Network pharmacology and experimental verification to explore the anti-migraine mechanism of Yufeng Ningxin Tablet.

[1]  Pinyi Liu,et al.  Bergapten attenuates microglia-mediated neuroinflammation and ischemic brain injury by targeting Kv1.3 and Carbonyl reductase 1. , 2022, European journal of pharmacology.

[2]  M. Togha,et al.  Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2 , 2022, The Journal of Headache and Pain.

[3]  H. Hoe,et al.  Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling , 2021, International journal of molecular sciences.

[4]  B. Chen,et al.  Effects of ligustrazine on the expression of neurotransmitters in the trigeminal ganglion of a rat migraine model , 2021, Annals of translational medicine.

[5]  Yong Tang,et al.  Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation , 2021, The Journal of Headache and Pain.

[6]  R. Burch,et al.  The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice , 2021, Headache.

[7]  Shushen Lin,et al.  Cirsilineol attenuates LPS‐induced inflammation in both in vivo and in vitro models via inhibiting TLR‐4/NFkB/IKK signaling pathway , 2021, Journal of biochemical and molecular toxicology.

[8]  Shao Li,et al.  TCM network pharmacology: A new trend towards combining computational, experimental and clinical approaches. , 2021, Chinese journal of natural medicines.

[9]  Ting-ting Feng,et al.  An integrated network pharmacology and RNA-Seq approach for exploring the preventive effect of Lonicerae japonicae flos on LPS-induced acute lung injury , 2020, Journal of Ethnopharmacology.

[10]  K. Soliman,et al.  Involvement of NFƙB and MAPK signaling pathways in the preventive effects of Ganoderma lucidum on the inflammation of BV-2 microglial cells induced by LPS , 2020, Journal of Neuroimmunology.

[11]  Yun Dai,et al.  NO up-regulates migraine-related CGRP via activation of an Akt/GSK-3β/NF-κB signaling cascade in trigeminal ganglion neurons , 2020, Aging.

[12]  A. Maassenvandenbrink,et al.  Pharmacological treatment of migraine: CGRP and 5-HT beyond the triptans. , 2020, Pharmacology & therapeutics.

[13]  Jianliang Fu,et al.  Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells. , 2019, Molecular immunology.

[14]  Wen Wen,et al.  Fructus Viticis methanolic extract attenuates trigeminal hyperalgesia in migraine by regulating injury signal transmission , 2019, Experimental and therapeutic medicine.

[15]  Xingyu Chen,et al.  Rhynchophylline attenuates migraine in trigeminal nucleus caudalis in nitroglycerin-induced rat model by inhibiting MAPK/NF-кB signaling , 2019, Molecular and Cellular Biochemistry.

[16]  E. Rota,et al.  Novelty in Inflammation and Immunomodulation in Migraine. , 2019, Current pharmaceutical design.

[17]  D. Borsook,et al.  Nitroglycerin as a comparative experimental model of migraine pain: From animal to human and back , 2019, Progress in Neurobiology.

[18]  Kirk W. Johnson,et al.  CGRP and the Trigeminal System in Migraine , 2019, Headache.

[19]  E. Loder,et al.  Calcitonin Gene-Related Peptide Monoclonal Antibody Treatments for Migraine , 2019, JAMA internal medicine.

[20]  P. Gressens,et al.  Lipopolysaccharide‐induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo , 2019, Glia.

[21]  Yie Hou Lee,et al.  Challenges and emergent solutions for LC-MS/MS based untargeted metabolomics in diseases. , 2018, Mass spectrometry reviews.

[22]  Liyong Wang,et al.  Efficacy of Nimodipine Plus Yufeng Ningxin Tablets for Patients with Frequent Migraine , 2018, Pharmacology.

[23]  A. Pradhan,et al.  Targeted Nitric Oxide Synthase Inhibitors for Migraine , 2018, Neurotherapeutics.

[24]  G. Knudsen,et al.  High brain serotonin levels in migraine between attacks: A 5-HT4 receptor binding PET study , 2018, NeuroImage: Clinical.

[25]  Jia-yu Zhang,et al.  Rapid Screening and Identification of Daidzein Metabolites in Rats Based on UHPLC-LTQ-Orbitrap Mass Spectrometry Coupled with Data-Mining Technologies , 2018, Molecules.

[26]  Zhiguo Yu,et al.  Simultaneous determination and pharmacokinetics of fourteen bioactive compounds in rat plasma by LC-ESI-MS/MS following intravenous injection of Gegen-Sanqi compatibility solution. , 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[27]  Simon Mitchell,et al.  Signaling via the NFκB system , 2016, Wiley interdisciplinary reviews. Systems biology and medicine.

[28]  E. Choi,et al.  Compromised MAPK signaling in human diseases: an update , 2015, Archives of Toxicology.

[29]  Panpan Guo,et al.  Simultaneous determination of linarin, naringenin and formononetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study after oral administration of Bushen Guchi Pill. , 2015, Biomedical chromatography : BMC.

[30]  A. Capuano,et al.  Correlation between algogenic effects of calcitonin-gene-related peptide (CGRP) and activation of trigeminal vascular system, in an in vivo experimental model of nitroglycerin-induced sensitization. , 2014, European journal of pharmacology.

[31]  K. Nho,et al.  An ethyl acetate fraction derived from Houttuynia cordata extract inhibits the production of inflammatory markers by suppressing NF-кB and MAPK activation in lipopolysaccharide-stimulated RAW 264.7 macrophages , 2014, BMC Complementary and Alternative Medicine.

[32]  P. Martínez-Camblor,et al.  Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine , 2013, Neurology.

[33]  K. Lee,et al.  A metabolite of daidzein, 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K. , 2013, Molecular nutrition & food research.

[34]  M. Ferrari,et al.  Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant mice , 2013, PAIN®.

[35]  Á. Párdutz,et al.  Evaluation of c-Fos immunoreactivity in the rat brainstem nuclei relevant in migraine pathogenesis after electrical stimulation of the trigeminal ganglion , 2013, Neurological Sciences.

[36]  P. Magni,et al.  Parthenolide Inhibits the LPS‐induced Secretion of IL‐6 and TNF‐α and NF‐κB Nuclear Translocation in BV‐2 Microglia , 2012, Phytotherapy research : PTR.

[37]  A. Srikiatkhachorn,et al.  Serotonin Depletion Leads to Cortical Hyperexcitability and Trigeminal Nociceptive Facilitation via the Nitric Oxide Pathway , 2011, Headache.

[38]  U. Dirnagl,et al.  IL-1β Stimulates COX-2 Dependent PGE2 Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells , 2011, PloS one.

[39]  G. Nappi,et al.  Activation of the transcription factor NF-kappaB in the nucleus trigeminalis caudalis in an animal model of migraine. , 2005, Neurotoxicology.

[40]  D. Mitsikostas,et al.  Receptor systems mediating c-fos expression within trigeminal nucleus caudalis in animal models of migraine , 2001, Brain Research Reviews.

[41]  M Diksic,et al.  Differences between males and females in rates of serotonin synthesis in human brain. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Michael E. Greenberg,et al.  Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.

[43]  L. Edvinsson Role of CGRP in Migraine. , 2019, Handbook of experimental pharmacology.

[44]  J. Wilson,et al.  Migraine , 2007, Annals of Internal Medicine.