Injury and Repair: Prostheses

Sight restoration in the event of retinal degenerative diseases or even loss of the eyes has been an aim of researchers for over 50 years. Cortical prostheses, where visual signals are transmitted directly from a camera to the visual cortex, were the first to be studied, although technical difficulties and tissue complexities have slowed progress in this area. Research on retinal electronic prosthetic devices has been more successful, with many groups around the world working on a technology that effectively replaces retinal photoreceptor cells. Proof of principle has been established in that initial results from prosthesis clinical trials have demonstrated restoration of light perception and some form of vision in subjects originally having no or bare light perception.

[1]  Daniel Palanker,et al.  Design of a high-resolution optoelectronic retinal prosthesis , 2005, Journal of neural engineering.

[2]  E. Zrenner.  Will Retinal Implants Restore Vision ? , 2002 .

[3]  Wentai Liu,et al.  Retinal Prosthesis , 2018, Essentials in Ophthalmology.

[4]  Mark S Humayun,et al.  Predicting visual sensitivity in retinal prosthesis patients. , 2009, Investigative ophthalmology & visual science.

[5]  G. Brindley,et al.  The sensations produced by electrical stimulation of the visual cortex , 1968, The Journal of physiology.

[6]  R Clay Reid,et al.  Demonstration of artificial visual percepts generated through thalamic microstimulation , 2007, Proceedings of the National Academy of Sciences.

[7]  J. Weiland,et al.  Retinal prostheses for the blind. , 2006, Annals of the Academy of Medicine, Singapore.

[8]  J. Rizzo,et al.  Outer retinal degeneration: an electronic retinal prosthesis as a treatment strategy. , 2004, Archives of ophthalmology.

[9]  Avi Caspi,et al.  Feasibility study of a retinal prosthesis: spatial vision with a 16-electrode implant. , 2009, Archives of ophthalmology.

[10]  J. Weiland,et al.  Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosa. , 2007, American journal of ophthalmology.

[11]  D. J. Warren,et al.  A neural interface for a cortical vision prosthesis , 1999, Vision Research.

[12]  Gislin Dagnelie,et al.  Psychophysical evaluation for visual prosthesis. , 2008, Annual review of biomedical engineering.