The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.
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Dan Chen | Yang Wang | Quentin Liu | Zefeng Wang | Zefeng Wang | Quentin Liu | Dan Chen | S. Shao | Yihsuan S. Tsai | Shujuan Shao | Daniel Dominguez | Yihsuan S Tsai | Yang Wang | Haili Qian | H. Qian | Daniel Dominguez
[1] N. Danial,et al. BCL-2 Family Proteins: Critical Checkpoints of Apoptotic Cell Death , 2007, Clinical Cancer Research.
[2] J. Manley,et al. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. , 2010, Genes & development.
[3] Jung-Chun Lin,et al. Exon Selection in α-Tropomyosin mRNA Is Regulated by the Antagonistic Action of RBM4 and PTB , 2005, Molecular and Cellular Biology.
[4] C. Burge,et al. Splicing regulation: from a parts list of regulatory elements to an integrated splicing code. , 2008, RNA.
[5] A. Pause,et al. An oxygen-regulated switch in the protein synthesis machinery , 2012, Nature.
[6] K. Schulze-Osthoff,et al. Regulation of apoptosis by alternative pre-mRNA splicing. , 2005, Molecular cell.
[7] A. Krainer,et al. S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1. , 2013, Cell reports.
[8] R. Kole,et al. Anti-tumor activity of splice-switching oligonucleotides , 2010, Nucleic acids research.
[9] A. Krainer,et al. THE SPLICING FACTOR SRSF1 REGULATES APOPTOSIS AND PROLIFERATION TO PROMOTE MAMMARY EPITHELIAL CELL TRANSFORMATION , 2011, Nature Structural &Molecular Biology.
[10] M. Olive,et al. hnRNP A1 Recruited to an Exon In Vivo Can Function as an Exon Splicing Silencer , 1999, Molecular and Cellular Biology.
[11] Zefeng Wang,et al. The splicing activator DAZAP1 integrates splicing control into MEK/Erk regulated cell proliferation and migration , 2014, Nature Communications.
[12] C. Burge,et al. A Complex Network of Factors with Overlapping Affinities Repress Splicing through Intronic Elements , 2012, Nature Structural &Molecular Biology.
[13] Chonghui Cheng,et al. CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. , 2011, The Journal of clinical investigation.
[14] Sherif Abou Elela,et al. Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing. , 2013, Cancer treatment and research.
[15] S. Lam,et al. Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression , 2012, Genome research.
[16] Jung-Chun Lin,et al. RNA-binding Motif Protein 4 Translocates to Cytoplasmic Granules and Suppresses Translation via Argonaute2 during Muscle Cell Differentiation* , 2009, The Journal of Biological Chemistry.
[17] Premkumar Vummidi Giridhar,et al. CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches , 2013, Experimental biology and medicine.
[18] J. Venables. Unbalanced alternative splicing and its significance in cancer , 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.
[19] Jung-Chun Lin,et al. RBM4 Promotes Pancreas Cell Differentiation and Insulin Expression , 2012, Molecular and Cellular Biology.
[20] Z. Szallasi,et al. Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients. , 2012, Endocrine-related cancer.
[21] Yi Xing,et al. An ESRP‐regulated splicing programme is abrogated during the epithelial–mesenchymal transition , 2010, The EMBO journal.
[22] F. Pépin,et al. Stromal gene expression predicts clinical outcome in breast cancer , 2008, Nature Medicine.
[23] R. Amann,et al. Predictive Identification of Exonic Splicing Enhancers in Human Genes , 2022 .
[24] C. Bortner,et al. Modification of Alternative Splicing of Bcl-x Pre-mRNA in Prostate and Breast Cancer Cells , 2001, The Journal of Biological Chemistry.
[25] Wen Chang,et al. A novel splicing regulator shares a nuclear import pathway with SR proteins , 2003, The EMBO journal.
[26] Leandro Quadrana,et al. Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT , 2005, Nature Structural &Molecular Biology.
[27] Hiroshi Tanaka,et al. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell , 2012, Nature Communications.
[28] J. Valcárcel,et al. RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation. , 2013, Molecular cell.
[29] D. Bates,et al. Hallmarks of alternative splicing in cancer , 2014, Oncogene.
[30] T. Maniatis,et al. Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing. , 1998, Molecular cell.
[31] A. Krainer,et al. The gene encoding the splicing factor SF2/ASF is a proto-oncogene , 2007, Nature Structural &Molecular Biology.
[32] Jung-Chun Lin,et al. Exon selection in alpha-tropomyosin mRNA is regulated by the antagonistic action of RBM4 and PTB. , 2005, Molecular and cellular biology.
[33] Wei Guo,et al. Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells , 2005, Molecular Cancer Therapeutics.
[34] Sherif Abou Elela,et al. Anticancer drugs affect the alternative splicing of Bcl-x and other human apoptotic genes , 2008, Molecular Cancer Therapeutics.
[35] Jane Y. Wu,et al. RBM4 Interacts with an Intronic Element and Stimulates Tau Exon 10 Inclusion* , 2006, Journal of Biological Chemistry.
[36] A. Busch,et al. Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms. , 2013, RNA.
[37] A. Krainer,et al. The splicing-factor oncoprotein SF2/ASF activates mTORC1 , 2008, Proceedings of the National Academy of Sciences.
[38] Sherif Abou Elela,et al. Identification of alternative splicing markers for breast cancer. , 2008, Cancer research.
[39] S. Dehm. mRNA splicing variants: exploiting modularity to outwit cancer therapy. , 2013, Cancer research.
[40] Zefeng Wang,et al. Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules , 2012, Nature Structural &Molecular Biology.
[41] C. Ghigna,et al. Alternative Splicing and Tumor Progression , 2008, Current genomics.
[42] Anna M. Heidenblut,et al. Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions , 2005, Oncogene.
[43] F. Clark,et al. Understanding alternative splicing: towards a cellular code , 2005, Nature Reviews Molecular Cell Biology.
[44] Zefeng Wang,et al. A day in the life of the spliceosome , 2014, Nature Reviews Molecular Cell Biology.
[45] Yang Wang,et al. Engineering splicing factors with designed specificities , 2009, Nature Methods.
[46] S. Cory,et al. The Bcl-2 apoptotic switch in cancer development and therapy , 2007, Oncogene.
[47] Robert Wechsler-Reya,et al. BIN1 is a novel MYC–interacting protein with features of a tumour suppressor , 1996, Nature Genetics.
[48] Jung-Chun Lin,et al. Cell stress modulates the function of splicing regulatory protein RBM4 in translation control , 2007, Proceedings of the National Academy of Sciences.
[49] Brian J. Smith,et al. Structure-guided design of a selective BCL-X(L) inhibitor. , 2013, Nature chemical biology.
[50] Sherif Abou Elela,et al. Reprogramming Alternative Pre-messenger RNA Splicing through the Use of Protein-binding Antisense Oligonucleotides* , 2003, Journal of Biological Chemistry.