Diagnosis and treatment of temporomandibular disorders: an ethical analysis of current practices.

The defining characteristic of a profession - and especially a health-care profession - is that the behaviour of its members is proscribed by a formal code of ethics. The main purpose of such codes is to guide practitioners' interactions with patients, assuring that patient interests are protected. In other words, the ethical code requires practitioners to place their patients' needs for proper diagnosis and appropriate treatment ahead of their own needs for income and advancement. The dental profession has a code of ethics that was developed by the American Dental Association many years ago; in most clinical situations, determination of proper behaviour is self-evident. However, the field of temporoman-dibular disorders (TMDs) has been the subject of considerable controversy for over half a century, and many people have argued that this makes it impossible to evaluate various approaches to treatment of TMDs within an ethical framework. In this article, the authors argue that the large volume of scientific evidence in the contemporary TMD literature provides an ethical framework for the diagnosis and treatment of patients with TMDs within a biopsychosocial medical model. They present a summary of the research with contemporary scientific integrity, which has produced that information over a period of many years. Based on that research, they conclude that dentists may provide conservative and reversible treatments that will be successful for most TMDs and in doing so will comply with the profession's code of ethics. Conversely, the authors claim that those dentists who continue to follow the older mechanistic models of TMD aetiology and treatment are not only out of step scientifically, but are placing their patients' welfare at risk by providing unnecessary irreversible bite-changing and jaw-repositioning interventions. Therefore, debate of these issues should not be solely focused on scientific merit, but also upon the compelling ethical obligations that dentists have as a result of the contemporary scientific literature regarding TMDs.

[1]  G. Carlsson,et al.  Need for occlusal therapy and prosthodontic treatment in the management of temporomandibular disorders. Part I. Occlusal interferences and occlusal adjustment. , 2000, Journal of oral rehabilitation.

[2]  D. Laskin,et al.  Long-term evaluation of treatment for myofascial pain-dysfunction syndrome: a comparative analysis. , 1983, Journal of the American Dental Association.

[3]  S. Cunningham,et al.  Orthognathic treatment and temporomandibular disorders: a systematic review. Part 2. Signs and symptoms and meta-analyses. , 2009, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

[4]  N.D. Mohl,et al.  Reliability and Validity of Diagnostic Modalities for Temporomandibular Disorders , 1993, Advances in dental research.

[5]  A. Glaros,et al.  Electromyographic data from TMD patients with myofascial pain and from matched control subjects: evidence for statistical, not clinical, significance. , 1997, Journal of orofacial pain.

[6]  S. Dworkin,et al.  The efficacy of traditional, low-cost and nonsplint therapies for temporomandibular disorder: a randomized controlled trial. , 2006, Journal of the American Dental Association.

[7]  D. Laskin,et al.  Technological Methods in the Diagnosis and Treatment of Temporomandibular Disorders , 1990, International Journal of Technology Assessment in Health Care.

[8]  P. Koidis,et al.  Effectiveness of conservative treatment for craniomandibular disorders: a 2-year longitudinal study. , 1994, Journal of orofacial pain.

[9]  D. Laskin,et al.  Temporomandibular Disorders: An Evidence-Based Approach to Diagnosis and Treatment , 2006, Physical Therapy.

[10]  S. Sato,et al.  Long-term changes in clinical signs and symptoms and disc position and morphology in patients with nonreducing disc displacement in the temporomandibular joint. , 1999, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[11]  D. Laskin Temporomandibular disorders: the past, present, and future , 2007, Odontology.

[12]  D. Manfredini,et al.  Ultrasonography of the temporomandibular joint: a literature review. , 2009, International journal of oral and maxillofacial surgery.

[13]  T. Beauchamp,et al.  Principles of biomedical ethics , 1991 .

[14]  G. Carlsson,et al.  A longitudinal epidemiologic study of signs and symptoms of temporomandibular disorders from 15 to 35 years of age. , 2000, Journal of orofacial pain.

[15]  J. P. Lund,et al.  An assessment of the efficacy of physical therapy and physical modalities for the control of chronic musculoskeletal pain , 1997, Pain.

[16]  R. Malow,et al.  Effects of biofeedback and psychotherapy on patients with myofascial pain dysfunction who are nonresponsive to conventional treatments. , 1987 .

