Serologic evidence of Encephalitozoon cuniculi infection in a colony of squirrel monkeys (Saimiri sciureus).

Five hundred seventeen serum samples obtained during 3 years from a collection of 250 squirrel monkeys were examined by indirect immunofluorescence and dot-ELISA for antibodies to Encephalitozoon cuniculi. One hundred seventy-nine monkeys were positive at least once and fifty six monkeys were positive three or more times. Older animals were more likely to be positive than young animals, but the proportion of serologically positive monkeys did not change appreciably over the 3 years. As judged by the serological evidence, infection with E. cuniculi is distributed widely in this collection of squirrel monkeys.