Symptomatic Patency Capsule Retention in Suspected Crohn's Disease.

The main limitation of capsule endoscopy is the risk of capsule retention. In patients with suspected Crohn's disease, however, this complication is rare, and if a small bowel stenosis is not reliably excluded, small bowel patency can be confirmed with the Pillcam patency capsule. We present two patients examined for suspected Crohn's disease who experienced significant symptoms from a retained patency capsule. Both patients had Crohn's disease located in the terminal ileum. In one patient, the patency capsule caused abdominal pain and vomiting and was visualized at magnetic resonance enterography 9 days after ingestion. Symptoms improved spontaneously. Another patient experienced small bowel perforation with severe peritonitis caused by an intact patency capsule wedged in a small bowel stricture. We conclude that the Pillcam patency capsule is an effective modality for securing small bowel patency prior to capsule endoscopy. However, it should be emphasized that delayed patency capsule degradation and symptomatic capsule retention is a rare but potentially severe complication which should be treated aggressively, either medically or endoscopically.

[1]  J. Romero-Vázquez,et al.  Patency and Agile capsules. , 2008, World journal of gastroenterology.

[2]  M. Crowell,et al.  Performance of the patency capsule compared with nonenteroclysis radiologic examinations in patients with known or suspected intestinal strictures. , 2011, Gastrointestinal endoscopy.

[3]  B. Lewis,et al.  ICCE consensus for capsule retention. , 2005, Endoscopy.

[4]  D. Morgan,et al.  Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy. , 2007, Gastrointestinal endoscopy.

[5]  E. Seidman,et al.  Use of patency capsule in patients with established Crohn’s disease , 2015, Endoscopy.

[6]  B. Lewis Expanding role of capsule endoscopy in inflammatory bowel disease. , 2008, World journal of gastroenterology.

[7]  Emanuele Rondonotti,et al.  Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline , 2015, Endoscopy.

[8]  A. Amiot,et al.  European evidence based consensus for endoscopy in inflammatory bowel disease. , 2013, Journal of Crohn's & colitis.

[9]  J. Kjeldsen,et al.  Capsule endoscopy for the diagnosis and follow up of Crohn’s disease: a comprehensive review of current status , 2016, Annals of gastroenterology.

[10]  J. A. Leighton,et al.  Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus , 2009, Endoscopy.

[11]  H Messmann,et al.    Clinical Experience with the PillCam Patency Capsule prior to Video Capsule Endoscopy: A Real-World Experience , 2016, Gastroenterology research and practice.