A deficit in strabismic amblyopia for global shape detection

Using a task which relied upon the detection of sinusoidal deformations from circularity, we show that strabismic amblyopes exhibit deficits which are not critically dependent on either the scale of deformation or the spatial frequency characteristics of the stimulus (circular D4) itself. We show that this loss is not due to the restricted passband of the amblyopic eye. Furthermore, in a pedestal distortion experiment, we show that the suprathreshold form of this loss is consistent with an elevated level of 'intrinsic noise' rather than a loss in 'sampling efficiency'.

[1]  D. V. van Essen,et al.  Selectivity for polar, hyperbolic, and Cartesian gratings in macaque visual cortex. , 1993, Science.

[2]  W. Weibull.  A Statistical Distribution Function of Wide Applicability , 1951 .

[3]  R. Watt,et al.  Shape recognition in amblyopia , 1987, Vision Research.

[4]  R. Sireteanu,et al.  Monocular geometry is selectively distorted in the central visual field of strabismic amblyopes. , 1989, Investigative ophthalmology & visual science.

[5]  H E Bedell,et al.  Spatial aberrations and acuity in strabismus and amblyopia. , 1985, Investigative Ophthalmology and Visual Science.

[6]  Steven C. Dakin,et al.  Are judgements of circularity local or global? , 1999, Vision Research.

[7]  D M Levi,et al.  Spatio-temporal interactions in anisometropic and strabismic amblyopia. , 1977, Investigative ophthalmology & visual science.

[8]  D. Pollen,et al.  Spatial and temporal frequency selectivity of neurones in visual cortical areas V1 and V2 of the macaque monkey. , 1985, The Journal of physiology.

[9]  R. F. Hess,et al.  The threshold contrast sensitivity function in strabismic amblyopia: Evidence for a two type classification , 1977, Vision Research.

[10]  Yi-Zhong Wang.  Filtering, Sampling and Aliasing in Peripheral Vision. , 1996 .

[11]  D. C. Essen,et al.  Neural responses to polar, hyperbolic, and Cartesian gratings in area V4 of the macaque monkey. , 1996, Journal of neurophysiology.

[12]  Y. Chino,et al.  Effects of rearing kittens with convergent strabismus on development of receptive-field properties in striate cortex neurons. , 1983, Journal of neurophysiology.

[13]  Ruxandra Sireteanu,et al.  Two-dimensional spatial distortions in human strabismic amblyopia , 1991, Vision Research.

[14]  Dennis M. Levi,et al.  Hyperacuity and amblyopia , 1982, Nature.

[15]  Ian E. Holliday,et al.  The spatial localization deficit in amblyopia , 1992, Vision Research.

[16]  S. Klein,et al.  Spatial uncertainty and sampling efficiency in amblyopic position acuity , 1998, Vision Research.

[17]  Hugh R. Wilson,et al.  Model of peripheral and amblyopic hyperacuity , 1991, Vision Research.

[18]  S. Klein,et al.  Sampling in spatial vision , 1986, Nature.

[19]  M. C. Flom,et al.  Monocular spatial distortion in strabismic amblyopia. , 1981, Investigative ophthalmology & visual science.

[20]  Dennis M. Levi,et al.  Spatial localization in normal and amblyopic vision , 1983, Vision Research.

[21]  David J. Field,et al.  Contour integration in strabismic amblyopia: The sufficiency of an explanation based on positional uncertainty , 1997, Vision Research.

[22]  O. Sundin,et al.  The Pax-6 homeobox gene is expressed throughout the corneal and conjunctival epithelia. , 1997, Investigative ophthalmology & visual science.

[23]  R. Hess.  Developmental sensory impairment: amblyopia or tarachopia? , 1982, Human neurobiology.

[24]  Jacob Nachmias,et al.  On the psychometric function for contrast detection , 1981, Vision Research.

[25]  R. Hess,et al.  Positional Loss in Strabismic Amblyopia: Inter-relationship of Alignment Threshold, Bias, Spatial Scale and Eccentricity , 1996, Vision Research.

[26]  D G Pelli,et al.  The VideoToolbox software for visual psychophysics: transforming numbers into movies. , 1997, Spatial vision.

[27]  Vision Research , 1961, Nature.

[28]  H. Wilson,et al.  Concentric orientation summation in human form vision , 1997, Vision Research.

[29]  D H Brainard,et al.  The Psychophysics Toolbox. , 1997, Spatial vision.