Impact of glyphosate and its formulation Roundup® on stallion spermatozoa

[1]  M. C. Gil,et al.  An integrated overview on the regulation of sperm metabolism (glycolysis-Krebs cycle-oxidative phosphorylation). , 2021, Animal reproduction science.

[2]  D. Martín-Hidalgo,et al.  Impaired mammalian sperm function and lower phosphorylation signaling caused by the herbicide Roundup® Ultra Plus are due to its surfactant component. , 2021, Theriogenology.

[3]  Yaping Jin,et al.  Glyphosate exposure attenuates testosterone synthesis via NR1D1 inhibition of StAR expression in mouse Leydig cells. , 2021, The Science of the total environment.

[4]  F. Peña,et al.  The inhibition of spermatic cystine/glutamate antiporter xCT (SLC7A11) influences the ability of cryopreserved stallion sperm to bind to heterologous zonae pellucidae. , 2021, Theriogenology.

[5]  S. Lorenzetti,et al.  Herbicides glyphosate and glufosinate ammonium negatively affect human sperm mitochondria respiration efficiency. , 2020, Reproductive toxicology.

[6]  G. Galeati,et al.  Glyphosate and its formulation Roundup impair pig oocyte maturation , 2020, Scientific Reports.

[7]  M. Yeste,et al.  Effects of Roundup and its main component, glyphosate, upon mammalian sperm function and survival , 2020, Scientific Reports.

[8]  H. Kohan-Ghadr,et al.  Glyphosate Induces Metaphase II Oocyte Deterioration and Embryo Damage by Zinc Depletion and Overproduction of Reactive Oxygen Species. , 2020, Toxicology.

[9]  P. Steinberg,et al.  Glyphosate and AMPA levels in human urine samples and their correlation with food consumption: results of the cross-sectional KarMeN study in Germany , 2020, Archives of Toxicology.

[10]  H. Fu,et al.  Toxic effects of glyphosate on intestinal morphology, antioxidant capacity and barrier function in weaned piglets. , 2020, Ecotoxicology and environmental safety.

[11]  D. Bucci,et al.  Seasonal changes in ROS concentrations and sperm quality in unfrozen and frozen-thawed stallion semen. , 2019, Theriogenology.

[12]  Xizeng Feng,et al.  The toxic effects and possible mechanisms of glyphosate on mouse oocytes. , 2019, Chemosphere.

[13]  A. Bassols,et al.  Total and specific activities of superoxide dismutase (SOD) in seminal plasma are related with the cryotolerance of jackass spermatozoa. , 2019, Cryobiology.

[14]  P. Roman,et al.  GUT MICROBIOTA AND NEUROLOGICAL EFFECTS OF GLYPHOSATE. , 2019, Neurotoxicology.

[15]  Elaine Manoela Porto Amorim,et al.  Glyphosate-based herbicide exposure during pregnancy and lactation malprograms the male reproductive morphofunction in F1 offspring , 2019, Journal of Developmental Origins of Health and Disease.

[16]  S. Swan,et al.  The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system , 2019, Environmental Health.

[17]  B. Jégou,et al.  Perinatal Exposure to Glyphosate and a Glyphosate-Based Herbicide Affect Spermatogenesis in Mice. , 2019, Toxicological sciences : an official journal of the Society of Toxicology.

[18]  G. Séralini,et al.  Formulants of glyphosate-based herbicides have more deleterious impact than glyphosate on TM4 Sertoli cells. , 2018, Toxicology in vitro : an international journal published in association with BIBRA.

[19]  M. Yeste,et al.  Combined effects of resveratrol and epigallocatechin-3-gallate on post thaw boar sperm and IVF parameters. , 2018, Theriogenology.

[20]  G. Anifandis,et al.  The Effect of Glyphosate on Human Sperm Motility and Sperm DNA Fragmentation , 2018, International journal of environmental research and public health.

[21]  Jianzhong Hu,et al.  The Ramazzini Institute 13-week pilot study on glyphosate and Roundup administered at human-equivalent dose to Sprague Dawley rats: effects on the microbiome , 2018, Environmental Health.

[22]  G. Séralini,et al.  Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides , 2017, Toxicology reports.

[23]  F. Zhang,et al.  Effects of glyphosate exposure on sperm concentration in rodents: A systematic review and meta-analysis. , 2017, Environmental toxicology and pharmacology.

[24]  M. Zeng,et al.  In vitro cytotoxicity assessment of roundup (glyphosate) in L-02 hepatocytes , 2017, Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.

[25]  A. Psarra,et al.  The In Vitro Impact of the Herbicide Roundup on Human Sperm Motility and Sperm Mitochondria , 2016, Toxics.

