Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors

Background. Pancreatic cancer has a poor prognosis, and early diagnosis of carcinoma and discrimination between malignant and benign conditions are difficult. Many pancreatic cancer‐associated antigens, such as CA 19‐9, DU‐PAN‐2, YPan‐1, and SPan‐1, have been studied. However, expression of Tn, sialosyl‐Tn, and T antigens in tissues of different types of pancreatic neoplasms has not been investigated systematically. Moreover, little is known about the distribution of different types of apomucins in the pancreas.

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