , 1995 .

[12]  M. Nettleman,et al.  Tuberculosis Control Strategies: The Cost of Particulate Respirators , 1994, Annals of Internal Medicine.

[13]  F. Campagnari,et al.  The contained use of genetically modified microorganisms, GMMs (Directive 90/219/EEC). , 1994 .

[14]  W Nicklas,et al.  Contamination of transplantable tumors, cell lines, and monoclonal antibodies with rodent viruses. , 1993, Laboratory animal science.

[15]  R. Gershon,et al.  Safety in the clinical microbiology laboratory , 1993 .

[16]  R. Pearson,et al.  Reducing blood and body fluid exposures among clinical laboratory workers. Meeting the OSHA standards. , 1992, Clinical laboratory management review : official publication of the Clinical Laboratory Management Association.

[17]  J. Richardson,et al.  Biological safety cabinetry , 1991, Clinical Microbiology Reviews.

[18]  S. Ostroff,et al.  Virus zoonoses and their potential for contamination of cell cultures. , 1991, Developments in biological standardization.

[19]  S. Bolin,et al.  Viral contamination of fetal bovine serum used for tissue culture: risks and concerns. , 1991, Developments in biological standardization.

[20]  J. A. Morello.  Laboratory-Acquired Infections: History, Incidence, Causes and Prevention , 1988 .

[21]  J. Luka.  Activation of Epstein-Barr virus in latently infected cell lines. , 1988, Journal of virological methods.

[22]  B. Howard.  Clinical and Pathogenic Microbiology , 1987 .

[23]  C. Collins.  Laboratory-acquired Infections: History, Incidence, Causes and Prevention , 1983 .

[24]  E. Bruck,et al.  National Committee for Clinical Laboratory Standards. , 1980, Pediatrics.

[25]  S. Malcolm,et al.  Guidelines for Research Involving Recombinant DNA Molecules , 1978, Federal register.

[26]  Ellen Jo Baron,et al.  Manual of clinical microbiology , 1975 .