Urinary tract infection: is there a need for routine renal ultrasonography?

Aims: To assess the yield of routine renal ultrasound (RUS) in the management of young children hospitalised with first uncomplicated febrile urinary tract infection (UTI). Methods: All children aged 0–5 years who had been hospitalised over a two year period with first uncomplicated febrile UTI in a medium size institutional regional medical centre were included. Children with known urinary abnormalities and/or who had been treated with antibacterial agents within seven days before admission were excluded. All included children underwent renal ultrasonography during hospitalisation and voiding cystouretrography (VCUG) within 2–6 months. The yield of RUS was measured by its ability to detect renal abnormalities, its sensitivity, specificity, and positive and negative predictive values for detecting vesicoureteral reflux (VUR), and by its impact on UTI management. Results: Of 255 children that were included in the study, 33 children had mild to moderate renal pelvis dilatation on RUS suggesting VUR, of whom only nine had VUR on VCUG. On the other hand, in 36 children with VUR on VCUG the RUS was normal. The sensitivity, specificity, positive predictive value, and negative predictive value of abnormal RUS for detecting VUR were 17.7%, 87.6%, 23.5%, and 83.2% respectively. In none of the patients with abnormal RUS was a change in the management at or following hospitalisation needed. Conclusion: Results show that the yield of RUS to the management of children with first uncomplicated UTI is questionable.

[1]  S. Downs,et al.  Practice Parameter: The Diagnosis, Treatment, and Evaluation of the Initial Urinary Tract Infection in Febrile Infants and Young Children , 1999, Pediatrics.

[2]  A. Hoberman,et al.  Urinary tract infections in young febrile children. , 1997, The Pediatric infectious disease journal.

[3]  S. Mahant,et al.  Renal ultrasound findings and vesicoureteral reflux in children hospitalised with urinary tract infection , 2002, Archives of disease in childhood.

[4]  R. Kallen Imaging studies after a first febrile urinary tract infection in young children. , 2003, The New England journal of medicine.

[5]  R. L. Lebowitz,et al.  International system of radiographic grading of vesicoureteric reflux , 2006, Pediatric Radiology.

[6]  U. Alon,et al.  Should Renal Ultrasonography Be Done Routinely in Children with First Urinary Tract Infection? , 1999, Clinical pediatrics.

[7]  M. Goldman,et al.  Imaging after urinary tract infection in male neonates. , 2000, Pediatrics.

[8]  W. Mason Urinary tract infections in children: renal ultrasound evaluation. , 1984, Radiology.

[9]  J. Smellie,et al.  Urinary tract infection: a comparison of four methods of investigation , 1996, Pediatric Nephrology.

[10]  B. Maguire,et al.  Does routine ultrasound have a role in the investigation of children with urinary tract infection? , 1994, Clinical radiology.

[11]  U. Lindberg,et al.  Guidelines for management of children with urinary tract infection and vesico‐ureteric reflux. Recommendations from a Swedish state‐of‐the‐art conference , 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

[12]  A. Fretzayas,et al.  Sonography as a substitute for excretory urography in children with urinary tract infection. , 1985, AJR. American journal of roentgenology.