Multifactorial Involvement of Multidrug Resistance Protein, DNA Topoisomerase II and Glutathione/Glutathione‐S‐Transferase in NonP‐ Glycoprotein‐Mediated Multidrug Resistance in Human Bladder Cancer Cells

Background:

[1]  O. Yoshida,et al.  Expression of multidrug resistance-related genes (mdrl, MRP, GST-pi and DNA topoisomerase II) in urothelial cancers. , 1996, British journal of urology.

[2]  O. Yoshida,et al.  Expression patterns of multidrug-resistance (MDR1), multidrug resistance-associated protein (MRP),glutathione-S-transferase-pi (GST-pi) and DNA topoisomerase II (Topo II) genes in renal cell carcinomas and normal kidney. , 1996, The Journal of urology.

[3]  O. Yoshida,et al.  Comparison of multidrug resistance gene expression levels with malignant potentials and influence of chemotherapy in urothelial cancers. , 1995, International journal of urology : official journal of the Japanese Urological Association.

[4]  M. Kuwano,et al.  Non‐P‐glycoprotein‐mediated Atypical Multidrug Resistance in a Human Bladder Cancer Cell Line , 1995, Japanese journal of cancer research : Gann.

[5]  Wun-Jae Kim,et al.  Multidrug Resistance‐associated Protein‐mediated Multidrug Resistance Modulated by Cyclosporin A in a Human Bladder Cancer Cell Line , 1995, Japanese journal of cancer research : Gann.

[6]  M. Kuwano,et al.  Reversal by a dihydropyridine derivative of non-P-glycoprotein-mediated multidrug resistance in etoposide-resistant human prostatic cancer cell line. , 1995, The Journal of urology.

[7]  F. Baas,et al.  The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[8]  K. Kohno,et al.  Increased expression of DNA topoisomerase I gene and collateral sensitivity to camptothecin in human cisplatin-resistant bladder cancer cells. , 1994, Cancer research.

[9]  H. Takano,et al.  Increased phosphorylation of DNA topoisomerase II in etoposide-resistant mutants of human cancer KB cells. , 1991, Cancer research.

[10]  R. Weichselbaum,et al.  Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance. , 1991, Cancer research.

[11]  D. Waxman,et al.  Glutathione S-transferases: role in alkylating agent resistance and possible target for modulation chemotherapy--a review. , 1990, Cancer research.

[12]  H. Takano,et al.  Reduction of drug accumulation and DNA topoisomerase II activity in acquired teniposide-resistant human cancer KB cell lines. , 1990, Cancer research.

[13]  A. Gazdar,et al.  Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[14]  S. de Jong,et al.  Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line. , 1990, Cancer research.

[15]  B. Teicher,et al.  Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance. , 1989, Cancer research.

[16]  D. Siemann,et al.  A study of the mechanism of resistance to Adriamycin in vivo. Glutathione metabolism, P-glycoprotein expression, and drug transport. , 1989, Biochemical pharmacology.

[17]  K. Bhalla,et al.  Role of glutathione and dependent enzymes in anthracycline-resistant HL60/AR cells. , 1989, Cancer research.

[18]  I. Pastan,et al.  The multidrug transporter, a double-edged sword. , 1988, The Journal of biological chemistry.

[19]  R. Kramer,et al.  Role of the glutathione redox cycle in acquired and de novo multidrug resistance. , 1988, Science.

[20]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[21]  J. Endicott,et al.  Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance , 1986, Nature.

[22]  A. Tulpule,et al.  Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells. , 1986, The Journal of biological chemistry.

[23]  Michael M. Gottesman,et al.  Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells , 1986, Cell.

[24]  M. Winker,et al.  Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion. , 1985, Biochemical pharmacology.

[25]  I. Pastan,et al.  Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines. , 1985, Cancer research.

[26]  C. Nathan,et al.  Glutathione metabolism as a determinant of therapeutic efficacy: a review. , 1984, Cancer research.

[27]  B. Aggarwal,et al.  The synergistic anti-proliferative effect of gamma-interferon and human lymphotoxin. , 1984, Journal of immunology.

[28]  J. Riordan,et al.  Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein. , 1983, Cancer research.

[29]  A. Meister.  Selective modification of glutathione metabolism. , 1983, Science.

[30]  L. Liu,et al.  A homogeneous type II DNA topoisomerase from HeLa cell nuclei. , 1981, The Journal of biological chemistry.

[31]  P. T. Englund,et al.  Decatenation of kinetoplast DNA by topoisomerases. , 1980, The Journal of biological chemistry.

[32]  R. Johnson,et al.  Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia. , 1979, Cancer research.

[33]  W B Jakoby,et al.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. , 1974, The Journal of biological chemistry.

[34]  F. Tietze.  Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. , 1969, Analytical biochemistry.

[35]  W. Valentine,et al.  Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. , 1967, The Journal of laboratory and clinical medicine.

[36]  K. Cowan,et al.  Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. , 1994, Cancer research.