Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis
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Haifeng Zhang | Qihua Zhu | Ming-Fu Cheng | Junjie Wang | Yungen Xu | Yaoyao Wu | Wenjie Wang | Tingting Liang | Weibo Guo | Chunqiu Yu | Jiaming Jin | Yuan Wang | Zhongyan Hao | Teng Jiang | Lifang Cen
[1] Sohita Dhillon. Orelabrutinib: First Approval , 2021, Drugs.
[2] P. Sève,et al. State of the art: approved and emerging JAK inhibitors for rheumatoid arthritis , 2020, Expert opinion on pharmacotherapy.
[3] E. Peeva,et al. Efficacy and Safety of PF‐06651600 (Ritlecitinib), a Novel JAK3/TEC Inhibitor, in Patients With Moderate‐to‐Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate , 2020, Arthritis & rheumatology.
[4] Sohita Dhillon. Tirabrutinib: First Approval , 2020, Drugs.
[5] Yahiya Y. Syed. Zanubrutinib: First Approval , 2020, Drugs.
[6] Michael L. Wang,et al. Durable response with single-agent acalabrutinib in patients with relapsed or refractory mantle cell lymphoma , 2019, Leukemia.
[7] Ling-Jun Ho,et al. Useful message in choosing optimal biological agents for patients with autoimmune arthritis. , 2019, Biochemical pharmacology.
[8] H. Thu,et al. Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: Multi-functionalization as an emerging strategy to optimize therapeutic efficacy. , 2019, Journal of controlled release : official journal of the Controlled Release Society.
[9] R. Everley,et al. PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor. , 2019, ACS chemical biology.
[10] Yifan Feng,et al. Bruton’s tyrosine kinase (BTK) inhibitors in treating cancer: a patent review (2010-2018) , 2019, Expert opinion on therapeutic patents.
[11] Sung,et al. Could Polyphenols Help in the Control of Rheumatoid Arthritis? , 2019, Molecules.
[12] C. Niemann,et al. Targeting Bruton’s Tyrosine Kinase Across B-Cell Malignancies , 2018, Drugs.
[13] J. O’Shea,et al. Translational and clinical advances in JAK‐STAT biology: The present and future of jakinibs , 2018, Journal of leukocyte biology.
[14] Qingsong Liu,et al. Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrimido[5,4- b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors. , 2018, Journal of medicinal chemistry.
[15] J. Kirwan,et al. Is There a Renaissance of Glucocorticoids in Rheumatoid Arthritis? , 2017, Clinical pharmacology and therapeutics.
[16] Xiao-Ming Gao,et al. A study on the risk of fungal infection with tofacitinib (CP-690550), a novel oral agent for rheumatoid arthritis , 2017, Scientific Reports.
[17] G. Firestein,et al. Immunopathogenesis of Rheumatoid Arthritis. , 2017, Immunity.
[18] M. Hegen,et al. Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans. , 2017, Journal of medicinal chemistry.
[19] M. Davids,et al. Inhibition of the Bruton Tyrosine Kinase Pathway in B-Cell Lymphoproliferative Disorders , 2016, Cancer journal.
[20] T. Kipps,et al. Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia. , 2015, The New England journal of medicine.
[21] F. Salituro,et al. Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. , 2015, Journal of medicinal chemistry.
[22] R. Hendriks,et al. BTK Signaling in B Cell Differentiation and Autoimmunity. , 2015, Current topics in microbiology and immunology.
[23] S. Goodman. Rheumatoid arthritis: Perioperative management of biologics and DMARDs. , 2015, Seminars in arthritis and rheumatism.
[24] Mark E Flanagan,et al. Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases. , 2014, Journal of medicinal chemistry.
[25] Leslie J Crofford,et al. Use of NSAIDs in treating patients with arthritis , 2013, Arthritis Research & Therapy.
[26] Steven M Holland,et al. JAKs and STATs in immunity, immunodeficiency, and cancer. , 2013, The New England journal of medicine.
[27] F. Uckun,et al. Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft‐versus‐host disease (GVHD) in a murine allogeneic bone marrow transplantation model , 2004, British journal of haematology.