[17]  D. Laskin,et al.  Long-term status of TMJ clicking in patients with myofascial pain and dysfunction. , 1988, Journal of the American Dental Association.

[18]  M. Rohlin,et al.  The efficacy of magnetic resonance imaging in the diagnosis of degenerative and inflammatory temporomandibular joint disorders: a systematic literature review. , 2006, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[19]  G. Clark,et al.  Guidelines for the examination and diagnosis of temporomandibular disorders. , 1989, Journal of craniomandibular disorders : facial & oral pain.

[20]  P. Conti,et al.  The treatment of painful temporomandibular joint clicking with oral splints: a randomized clinical trial. , 2006, Journal of the American Dental Association.

[21]  J. Okeson,et al.  Long-term results of treatment for temporomandibular disorders: an evaluation by patients. , 1986, Journal of the American Dental Association.

[22]  A. Jokstad,et al.  Clinical comparison between two different splint designs for temporomandibular disorder therapy , 2005, Acta odontologica Scandinavica.

[23]  Laxmaiah Manchikanti,et al.  Evidence-based medicine, systematic reviews, and guidelines in interventional pain management, part I: introduction and general considerations. , 2008, Pain physician.

[24]  E. Ekberg,et al.  Treatment outcome of appliance therapy in temporomandibular disorder patients with myofascial pain after 6 and 12 months , 2004, Acta odontologica Scandinavica.

[25]  J. P. Lund,et al.  The efficacy of oral splints in the treatment of myofascial pain of the jaw muscles: a controlled clinical trial , 1994, Pain.

[26]  A. Pullinger,et al.  Quantification and validation of predictive values of occlusal variables in temporomandibular disorders using a multifactorial analysis. , 2000, The Journal of prosthetic dentistry.

[27]  R. Dionne,et al.  National Institutes of Health Technology Assessment Conference Statement : Management of Temporomandibular Disorders, April 29-may 1, 1996 , 1997 .

[28]  G. Makoul,et al.  Defining Professionalism From the Perspective of Patients, Physicians, and Nurses , 2009, Academic medicine : journal of the Association of American Medical Colleges.

[29]  G. Perinetti,et al.  Posturography as a diagnostic aid in dentistry: a systematic review. , 2009, Journal of oral rehabilitation.

[30]  S. Cohen Follow-up evaluation of 105 patients with myofascial pain-dysfunction syndrome. , 1978, Journal of the American Dental Association.

[31]  M. Schmitter,et al.  Validity of temporomandibular disorder examination procedures for assessment of temporomandibular joint status. , 2008, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

[32]  W. Solberg,et al.  Oral health status in the United States: temporomandibular disorders. , 1985, Journal of dental education.

[33]  R. Gatchel,et al.  Cost-effectiveness of treatments for temporomandibular disorders: biopsychosocial intervention versus treatment as usual. , 2007, Journal of the American Dental Association.

[34]  J. Fricton Current evidence providing clarity in management of temporomandibular disorders: summary of a systematic review of randomized clinical trials for intra-oral appliances and occlusal therapies. , 2006, The journal of evidence-based dental practice.

[35]  A. Michelotti,et al.  Home-exercise regimes for the management of non-specific temporomandibular disorders. , 2005, Journal of oral rehabilitation.

[36]  M. Dolwick,et al.  Arthrocentesis for the treatment of temporomandibular joint closed lock: a review article. , 2007, International journal of oral and maxillofacial surgery.

[37]  T. List,et al.  Management of TMD: evidence from systematic reviews and meta-analyses. , 2010, Journal of oral rehabilitation.

[38]  Tomas Magnusson,et al.  A 20-year follow-up of signs and symptoms of temporomandibular disorders and malocclusions in subjects with and without orthodontic treatment in childhood. , 2009, The Angle orthodontist.

[39]  E. Pellegrino,et al.  Professionalism, profession and the virtues of the good physician. , 2002, The Mount Sinai journal of medicine, New York.

[40]  K. Motegi,et al.  Natural course of disc displacement with reduction of the temporomandibular joint: changes in clinical signs and symptoms. , 2003, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[41]  G. Lavigne,et al.  Oral splints: the crutches for temporomandibular disorders and bruxism? , 1998, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[42]  D. Manfredini,et al.  Temporomandibular joint total replacement prosthesis: current knowledge and considerations for the future. , 2008, International journal of oral and maxillofacial surgery.

