Aldehyde oxidase and alcohol dehydrogenase genetics in the mouse. New alleles for the Aox-2 and Adh-3 loci.

The genetic variability of one of the liver isozymes of aldehyde oxidase (AOX-B2 or AOX-2) and the stomach isozyme of alcohol dehydrogenase (ADH-C2) has been examined among strains of mice. Evidence is presented for a fourth allele of Aox-2 and a third allele of Adh-3. The hybrid allozyme pattern for mouse liver AOX was consistent with a dimeric subunit structure for this enzyme.