Bitter taste of saccharin related to the genetic ability to taste the bitter substance 6-n-propylthiouracil.

Bitter taste thresholds for 6-n-propylthiouracil are bimodally distributed, dividing subjects into tasters and nontasters. Their taste worlds differ with regard to the sweetness of sucrose and saccharin and to the bitterness of saccharin. These differences suggest that nontasters tend to perceive less bitterness in saccharin at concentrations used in beverages.

[1]  J. C. Stevens,et al.  PTC taste blindness and the taste of caffeine , 1975, Nature.

[2]  D. Mcburney,et al.  Gustatory cross-adaptation: does a single mechanism code the salty taste? , 1969, Journal of experimental psychology.

[3]  A. Blakeslee.  Genetics of Sensory Thresholds: Taste for Phenyl Thio Carbamide. , 1932, Proceedings of the National Academy of Sciences of the United States of America.

[4]  G. B. West,et al.  Taste polymorphism to anetholtrithione and phenylthiocarbamate , 1967, Annals of human genetics.

[5]  D. Mcburney.  Magnitude estimation of the taste of sodium chloride after adaptation to sodium chloride. , 1966 .

[6]  A. Blakeslee,et al.  Genetics of Sensory Thresholds: Variations within Single Individuals in Taste Sensitivity for PTC. , 1935, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M. Nachman.  The inheritance of saccharin preference. , 1959, Journal of comparative and physiological psychology.

[8]  L. Bartoshuk.  NaCl thresholds in man: thresholds for water taste or NaCl taste? , 1974, Journal of comparative and physiological psychology.

[9]  S. S. Stevens.  Power‐Group Transformations under Glare, Masking, and Recruitment , 1966 .

[10]  J. Ganchrow,et al.  Neural correlates of gustatory intensity and quality. , 1970, Journal of neurophysiology.

[11]  J. Defries,et al.  Similar Polymorphism of Taste Sensitivity to PTC in Mice and Men , 1970, Nature.

[12]  C. P. Richter,et al.  PHENYLTHIOCARBAMIDE TASTE THRESHOLDS OF RATS AND HUMAN BEINGS , 1941 .