[43]  J. Orthlieb,et al.  Recommendations by the EACD for examination, diagnosis, and management of patients with temporomandibular disorders and orofacial pain by the general dental practitioner. , 2008, Journal of orofacial pain.

[44]  G. Carlsson,et al.  A prospective investigation over two decades on signs and symptoms of temporomandibular disorders and associated variables. A final summary , 2005, Acta odontologica Scandinavica.

[45]  P. Robinson,et al.  Occlusal adjustment for treating and preventing temporomandibular joint disorders. , 2004, Journal of oral rehabilitation.

[46]  G. Klasser,et al.  Oral appliances in the management of temporomandibular disorders. , 2009, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[47]  Howard S. Smith,et al.  Evidence-Based Medicine Evidence-Based Medicine , Systematic Reviews , and Guidelines in Interventional Pain Management : Part 6 . Systematic Reviews and Meta-Analyses of Observational Studies , 2022 .

[48]  Joel Lexchin,et al.  Those Who Have the Gold Make the Evidence: How the Pharmaceutical Industry Biases the Outcomes of Clinical Trials of Medications , 2011, Science and Engineering Ethics.

[49]  Jian Wang,et al.  The possible role of estrogen in the incidence of temporomandibular disorders. , 2008, Medical hypotheses.

[50]  C. McNeill,et al.  Management of temporomandibular disorders: concepts and controversies. , 1997, The Journal of prosthetic dentistry.

[51]  E. Pellegrino Toward a reconstruction of medical morality: the primacy of the act of profession and the fact of illness. , 1979, The Journal of medicine and philosophy.

[52]  G. Carlsson,et al.  Predictors of signs and symptoms of temporomandibular disorders: a 20-year follow-up study from childhood to adulthood , 2002, Acta odontologica Scandinavica.

[53]  S. Dworkin,et al.  Diagnostic studies of temporomandibular disorders: challenges from an epidemiologic perspective. , 1990, Anesthesia progress.

[54]  C. Greene Temporomandibular disorders in the geriatric population. , 1994, The Journal of prosthetic dentistry.

[55]  G. Carlsson,et al.  Analysis of factors influencing the long-term effect of treatment of TMJ-pain dysfunction. , 1984, Journal of oral rehabilitation.

[56]  J. Okeson Orofacial pain : guidelines for assessment, diagnosis, and management , 1996 .

[57]  U. John,et al.  Association of malocclusion and functional occlusion with subjective symptoms of TMD in adults: results of the Study of Health in Pomerania (SHIP). , 2009, The Angle orthodontist.

[58]  S. Harris,et al.  A systematic review of the effectiveness of exercise, manual therapy, electrotherapy, relaxation training, and biofeedback in the management of temporomandibular disorder. , 2006, Physical therapy.

[59]  P. Westesson,et al.  Condyle position in the temporomandibular joint. Comparison between asymptomatic volunteers with normal disk position and patients with disk displacement. , 1995, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[60]  C. Greene Managing the care of patients with temporomandibular disorders: a new guideline for care. , 2010, Journal of the American Dental Association.

[61]  S. Minagi,et al.  Palpation of the lateral pterygoid region in TMD--where is the evidence? , 2001, Journal of dentistry.

[62]  J. Rugh,et al.  Temporomandibular disorders: diagnosis, management, education, and research. , 1990, Journal of the American Dental Association.

[63]  Y. González,et al.  Technological devices in the diagnosis of temporomandibular disorders. , 2008, Oral and maxillofacial surgery clinics of North America.

[64]  A. Glenny,et al.  Stabilization splint therapy for the treatment of temporomandibular myofascial pain: a systematic review. , 2005, Journal of dental education.

[65]  D. Vallon,et al.  The efficacy of appliance therapy in patients with temporomandibular disorders of mainly myogenous origin. A randomized, controlled, short-term trial. , 2003, Journal of orofacial pain.

[66]  R. Ohrbach,et al.  Five-year outcomes in TMD: relationship of changes in pain to changes in physical and psychological variables , 1998, Pain.

[67]  L. Bondemark,et al.  Alterations of temporomandibular disorders before and after orthognathic surgery: a systematic review. , 2007, The Angle orthodontist.

