Receptors to Dolichos biflorus agglutinin. A new cell surface marker common to teratocarcinoma cells and preimplantation mouse embryos.

Dolichos biflorus agglutinin (DBA), a lectin specific to N-acetylgalactosamine residue, identifies cell surface markers on teratocarcinoma cells. These receptors are found in very limited types of adult tissues. In the present investigation, mouse embryos collected on day 1 (2-cell) to 3 (early blastocyst) were shown to be stained with FITC-conjugated DBA. Embryos homozygous for tw32 were also positively stained. These results suggest that receptors for DBA on preimplantation embryos include components distinct from Forssman, F9, and SSEA-1 antigens.

[1]  T. Muramatsu,et al.  Discrete Distribution of binding sites for Dolichos biflorus agglutinin (DBA) and for peanut agglutinin (PNA) in mouse organ tissues. , 1981, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[2]  T. Muramatsu,et al.  Receptors for Dolichos biflorus agglutinin on embryonal carcinoma cells. , 1981, Journal of biochemistry.

[3]  T. Muramatsu,et al.  Cell surface carbohydrates of embryonal carcinoma cells: Polysaccharidic side chains of F9 antigens and of receptors to two lectins, FBP and PNA , 1979, Cell.

[4]  D. Solter,et al.  Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[5]  P. Stern,et al.  Expression of a Forssman antigenic specificity in the preimplantation mouse embryo , 1978, Cell.

[6]  G. Galfré,et al.  Monoclonal antibodies as probes for differentiation and tumor-associated antigens: a Forssman specificity on teratocarcinoma stem cells , 1978, Cell.

[7]  N. Sharon,et al.  Interaction of peanut agglutinin, a lectin specific for nonreducing terminal D-galactosyl residues, with embryonal carcinoma cells. , 1977, Developmental biology.

[8]  Franclois Jacob Mouse Teratocarcinoma and Embryonic Antigens , 1977, Immunological reviews.

[9]  J. Guénet,et al.  Embryonal carcinoma antigen and the T/t locus of the mouse. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[10]  N. Sharon,et al.  Saccharides on teratocarcinoma cell plasma membranes. Their investigation with radioactively labelled lectins. , 1976, Biochimica et biophysica acta.

[11]  D. Bennett The T-locus of the mouse , 1975, Cell.

[12]  K. Artzt,et al.  Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[13]  K. Artzt,et al.  Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[14]  E. Kabat,et al.  Purification and characterization of a lectin (plant hemagglutinin) with blood group A specificity from Dolichos biflorus. , 1970, Biochemistry.