[26]  G. Galeati,et al.  Epigallocatechin‐3‐gallate (EGCG) and green tea polyphenols do not improve stallion semen parameters during cooling at 4°C , 2017, Reproduction in domestic animals = Zuchthygiene.

[27]  Chunmei Li,et al.  Effect of glyphosate on reproductive organs in male rat. , 2016, Acta histochemica.

[28]  R. Aitken,et al.  The Impact of Sperm Metabolism during In Vitro Storage: The Stallion as a Model , 2016, BioMed research international.

[29]  S. Rosso,et al.  Neuronal development and axon growth are altered by glyphosate through a WNT non-canonical signaling pathway. , 2016, Neurotoxicology.

[30]  J. Rodríguez-Gil,et al.  Current knowledge on boar sperm metabolism: Comparison with other mammalian species. , 2016, Theriogenology.

[31]  F. Peña,et al.  Inhibition of Mitochondrial Complex I Leads to Decreased Motility and Membrane Integrity Related to Increased Hydrogen Peroxide and Reduced ATP Production, while the Inhibition of Glycolysis Has Less Impact on Sperm Motility , 2015, PloS one.

[32]  B. Ball,et al.  The Impact of Reproductive Technologies on Stallion Mitochondrial Function. , 2015, Reproduction in domestic animals = Zuchthygiene.

[33]  R. Aitken,et al.  The Paradoxical Relationship Between Stallion Fertility and Oxidative Stress1 , 2014, Biology of reproduction.

[34]  G. Séralini,et al.  An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality. , 2014, Environmental toxicology and pharmacology.

[35]  M. Yeste,et al.  Supplementing culture and vitrification-warming media with l-ascorbic acid enhances survival rates and redox status of IVP porcine blastocysts via induction of GPX1 and SOD1 expression. , 2014, Cryobiology.

[36]  G. Chaufan,et al.  Glyphosate Commercial Formulation Causes Cytotoxicity, Oxidative Effects, and Apoptosis on Human Cells , 2014, International journal of toxicology.

[37]  M. Yeste,et al.  Oligomycin A-induced inhibition of mitochondrial ATP-synthase activity suppresses boar sperm motility and in vitro capacitation achievement without modifying overall sperm energy levels. , 2014, Reproduction, fertility, and development.

[38]  A. Zamoner,et al.  Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells. , 2013, Free radical biology & medicine.

[39]  R. Mesnage,et al.  Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. , 2013, Toxicology.

[40]  J. Satayavivad,et al.  Glyphosate induces human breast cancer cells growth via estrogen receptors. , 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[41]  R. Mesnage,et al.  A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels. , 2012, Toxicology in vitro : an international journal published in association with BIBRA.

[42]  Ho-Yeon Song,et al.  Cellular Toxicity of Surfactants Used as Herbicide Additives , 2011, Journal of Korean medical science.

[43]  M. T. Nunes,et al.  Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression , 2012, Archives of Toxicology.

[44]  C. Vallorani,et al.  GLUTs and mammalian sperm metabolism. , 2011, Journal of andrology.

[45]  J. Elizalde,et al.  Diabetic Retinopathy Is Associated with Decreased Tyrosine Nitrosylation of Vitreous Interleukins IL-1α, IL-1β, and IL-7 , 2011, Ophthalmic Research.

[46]  R. M. Romano,et al.  Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology , 2010, Archives of Toxicology.

[47]  C. Colás,et al.  Changes in calmodulin immunocytochemical localization associated with capacitation and acrosomal exocytosis of ram spermatozoa. , 2009, Theriogenology.

[48]  N. Bénachour,et al.  Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. , 2009, Chemical research in toxicology.

[49]  P. Dalsenter,et al.  Pre- and postnatal toxicity of the commercial glyphosate formulation in Wistar rats , 2007, Archives of Toxicology.

[50]  F. Peixoto.  Comparative effects of the Roundup and glyphosate on mitochondrial oxidative phosphorylation. , 2005, Chemosphere.

[51]  J. Rodríguez-Gil,et al.  Identification of sperm subpopulations with specific motility characteristics in stallion ejaculates. , 2003, Theriogenology.

[52]  D. Stocco,et al.  Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression. , 2000, Environmental health perspectives.

[53]  R Kroes,et al.  Safety evaluation and risk assessment of the herbicide Roundup and its active ingredient, glyphosate, for humans. , 2000, Regulatory toxicology and pharmacology : RTP.

[54]  C. Dinney,et al.  Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[55]  R. Kenney,et al.  Minimal contamination techniques for breeding mares: techniques and preliminary findings , 1975 .