[68]  E. Kalso,et al.  Occlusal treatments in temporomandibular disorders: a qualitative systematic review of randomized controlled trials , 1999, PAIN®.

[69]  D. Laskin,et al.  Splint therapy for the myofascial pain--dysfunction (MPD) syndrome: a comparative study. , 1972, Journal of the American Dental Association.

[70]  E. Kalso,et al.  Application of principles of evidence-based medicine to occlusal treatment for temporomandibular disorders: are there lessons to be learned? , 2004, Journal of orofacial pain.

[71]  D. Laskin,et al.  Long-term evaluation of conservative treatment for myofascial pain-dysfunction syndrome. , 1974, Journal of the American Dental Association.

[72]  G. Carlsson,et al.  A cross-sectional and longitudinal study of craniomandibular dysfunction in an elderly population. , 1992, Journal of craniomandibular disorders : facial & oral pain.

[73]  L. Bondemark,et al.  TMD in relation to malocclusion and orthodontic treatment. , 2007, The Angle orthodontist.

[74]  P Kemppainen,et al.  Review of clinical EMG studies related to muscle and occlusal factors in healthy and TMD subjects. , 2007, Journal of oral rehabilitation.

[75]  M. Rohlin,et al.  Relationship between clinical and magnetic resonance imaging diagnoses and findings in degenerative and inflammatory temporomandibular joint diseases: a systematic literature review. , 2009, Journal of orofacial pain.

[76]  P. Westesson,et al.  Natural Course of Untreated Symptomatic Temporomandibular Joint Disc Displacement without Reduction , 1998, Journal of dental research.

[77]  G. Clark,et al.  A review of temporomandibular disorder diagnostic techniques. , 2001, The Journal of prosthetic dentistry.

[78]  R. Gatchel,et al.  Efficacy of an early intervention for patients with acute temporomandibular disorder-related pain: a one-year outcome study. , 2006, Journal of the American Dental Association.

[79]  D. Manfredini,et al.  Muscle relaxants in the treatment of myofascial face pain. A literature review. , 2004, Minerva Stomatologica.

[80]  R. Ow,et al.  Symptoms of craniomandibular disorder among elderly people. , 1995, Journal of oral rehabilitation.

[81]  W. Mccall,et al.  Conventional and nonoccluding splint therapy compared for patients with myofascial pain dysfunction syndrome. , 1987, General dentistry.

[82]  Mohammed A Q Al-Saleh,et al.  Electromyography in diagnosing temporomandibular disorders. , 2012, Journal of the American Dental Association.

[83]  C. Stohler,et al.  On the management of temporomandibular disorders: a plea for a low-tech, high-prudence therapeutic approach. , 1999, Journal of orofacial pain.

[84]  Raymond A. Dionne,et al.  Temporomandibular disorders and related pain conditions , 1995 .

[85]  M. Warren,et al.  Temporomandibular Disorders and Hormones in Women , 2001, Cells Tissues Organs.

[86]  G. Clark,et al.  Guidelines for the treatment of temporomandibular disorders. , 1990, Journal of craniomandibular disorders : facial & oral pain.

[87]  D. Manfredini,et al.  Kinesiographic recordings of jaw movements are not accurate to detect magnetic resonance-diagnosed temporomandibular joint (TMJ) effusion and disk displacement: findings from a validation study. , 2012, Oral surgery, oral medicine, oral pathology and oral radiology.

[88]  B. Stegenga,et al.  Radiographic signs of temporomandibular joint osteoarthrosis and internal derangement 30 years after nonsurgical treatment. , 1995, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[89]  G. Clark,et al.  The validity and utility of disease detection methods and of occlusal therapy for temporomandibular disorders. , 1997, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[90]  G. Clark,et al.  Predicting the outcome of a physical medicine treatment for temporomandibular disorder patients. , 2009, Journal of orofacial pain.

[91]  R. Wassell,et al.  The treatment of temporomandibular disorders with stabilizing splints in general dental practice: one-year follow-up. , 2006, Journal of the American Dental Association.

[92]  D. Manfredini,et al.  Agreement between Research Diagnostic Criteria for Temporomandibular Disorders and magnetic resonance diagnoses of temporomandibular disc displacement in a patient population. , 2008, International journal of oral and maxillofacial surgery.

