Accurate size measurement of needle-shaped particles using digital holography

In this paper, a digital holography based method is proposed to accurately measure the length and orientation of the needle-shaped particles in solution. The method involves recording of the hologram and numerical reconstructions (focusing) of the hologram at several depths. An image analysis routine is then used to determine the length, location and orientation of the particles from the reconstructed images without any a priori information about the orientation of particles. The performance of the method is verified using a single fiber with known size and orientation. Subsequently, the proposed method is applied to a suspension of fibers, where the length measurements are found to be in good agreement with the true values. This proposed technique can overcome the shortcoming of existing 2D imaging tools, which can provide only the projected lengths of randomly oriented particles.

[1]  Gopalkrishna Hegde,et al.  Particle field imaging using digital in-line holography , 2009 .

[2]  Thomas J. Naughton,et al.  Processing of digital holograms for size measurements of microparticlese , 2008, International Symposium on Laser Metrology.

[3]  J. Romagnoli,et al.  Investigation of on-line optical particle characterization in reaction and cooling crystallization systems. Current state of the art , 2002 .

[4]  Zoltan K. Nagy,et al.  Bulk video imaging based multivariate image analysis, process control chart and acoustic signal assisted nucleation detection , 2010 .

[5]  U. Schnars,et al.  Digital Holography: Digital Hologram Recording, Numerical Reconstruction, and Related Techniques , 2004 .

[6]  James B. Rawlings,et al.  An algorithm for analyzing noisy, in situ images of high-aspect-ratio crystals to monitor particle size distribution , 2006 .

[7]  M. Mazzotti,et al.  Modeling and Experimental Analysis of PSD Measurements through FBRM , 2000 .

[8]  R. Braatz,et al.  Measurement of particle size distribution in suspension polymerization using in situ laser backscattering , 2003 .

[9]  Kevin J. Roberts,et al.  Crystal growth measurement using 2D and 3D imaging and the perspectives for shape control , 2008 .

[10]  Mingzhong Li,et al.  Determination of non-spherical particle size distribution from chord length measurements. Part 1: Theoretical analysis , 2005 .

[11]  Thomas J. Naughton,et al.  On-line digital holographic measurement of size and shape of microparticles for crystallization processes , 2008, International Symposium on Laser Metrology.

[12]  Weili Yu,et al.  Chord length characterization using focused beam reflectance measurement probe - methodologies and pitfalls , 2008 .

[13]  M H Jericho,et al.  Digital in-line holography of microspheres. , 2002, Applied optics.

[14]  Kevin J. Roberts,et al.  Integration of crystal morphology modeling and on‐line shape measurement , 2006 .

[15]  D. Lebrun,et al.  Digital In-Line Holography System for 3D-3C Particle Tracking Velocimetry , 2007 .

[16]  James B. Rawlings,et al.  The Potential of Current High-Resolution Imaging-Based Particle Size Distribution Measurements for Crystallization Monitoring , 2009 .

[17]  J. Rawlings,et al.  Industrial crystallization process control , 2006, IEEE Control Systems.

[18]  Debasis Sarkar,et al.  In situ particle size estimation for crystallization processes by multivariate image analysis , 2009 .

[19]  L. L. Simon,et al.  Comparison of external bulk video imaging with focused beam reflectance measurement and ultra-violet visible spectroscopy for metastable zone identification in food and pharmaceutical crystallization processes , 2009 .

[20]  Taslima Khanam,et al.  Three dimensional digital holographic profiling of micro-fibers. , 2009, Optics express.

[21]  Wolfgang Marquardt,et al.  Process Analysis by Means of Focused Beam Reflectance Measurements , 2009 .

[22]  Jianmin Miao,et al.  Dynamic characterization of MEMS diaphragm using time averaged in-line digital holography , 2007 .

[23]  Kumar Patchigolla,et al.  Determination of non-spherical particle size distribution from chord length measurements. Part 2: Experimental validation , 2005 .

[24]  L. Lourenço Particle Image Velocimetry , 1989 .

[25]  W Xu,et al.  Digital in-line holography for biological applications , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Marco Mazzotti,et al.  Measurement of particle size and shape by FBRM and in situ microscopy , 2008 .

[27]  Thomas J. Naughton,et al.  Microparticle characterization using digital holography , 2010 .