Association Between Consecutive Ambient Air Pollution and Chronic Obstructive Pulmonary Disease Hospitalization: Time Series Study During 2015-2017 in Chengdu China

This paper investigates the association between consecutive ambient air pollution and Chronic Obstructive Pulmonary Disease (COPD) hospitalization in Chengdu China. The three-year (2015-2017) time series data for both ambient air pollutant concentrations and COPD hospitalizations in Chengdu are approved for the study. The big data statistic analysis shows that Air Quality Index (AQI) exceeded the lighted air polluted level in Chengdu region are mainly attributed to particulate matters (i.e., PM2.5 and PM10). The time series study for consecutive ambient air pollutant concentrations reveal that AQI, PM2.5, and PM10 are significantly positive correlated, especially when the number of consecutive polluted days is greater than nine days. The daily COPD hospitalizations for every 10 µg/m3 increase in PM2.5 and PM10 indicate that consecutive ambient air pollution can lead to an appearance of an elevation of COPD admissions, and also present that dynamic responses before and after the peak admission are different. Support Vector Regression (SVR) is then used to describe the dynamics of COPD hospitalizations to consecutive ambient air pollution. These findings will be further developed for region specific, hospital early notifications of COPD in responses to consecutive ambient air pollution.

[1]  Hong Qiu,et al.  Season and humidity dependence of the effects of air pollution on COPD hospitalizations in Hong Kong , 2013 .

[2]  Wei Gao,et al.  Short-term associations between size-fractionated particulate air pollution and COPD mortality in Shanghai, China. , 2020, Environmental Pollution.

[3]  Xian Wen Sun,et al.  The cumulative effect of air pollutants on the acute exacerbation of COPD in Shanghai, China. , 2018, The Science of the total environment.

[4]  Qiang Zou,et al.  Polycyclic aromatic hydrocarbons are associated with increased risk of chronic obstructive pulmonary disease during haze events in China. , 2017, The Science of the total environment.

[5]  Po-Hao Feng,et al.  Chronic obstructive pulmonary disease patients have a higher risk of occurrence of pneumonia by air pollution. , 2019, The Science of the total environment.

[6]  Pei Gao,et al.  Chronic obstructive pulmonary disease in China: a nationwide prevalence study , 2018, The Lancet Respiratory Medicine.

[7]  Jin-Nan Wang,et al.  China tackles the health effects of air pollution , 2013, The Lancet.

[8]  Hang Qiu,et al.  Attributable risk of hospital admissions for overall and specific mental disorders due to particulate matter pollution: A time‐series study in Chengdu, China , 2019, Environmental research.

[9]  W. MacNee,et al.  Mechanism of lung injury caused by PM10 and ultrafine particles with special reference to COPD , 2003, European Respiratory Journal.

[10]  Peng Yin,et al.  A Subnational Analysis of Mortality and Prevalence of COPD in China From 1990 to 2013: Findings From the Global Burden of Disease Study 2013. , 2016, Chest.

[11]  Wenjun Ma,et al.  The attributable risk of chronic obstructive pulmonary disease due to ambient fine particulate pollution among older adults. , 2018, Environment international.

[12]  J. Halonen,et al.  Urban air pollution, and asthma and COPD hospital emergency room visits , 2008, Thorax.

[13]  Hang Qiu,et al.  Risks of hospital admissions from a spectrum of causes associated with particulate matter pollution. , 2019, The Science of the total environment.

[14]  Hang Qiu,et al.  The Burden of COPD Morbidity Attributable to the Interaction between Ambient Air Pollution and Temperature in Chengdu, China , 2018, International journal of environmental research and public health.