Microwave Thermotherapy in Cancer Treatment: Evaluation of Homogeneity of SAR Distribution

Medical applications of microwaves (i.e., a possibility to use microwave energy and/or microwave technique and technology for therapeutical purposes) are a quite new and very rapidly developing fleld. Microwave thermotherapy is being used in medicine for cancer treatment and treatment of some other diseases since early eighties. This paper is a contribution to a theory of phase array applicators to be used for a microwave thermotherapy (microwave hyperthermia) in a cancer treatment. It deals with a study and theoretical evaluation of homogeneity of SAR distribution in cylindrical agar phantom for several difierent values of its radius. Discussed SAR distribution is in our case created by simulations of EM fleld exposure done by aid of four microwave stripline type TEM mode applicators of the same type.

[1]  Swagatam Das,et al.  A MODIFIED DIFFERENTIAL EVOLUTION ALGORITHM FOR SHAPED BEAM LINEAR ARRAY ANTENNA DESIGN , 2012 .

[2]  A. Bel,et al.  The impact of the waveguide aperture size of the 3D 70 MHz AMC-8 locoregional hyperthermia system on tumour coverage , 2010, Physics in medicine and biology.

[3]  Rick Siow Mong Goh,et al.  Implementation of the FDTD Method Based on Lorentz-Drude Dispersive Model on GPU for Plasmonics Applications , 2011 .

[4]  Wen-Yan Yin,et al.  A Novel Dielectric Conformal FDTD Method for Computing SAR Distribution of the Human Body in a Metallic Cabin Illuminated by an Intentional Electromagnetic Pulse (Iemp) , 2012 .

[5]  J. Soler,et al.  Human Body Effects on Implantable Antennas for ISM Bands Applications : Models Comparison and Propagation Losses Study , 2010 .

[6]  USING NANOPARTICLES FOR ENHANCING THE FOCUSING HEATING EFFECT OF AN EXTERNAL WAVEGUIDE APPLICATOR FOR ONCOLOGY HYPER- THERMIA: EVALUATION IN MUSCLE AND TUMOR PHANTOMS , 2011 .

[7]  Edward Jones,et al.  Investigation of Classifiers for Early-Stage Breast Cancer Based on Radar Target Signatures , 2010 .

[8]  Muhammad Ramlee Kamarudin,et al.  Electronically switched beam disk-loaded monopole array antenna , 2010 .

[9]  Gideon Kantor,et al.  A comparative heating‐pattern study of direct‐contact applicators in microwave diathermy , 1977 .

[10]  Stuart Harmer,et al.  ON BODY CONCEALED WEAPON DETECTION USING A PHASED ANTENNA ARRAY , 2012 .

[11]  Ibrahim Elshafiey,et al.  A New Low SAR Antenna Structure for Wireless Handset Applications , 2011 .

[12]  Sotirios K. Goudos,et al.  Application of Taguchi's Optimization Method and Self-Adaptive Differential Evolution to the Synthesis of Linear Antenna Arrays , 2010 .

[13]  Edward Jones,et al.  CHANNEL-RANKED BEAMFORMER FOR THE EARLY DETECTION OF BREAST CANCER , 2010 .

[14]  William W Mayo-Smith,et al.  Microwave ablation: principles and applications. , 2005, Radiographics : a review publication of the Radiological Society of North America, Inc.

[15]  R. Issels,et al.  Hyperthermia in oncology. , 2001, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[16]  H. Majid,et al.  Log periodic fractal koch antenna for UHF band applications , 2010 .

[17]  A. Taflove,et al.  Finite-difference time-domain analysis of a complete transverse electromagnetic cell loaded with liquid biological media in culture dishes , 1998, IEEE Transactions on Biomedical Engineering.

[18]  T. Wilt,et al.  Microwave thermotherapy for benign prostatic hyperplasia. , 2012, The Cochrane database of systematic reviews.

[19]  P. Wust,et al.  Hyperthermia in combined treatment of cancer. , 2002, The Lancet Oncology.

[20]  C. Trujillo-Romero,et al.  FEM Modeling for Performance Evaluation of an Electromagnetic Oncology Deep Hyperthermia Applicator When Using Monopole, Inverted T, and Plate Antennas , 2011 .

[21]  Jan Vrba.  Medical Applications of Microwaves , 2005 .

[22]  Farooq A. Tahir,et al.  Equivalent Electrical Circuit for Designing MEMS-Controlled Reflectarray Phase Shifters , 2010 .

[23]  Feng Yang,et al.  DOA Estimation with Sub-Array Divided Technique and Interporlated ESPRIT Algorithm on a Cylindrical Conformal Array Antenna , 2010 .

[24]  Margarethus M. Paulides,et al.  A head and neck hyperthermia applicator: Theoretical antenna array design , 2007, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[25]  E. Gelvich,et al.  An attempt at quantitative specification of SAR distribution homogeneity. , 1996, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[26]  Guy A. E. Vandenbosch,et al.  Novel Low-Cost End-Wall Microstrip-to-Waveguide Splitter Transition , 2010 .

[27]  Peter Wust,et al.  Simulation of different applicator positions for treatment of a presacral tumour , 2007, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[28]  Changhua Chen,et al.  DESIGN AND EXPERIMENTS OF THE GW HIGH- POWER MICROWAVE FEED HORN , 2010 .

[29]  Myron L. Crawford,et al.  Generation of Standard EM Fields Using TEM Transmission Cells , 1974 .

[30]  S. Curto,et al.  DETUNING STUDY OF IMPLANTABLE ANTENNAS INSIDE THE HUMAN BODY , 2012 .

[31]  Bing-Zhong Wang,et al.  APPLICATION OF THE IMPROVED MATRIX TYPE FDTD METHOD FOR ACTIVE ANTENNA ANALYSIS , 2010 .

[32]  Theodoros Samaras,et al.  Reevaluation and improved design of the TEM cell in vitro exposure unit for replication studies , 2005, Bioelectromagnetics.

[33]  K. Low,et al.  Homogeneous and Heterogeneous Breast Phantoms for Ultra-Wideband Microwave Imaging Applications , 2010 .

[34]  Lorenzo Crocco,et al.  Optimal Constrained Field Focusing for Hyperthermia Cancer Therapy: a Feasibility Assessment on Realistic Phantoms , 2010 .

[35]  Edward Jones,et al.  ROTATING ANTENNA MICROWAVE IMAGING SYSTEM FOR BREAST CANCER DETECTION , 2010 .

[36]  Lixin Guo,et al.  FDTD Method Investigation on the Polarimetric Scattering from 2-D Rough Surface , 2010 .