Inducers of cytochrome P-450d: influence on microsomal catalytic activities and differential regulation by enzyme stabilization.

[1]  S. Aust,et al.  Specific binding of polyhalogenated aromatic hydrocarbon inducers of cytochrome P-450d to the cytochrome and inhibition of its estradiol 2-hydroxylase activity. , 1987, Toxicology and applied pharmacology.

[2]  G. Farrell,et al.  Selective reactivation of steroid hydroxylases following dissociation of the isosafrole metabolite complex with rat hepatic cytochrome P-450. , 1986, Archives of biochemistry and biophysics.

[3]  P. Watkins,et al.  Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. , 1986, The Journal of biological chemistry.

[4]  M. Redinbaugh,et al.  Adaptation of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions. , 1986, Analytical biochemistry.

[5]  R. Tukey,et al.  Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6. , 1985, DNA.

[6]  R. Mayer,et al.  Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. , 1985, Biochemical pharmacology.

[7]  S. Wrighton,et al.  Synthesis and degradation of 3-methylcholanthrene-inducible cytochromes P-450 and their mRNAs in primary monolayer cultures of adult rat hepatocytes. , 1985, Archives of biochemistry and biophysics.

[8]  D. Nebert,et al.  Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence. , 1985, Science.

[9]  J. Whitlock,et al.  Control of cytochrome P1-450 gene expression by dioxin. , 1985, Science.

[10]  P. Thomas,et al.  Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species. , 1984, Archives of biochemistry and biophysics.

[11]  F. Guengerich,et al.  Turnover of membrane proteins: kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolase. , 1984, Archives of biochemistry and biophysics.

[12]  T. Gasiewicz,et al.  Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Evidence for a homologous nature among various mammalian species. , 1984, Molecular pharmacology.

[13]  R. Tukey,et al.  Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthrene. , 1984, Molecular pharmacology.

[14]  L. Shawver,et al.  An enzyme-linked immunoadsorbent assay for measuring cytochrome b5 and NADPH-cytochrome P-450 reductase in rat liver microsomal fractions. Evidence for functionally inactive protein. , 1984, The Biochemical journal.

[15]  P. Thomas,et al.  Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics. , 1983, The Journal of biological chemistry.

[16]  F. Guengerich,et al.  Regulation of cytochrome P-450. Immunochemical quantitation of eight isozymes in liver microsomes of rats treated with polybrominated biphenyl congeners. , 1983, The Journal of biological chemistry.

[17]  F. Guengerich,et al.  Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone. , 1982, Biochemistry.

[18]  P. Thomas,et al.  Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls☆ , 1982 .

[19]  J. Fouts,et al.  A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. , 1980, Analytical biochemistry.

[20]  P. Thomas,et al.  Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms. , 1980, The Journal of biological chemistry.

[21]  T. Nambara,et al.  A simple radiometric assay for estradiol 2-hydroxylase activity. , 1980, Analytical Biochemistry.

[22]  N. Ozawa,et al.  3,4,5,3',4'-Pentachlorobiphenyl as a useful inducer for purification of rat liver microsomal cytochrome P448. , 1979, Biochemical and biophysical research communications.

[23]  J. Bridges,et al.  Interaction of isosafrole in vivo with rat hepatic microsomal cytochrome P-450 following treatment with phenobarbitone or 20-methylcholanthrene. , 1979, Biochemical pharmacology.

[24]  J. Q. Rose,et al.  The fate of 2,3,7,8-tetrachlorodibenzo-p-dioxin following single and repeated oral doses to the rat. , 1976, Toxicology and applied pharmacology.

[25]  R. Schimke,et al.  Studies on the synthesis and degradation of proteins of the endoplasmic reticulum of rat liver. , 1969, The Journal of biological chemistry.

[26]  R. Schimke,et al.  THE IMPORTANCE OF BOTH SYNTHESIS AND DEGRADATION IN THE CONTROL OF ARGINASE LEVELS IN RAT LIVER. , 1964, The Journal of biological chemistry.

[27]  T. Omura,et al.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE. , 1964, The Journal of biological chemistry.

[28]  H. Yoshimura,et al.  High affinity of 2,3,4,7,8-pentachlorodibenzofuran to cytochrome P-450 in the hepatic microsomes of rats , 1986 .

[29]  D. Waxman,et al.  17 beta-estradiol 2- and 4-hydroxylation catalyzed by rat hepatic cytochrome P-450: roles of individual forms, inductive effects, developmental patterns, and alterations by gonadectomy and hormone replacement. , 1986, Endocrinology.

[30]  D. Nebert,et al.  Cytochrome P450 gene expression and regulation , 1985 .

[31]  E. Hodgson,et al.  The induction of cytochrome P-450 by isosafrole and related methylenedioxyphenyl compounds. , 1985, Chemico-biological interactions.

[32]  J. Depierre,et al.  Metabolism of 2-acetylaminofluorene by eight different forms of cytochrome P-450 isolated from rat liver. , 1985, Carcinogenesis.

[33]  Y. Imai.  Interaction of polycyclic hydrocarbons with cytochrome P-450. I. Specific binding of various hydrocarbons to P-448(1). , 1982, Journal of biochemistry.

[34]  J. Bridges,et al.  Further studies on the dissociation of the isosafrole metabolite-cytochrome P-450 complex. , 1979, Biochemical pharmacology.

[35]  R. Schimke,et al.  THE ROLES OF SYNTHESIS AND DEGRADATION IN THE CONTROL OF RAT LIVER TRYPTOPHAN PYRROLASE. , 1965, The Journal of biological chemistry.