[93]  F. Bosman,et al.  Interexaminer reliability of six orthopaedic tests in diagnostic subgroups of craniomandibular disorders. , 1994, Journal of oral rehabilitation.

[94]  H. Schindler,et al.  Is there a superiority of multimodal as opposed to simple therapy in patients with temporomandibular disorders? A qualitative systematic review of the literature. , 2007, Clinical oral implants research.

[95]  R. Ohrbach,et al.  JOR-CORE recommendations on rehabilitation of temporomandibular disorders. , 2010, Journal of oral rehabilitation.

[96]  J. Türp,et al.  Efficacy of stabilization splints for the management of patients with masticatory muscle pain: a qualitative systematic review , 2004, Clinical Oral Investigations.

[97]  T. List,et al.  Pharmacologic interventions in the treatment of temporomandibular disorders, atypical facial pain, and burning mouth syndrome. A qualitative systematic review. , 2004, Journal of orofacial pain.

[98]  S. Dworkin,et al.  A randomized clinical trial using research diagnostic criteria for temporomandibular disorders-axis II to target clinic cases for a tailored self-care TMD treatment program. , 2002, Journal of orofacial pain.

[99]  D. Magee,et al.  A systematic review of the effectiveness of physical therapy interventions for temporomandibular disorders. , 2006, Physical therapy.

[100]  S. Minagi,et al.  Is the posterior belly of the digastric muscle palpable? A qualitative systematic review of the literature , 2005, Clinical anatomy.

[101]  H. Yatani,et al.  Randomized Controlled Evaluation of Non-surgical Treatments for Temporomandibular Joint Anterior Disk Displacement without Reduction , 2001, Journal of dental research.

[102]  D. Laskin,et al.  Temporomandibular Disorders: Moving from a Dentally Based to a Medically Based Model , 2000, Journal of dentistry research.

[103]  B. Schouten,et al.  Information and Participation Preferences of Dental Patients , 2004, Journal of dental research.

[104]  J. Türp,et al.  The NTI-tss device for the therapy of bruxism, temporomandibular disorders, and headache – Where do we stand? A qualitative systematic review of the literature , 2008, BMC oral health.

[105]  G. Carlsson,et al.  Long-term results of treatment for temporomandibular joint pain-dysfunction. , 1983, The Journal of prosthetic dentistry.

[106]  U. John,et al.  Association of malocclusion and functional occlusion with signs of temporomandibular disorders in adults: results of the population-based study of health in Pomerania. , 2004, The Angle orthodontist.

[107]  J. Okeson,et al.  The clinical usefulness of surface electromyography in the diagnosis and treatment of temporomandibular disorders. , 2006, Journal of the American Dental Association.

[108]  G. Carlsson,et al.  Treatment Received, Treatment Demand, and Treatment Need for Temporomandibular Disorders in 35-Year-Old Subjects , 2002 .

[109]  D. Vallon,et al.  Occlusal appliance therapy in patients with temporomandibular disorders. A double-blind controlled study in a short-term perspective. , 1998, Acta odontologica Scandinavica.

[110]  D Manfredini,et al.  Temporomandibular disorders assessment: medicolegal considerations in the evidence-based era. , 2011, Journal of oral rehabilitation.

[111]  B. Stegenga,et al.  Temporomandibular joint osteoarthrosis: clinical and radiographic characteristics 30 years after nonsurgical treatment: a preliminary report. , 1993, Cranio : the journal of craniomandibular practice.

[112]  G. Heydecke,et al.  In patients with temporomandibular disorders, do particular interventions influence oral health-related quality of life? A qualitative systematic review of the literature. , 2007, Clinical oral implants research.

[113]  J. Okeson Long-term treatment of disk-interference disorders of the temporomandibular joint with anterior repositioning occlusal splints. , 1988, The Journal of prosthetic dentistry.

[114]  P. Revington,et al.  Arthrocentesis and lavage for treating temporomandibular joint disorders. , 2015, The Cochrane database of systematic reviews.

[115]  J. P. Lund,et al.  Validity of Diagnostic and Monitoring Tests Used for Temporomandibular Disorders , 1995, Journal of dental research.

[116]  C Flores-Mir,et al.  Role of different imaging modalities in assessment of temporomandibular joint erosions and osteophytes: a systematic review. , 2008, Dento maxillo facial radiology.