Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy.
暂无分享,去创建一个
[1] J. Shuster,et al. Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906 , 2011, Pediatric blood & cancer.
[2] Michael N. Alonso,et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies , 2011, Nature Medicine.
[3] N. Heisterkamp,et al. Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist , 2011, Leukemia.
[4] C. Pui,et al. Biology, risk stratification, and therapy of pediatric acute leukemias: an update. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] L. Ricci-Vitiani,et al. Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells. , 2010, Endocrine-related cancer.
[6] S. Ryu,et al. Targeted label-free quantitative analysis of secretory proteins from adipocytes in response to oxidative stress. , 2010, Analytical biochemistry.
[7] N. Heisterkamp,et al. A functional receptor for B-cell-activating factor is expressed on human acute lymphoblastic leukemias. , 2010, Cancer research.
[8] I. Petit,et al. Can inhibition of the SDF-1/CXCR4 axis eradicate acute leukemia? , 2010, Seminars in cancer biology.
[9] G. Colditz,et al. Obesity and Cancer , 2010, The oncologist.
[10] S. Mittelman,et al. Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice. , 2010, Pharmacological research.
[11] N. Heisterkamp,et al. Development of resistance to dasatinib in Bcr/Abl-positive acute lymphoblastic leukemia , 2010, Leukemia.
[12] C. Dive,et al. Biological mechanisms linking obesity and cancer risk: new perspectives. , 2010, Annual review of medicine.
[13] Z. Estrov,et al. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. , 2009, Blood.
[14] N. Heisterkamp,et al. Adipocytes impair leukemia treatment in mice. , 2009, Cancer research.
[15] F. Visseren,et al. Obesity and Cancer: The Role of Dysfunctional Adipose Tissue , 2009, Cancer Epidemiology, Biomarkers & Prevention.
[16] C. Jung,et al. Association of waist circumference, traditional cardiovascular risk factors, and stromal‐derived factor‐1 in adolescents , 2009, Pediatric diabetes.
[17] M. Lafontan,et al. Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity. , 2009, Biochemical and biophysical research communications.
[18] J. Fenton,et al. Diet‐induced adiposity alters the serum profile of inflammation in C57BL/6N mice as measured by antibody array , 2009, Diabetes, obesity & metabolism.
[19] Shao-fen Lin,et al. Upregulation of stromal cell–derived factor 1 (SDF-1) expression in microvasculature endothelial cells in retinal ischemia-reperfusion injury , 2008, Graefe's Archive for Clinical and Experimental Ophthalmology.
[20] V. Hombach,et al. T-lymphocyte Infiltration in Visceral Adipose Tissue: A Primary Event in Adipose Tissue Inflammation and the Development of Obesity-Mediated Insulin Resistance , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[21] A. Bleyer,et al. Obesity and outcome in pediatric acute lymphoblastic leukemia. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] A. Galinier,et al. Weight-dependent changes of immune system in adipose tissue: importance of leptin. , 2006, Experimental cell research.
[23] C. Massone,et al. Rimming of Adipocytes By Neoplastic Lymphocytes: A Histopathologic Feature Not Restricted to Subcutaneous T-Cell Lymphoma , 2006, The American Journal of dermatopathology.
[24] M. Vignetti,et al. Obesity Independently Predicts Event Free Survival (EFS) in Adults with BCR-ABL-Negative Acute Lymphoblastic Leukemia (ALL). A Retrospective Analysis of Two GIMEMA Studies. , 2005 .
[25] Y. Miyake,et al. CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease , 2005, Clinical and experimental immunology.
[26] G. Botti,et al. Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells , 2005, Cancer Immunology, Immunotherapy.
[27] A. Galinier,et al. Adipose tissues as an ancestral immune organ: Site‐specific change in obesity , 2005, FEBS letters.
[28] A. Bleyer,et al. Obesity and Body Weight Independently Predict Relapse and Survival in Preadolescents and Teenagers with Acute Lymphoblastic Leukemia (ALL). A Retrospective Analysis of Five Children Cancer Group (CCG) Studies. , 2004 .
[29] A. Beaudet,et al. Leukocyte migration in adipose tissue of mice null for ICAM-1 and Mac-1 adhesion receptors. , 2004, Obesity research.
[30] A. Nagler,et al. Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. , 2004, Blood.
[31] L. Tartaglia,et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. , 2003, The Journal of clinical investigation.
[32] Puneeth Iyengar,et al. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization , 2003, Oncogene.
[33] C. Darimont,et al. Reconstitution of telomerase activity combined with HPV-E7 expression allow human preadipocytes to preserve their differentiation capacity after immortalization , 2003, Cell Death and Differentiation.
[34] J. Juarez,et al. Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro , 2003, Leukemia.
[35] Michael J Thun,et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. , 2003, The New England journal of medicine.
[36] Evan T Keller,et al. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. , 2002, Cancer research.
[37] N R Schneider,et al. Precursor B-cell lymphoblastic lymphoma. A study of nine cases lacking blood and bone marrow involvement and review of the literature. , 2001, American journal of clinical pathology.
[38] T. Mcclanahan,et al. Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.
[39] Bernhard Moser,et al. Lymphocyte traffic control by chemokines , 2001, Nature Immunology.
[40] L. Gibson,et al. Stromal cells regulate survival of B-lineage leukemic cells during chemotherapy. , 2000, Blood.
[41] R. Alon,et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. , 2000, Blood.
[42] S. Rafii,et al. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. , 1998, Blood.
[43] M. Baggiolini. Chemokines and leukocyte traffic , 1998, Nature.
[44] F. Behm,et al. Prevalence and growth characteristics of malignant stem cells in B-lineage acute lymphoblastic leukemia. , 1997, Blood.
[45] T. Springer,et al. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) , 1996, The Journal of experimental medicine.
[46] F. Behm,et al. Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells. , 1994, Blood.
[47] G. Buchanan. Diagnosis and management of relapse in acute lymphoblastic leukemia. , 1990, Hematology/oncology clinics of North America.
[48] A. Peled,et al. CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers , 2009, Leukemia.
[49] A. Fielding. The treatment of adults with acute lymphoblastic leukemia. , 2008, Hematology. American Society of Hematology. Education Program.
[50] C. Dive,et al. Obesity and cancer: Pathophysiological and biological mechanisms , 2008, Archives of physiology and biochemistry.
[51] N. Heisterkamp,et al. A farnesyltransferase inhibitor increases survival of mice with very advanced stage acute lymphoblastic leukemia/lymphoma caused by P190 Bcr/Abl , 2004, Leukemia.