Yarrowia lipolytica as a potential producer of citric acid from raw glycerol

Aims: To study the biochemical response of Yarrowia lipolytica LGAM S(7)1 during growth on raw glycerol (the main by‐product of bio‐diesel production units) in order to produce metabolic products of industrial significance.

[1]  G. Barth,et al.  Physiology and genetics of the dimorphic fungus Yarrowia lipolytica. , 1997, FEMS microbiology reviews.

[2]  H. Kautola,et al.  Comparison of different strains of the yeastYarrowia lipolytica for citric acid production from glucose hydrol , 1991, Applied biochemistry and biotechnology.

[3]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[4]  K. Rane,et al.  Oxygen uptake and citric acid production by Candida lipolytica Y 1095 , 1994, Biotechnology and bioengineering.

[5]  J. Engasser,et al.  Citric acid production from glucose. II. Growth and excretion kinetics in a trickleflow fermentor , 1979 .

[6]  J. Engasser,et al.  Citric acid production from glucose. I. Growth and excretion kinetics in a stirred fermentor , 1979 .

[7]  C. Ratledge,et al.  Regulatory Studies on Citrate Synthase in Candida 107, an Oleaginous Yeast , 1980 .

[8]  S. Zinjarde,et al.  Dimorphic transition in Yarrowia lipolytica isolated from oil-polluted sea water , 1998 .

[9]  A. Zeng,et al.  Enzymatic evidence for an involvement of pyruvate dehydrogenase in the anaerobic glycerol metabolism of Klebsiella pneumoniae. , 1997, Journal of biotechnology.

[10]  H. Biebl,et al.  Fermentation of glycerol to 1,3-propanediol: use of cosubstrates , 1995, Applied Microbiology and Biotechnology.

[11]  K. Rane,et al.  Citric acid production by Candida lipolytica Y 1095 in cell recycle and fed‐batch fermentors , 1995, Biotechnology and bioengineering.

[12]  T. Roukas,et al.  Pretreatment of date syrup to increase citric acid production , 1997 .

[13]  K. Rane,et al.  Production of citric acid by Candida lipolytica Y1095: Effect of glucose concentration on yield and productivity , 1993 .

[14]  C. Ratledge.  Yeasts, moulds, algae and bacteria as sources of lipids , 1994 .

[15]  D. Cooper,et al.  Self-cycling fermentation of a citric acid producing strain of Candida lipolytica , 1996 .

[16]  S. Papanikolaou,et al.  A mathematical model for the study of lipid accumulation in oleaginous microorganisms. I. Lipid accumulation during growth of Mucor circinelloides CBS 172-27 on a vegetable oil , 1995 .

[17]  D. Kidby,et al.  Lipids of yeasts. , 1975, Bacteriological reviews.

[18]  G. Eggink,et al.  High-cell-density cultivation of the lipid accumulating yeast Cryptococcus curvatus using glycerol as a carbon source , 1996, Applied Microbiology and Biotechnology.

[19]  M. Komaitis,et al.  Enhancement of single cell oil production by Yarrowia lipolytica growing in the presence of Teucrium polium L. aqueous extract , 1999, Biotechnology Letters.

[20]  C. Ratledge,et al.  A biochemical explanation for lipid accumulation in Candida 107 and other oleaginous micro-organisms. , 1979, Journal of general microbiology.

[21]  J. Gaddy,et al.  Continuous fermentation for the production of citric acid from glucose , 1989 .

[22]  Wolf-Dieter Deckwer,et al.  Glycerol conversion to 1,3-propanediol by newly isolated clostridia , 1992, Applied Microbiology and Biotechnology.

[23]  Shuichi Aiba,et al.  Identification of metabolic model: Citrate production from glucose by Candida lipolytica , 1979 .

[24]  A. Radwan,et al.  Production of citric acid from cane molasses on a semi-pilot scale. , 1977 .