Expression Profiling-Based Subtyping Identifies Novel Non-small Cell Lung Cancer Subgroups and Implicates Putative Resistance to Pemetrexed Therapy
暂无分享,去创建一个
H. Hoogsteden | F. Grosveld | J. Aerts | J. Hou | B. den Hamer | M. D. den Bakker | S. Philipsen | J. Hegmans | M. Lambers | Margaretha E. H. Lambers | Bianca den Hamer
[1] J. Ahn,et al. Significance of Thymidylate Synthase and Thyroid Transcription Factor 1 Expression in Patients with Nonsquamous Non-small Cell Lung Cancer Treated with Pemetrexed-Based Chemotherapy , 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[2] Yukiko Nakamura,et al. Efficacy of gefitinib for non‐adenocarcinoma non‐small‐cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of published reports , 2011, Cancer science.
[3] G. Scagliotti,et al. Treatment-by-Histology Interaction Analyses in Three Phase III Trials Show Superiority of Pemetrexed in Nonsquamous Non-small Cell Lung Cancer , 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[4] W. V. van IJcken,et al. Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction , 2010, PloS one.
[5] S. Koscielny. Why Most Gene Expression Signatures of Tumors Have Not Been Useful in the Clinic , 2010, Science Translational Medicine.
[6] G. Scagliotti,et al. Differential Thymidylate Synthase Expression in Different Variants of Large-Cell Carcinoma of the Lung , 2009, Clinical Cancer Research.
[7] K. Krejcy,et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study , 2009, The Lancet.
[8] G. Otterson,et al. Pulmonary neuroendocrine/carcinoid tumors , 2009, Cancer.
[9] Gregory J Riely,et al. Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an Online Tumor Registry of Clinical Trials , 2009, Clinical Cancer Research.
[10] S. Kaasa,et al. Phase III study by the Norwegian lung cancer study group: pemetrexed plus carboplatin compared with gemcitabine plus carboplatin as first-line chemotherapy in advanced non-small-cell lung cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] E. Esteban,et al. Pemetrexed in first-line treatment of non-small cell lung cancer. , 2009, Cancer treatment reviews.
[12] L. R. Moreira,et al. Correlation Between Thymidylate Synthase Protein Expression and Gene Polymorphism with Clinicopathological Parameters in Colorectal Carcinoma , 2009, International journal of surgical pathology.
[13] A. Nobel,et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] G. Scagliotti,et al. The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. , 2009, The oncologist.
[15] C. Obasaju,et al. Clinical Efficacy and Predictive Molecular Markers of Neoadjuvant Gemcitabine and Pemetrexed in Resectable Non-small Cell Lung Cancer , 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[16] Johan Vansteenkiste,et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[17] Irvin M Modlin,et al. Bronchopulmonary neuroendocrine tumors , 2008, Cancer.
[18] G. Scagliotti,et al. Thymidylate Synthase Expression in Gastroenteropancreatic and Pulmonary Neuroendocrine Tumors , 2008, Clinical Cancer Research.
[19] G. Scagliotti,et al. Neuro-endocrine tumours of the lung. A review of relevant pathological and molecular data , 2007, Virchows Archiv.
[20] R. Perez-soler,et al. Schedule-Dependent Cytotoxic Synergism of Pemetrexed and Erlotinib in Human Non–Small Cell Lung Cancer Cells , 2007, Clinical Cancer Research.
[21] H. Pospisil,et al. In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression , 2007, Investigational New Drugs.
[22] Lisa A Carey,et al. Gene-expression analysis and the basal-like breast cancer subtype. , 2007, Future oncology.
[23] J. Bertino,et al. Role of Pemetrexed in Non-Small Cell Lung Cancer , 2007, Cancer investigation.
[24] G. Scagliotti,et al. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase , 2006, Cancer.
[25] A. Nobel,et al. Concordance among Gene-Expression – Based Predictors for Breast Cancer , 2011 .
[26] Yi Zhang,et al. Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung. , 2006, Cancer research.
[27] Takayuki Kosaka,et al. Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] Jeffrey T. Chang,et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies , 2006, Nature.
[29] Carl Virtanen,et al. Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization , 2005, Oncogene.
[30] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[31] Elisa Giovannetti,et al. Cellular and Pharmacogenetics Foundation of Synergistic Interaction of Pemetrexed and Gemcitabine in Human Non–Small-Cell Lung Cancer Cells , 2005, Molecular Pharmacology.
[32] E. Felip,et al. The biology of non-small-cell lung cancer: identifying new targets for rational therapy. , 2004, Lung cancer.
[33] Charles A Powell,et al. Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. , 2003, The American journal of pathology.
[34] M. Tyers,et al. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. , 2002, Cancer research.
[35] R. Tibshirani,et al. Diagnosis of multiple cancer types by shrunken centroids of gene expression , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[36] D. Botstein,et al. Diversity of gene expression in adenocarcinoma of the lung , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[37] P. Paoletti,et al. Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors. , 2001, The oncologist.
[38] T. Grogan,et al. Discrepancies in clinical laboratory testing of eligibility for trastuzumab therapy: apparent immunohistochemical false-positives do not get the message. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] R. Tibshirani,et al. Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[40] Christian A. Rees,et al. Molecular portraits of human breast tumours , 2000, Nature.
[41] Joel H. Saltz,et al. Classification of small cell lung cancer and pulmonary carcinoid by gene expression profiles. , 1999, Cancer research.
[42] J. Mesirov,et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. , 1999, Science.
[43] W. Travis,et al. Reproducibility of neuroendocrine lung tumor classification. , 1998, Human pathology.
[44] E. Lander,et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. , 2001, Proceedings of the National Academy of Sciences of the United States of America.