Sedative effects of the jasmine tea odor and (R)-(−)-linalool, one of its major odor components, on autonomic nerve activity and mood states

We investigated the effects of the odor of jasmine tea on autonomic nerve activity and mood states in a total of 24 healthy volunteers. We used the odor of jasmine tea at the lowest concentration that could be detected by each subject but that did not elicit any psychological effects. R–R intervals and the POMS test were measured before and after inhalation of the odors for 5 min. Both jasmine tea and lavender odors at perceived similar intensity caused significant decreases in heart rate and significant increases in spectral integrated values at high-frequency component in comparison with the control (P < 0.05). In the POMS tests, these odors produced calm and vigorous mood states. We also examined the effects of (R)-(−)-linalool, one of its major odor components, at the same concentration as in the tea, and (S)-(+)-linalool. Only (R)-(−)-linalool elicited a significant decrease in heart rate (P < 0.05) and an increase in high-frequency component in comparison with the controls, and produced calm and vigorous mood states. Thus, the low intensity of jasmine tea odor has sedative effects on both autonomic nerve activity and mood states, and (R)-(−)-linalool, one of its components, can mimic these effects.

[1]  M. Nagai,et al.  Pleasant odors attenuate the blood pressure increase during rhythmic handgrip in humans , 2000, Neuroscience Letters.

[2]  T. Aoki Effects of volatile compounds from leaf oil on blood pressure after exercising , 1994 .

[3]  M. Lis‐Balchin,et al.  A preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro. , 1997, Journal of ethnopharmacology.

[4]  P. Brauchli,et al.  Electrocortical and autonomic alteration by administration of a pleasant and an unpleasant odor. , 1995, Chemical senses.

[5]  T. Fushiki,et al.  Autonomic Nervous Responses According to Preference for the Odor of Jasmine Tea , 2003, Bioscience, biotechnology, and biochemistry.

[6]  W. Jäger,et al.  Stereoselective Metabolism of the Monoterpene Carvone by Rat and Human Liver Microsomes , 2000, The Journal of pharmacy and pharmacology.

[7]  P. Novak,et al.  Influence of respiration on heart rate and blood pressure fluctuations. , 1993, Journal of applied physiology.

[8]  G. Buchbauer,et al.  Percutaneous absorption of the montoterpene carvone: implication of stereoselective metabolism on blood levels , 2001, The Journal of pharmacy and pharmacology.

[9]  J. Chen The effects of Chinese tea on the occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine in rats. , 1992, Preventive medicine.

[10]  E. Elisabetsky,et al.  Effects of linalool on glutamatergic system in the rat cerebral cortex , 1995, Neurochemical Research.

[11]  G. Buchbauer,et al.  Aromatherapy—use of fragrances and essential oils as medicaments , 1994 .

[12]  D. Eckberg,et al.  Important influence of respiration on human R-R interval power spectra is largely ignored. , 1993, Journal of applied physiology.

[13]  J. S. Jellinek Psychodynamic odor effects and their mechanisms , 1997 .

[14]  H. Ehrlichman,et al.  Startle reflex modulation by pleasant and unpleasant odors in a between-subjects design. , 1997, Psychophysiology.

[15]  J. S. Jellinek Psychodynamic odor effects and their mechanisms : Failure to identify the mechanism can lead to faulty conclusions in odor studies , 1997 .

[16]  M. Lis‐Balchin,et al.  Studies on the mode of action of the essential oil of LavenderLavandula angustifolia P. Miller) , 1999, Phytotherapy research : PTR.

[17]  Schwartz Rk Olfaction and muscle activity: an EMG pilot study. , 1979 .

[18]  T. Moritani Sympatho-vagal activities of NIDDM patients during exercise as determined by heart rate spectral analysis , 1995 .

[19]  T. Matsuzaki,et al.  Detection and chemical identification of natural bio-antimutagens. A case of the green tea factor. , 1985, Mutation research.

[20]  J. Behan,et al.  An analysis of spontaneous human cortical EEG activity to odours , 1993 .

[21]  T. Hongratanaworakit,et al.  Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation. , 2001, Chemical senses.

[22]  H. Mukhtar,et al.  Interaction of epicatechins derived from green tea with rat hepatic cytochrome P-450. , 1988, Drug metabolism and disposition: the biological fate of chemicals.

[23]  Tyler S. Lorig,et al.  Human EEG and odor response , 1989, Progress in Neurobiology.

[24]  T. Moritani Comparison of sympatho-vagal function among diabetic patients, normal controls and endurance athletes by heart rate spectral analysis , 1993 .

[25]  Yuriko Ito,et al.  Identification of potent odorants in Chinese jasmine green tea scented with flowers of Jasminum sambac. , 2002, Journal of agricultural and food chemistry.

[26]  S. Torii,et al.  Contingent negative variation (CNV) and the psychological effects of odour , 1988 .

[27]  W. Jäger,et al.  Aromatherapy: Evidence for Sedative Effects of the Essential Oil of Lavender after Inhalation , 1991, Zeitschrift fur Naturforschung. C, Journal of biosciences.

[28]  M. Hardy,et al.  Replacement of drug treatment for insomnia by ambient odour , 1995, The Lancet.

[29]  Yasuo Ikeda,et al.  Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo. , 1997, Life sciences.

[30]  K. Fung,et al.  Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells. , 1997, Life sciences.

[31]  H. Shi,et al.  Antioxidative effect of polyphenol extract prepared from various Chinese teas. , 1992, Preventive medicine.

[32]  T. T. Yang,et al.  Hypocholesterolemic effects of Chinese tea. , 1997, Pharmacological research.

[33]  A. Dittmar,et al.  Odor hedonics: connection with emotional response estimated by autonomic parameters. , 1997, Chemical senses.

[34]  M. Laska,et al.  Enantioselectivity of odor perception in squirrel monkeys and humans. , 1999, The American journal of physiology.

[35]  M. Tanida,et al.  Effects of olfactory stimulation with jasmin and its component chemicals on the duration of pentobarbital-induced sleep in mice. , 1992, Life sciences.

[36]  W. Jäger,et al.  Fragrance compounds and essential oils with sedative effects upon inhalation. , 1993, Journal of pharmaceutical sciences.

[37]  Y. Saeki,et al.  The effect of foot-bath with or without the essential oil of lavender on the autonomic nervous system: a randomized trial. , 2000, Complementary therapies in medicine.

[38]  I Tomita,et al.  Antioxidative effects of black tea theaflavins and thearubigin on lipid peroxidation of rat liver homogenates induced by tert-butyl hydroperoxide. , 1994, Biological & pharmaceutical bulletin.