Toward an efficient brain tumor extraction using level set method and pennes bioheat equation

The aim of this paper is to present a new approach for improving deformable models and especially the Level Set Method (LSM) for segmentation and extraction of brain tumors in MRI (Magnetic Resonance Imaging) with more accuracy, the contribution of this work is to exploit thermal behavior of brain tumors for correcting level set contours. Human Body temperature distribution is an indicator of health condition, the brain tumor cells generate more heat than normal brain cells due to their higher metabolism and their vascular dilation. Heat distribution in human body is modeled using Pennes BioHeat Transfer Equation (PBHTE) solved by Finite Volume Method (FVM), and with the inverse analysis using Genetic Algorithm (GA) we will estimate the size and location of brain tumor, with this way Level Set Method extracts tumors contours with more accuracy and efficiency. To our knowledge, this is the first approach which introduces thermal analysis to improve the accuracy of segmentation and extraction of tumors in MRI images.

[1]  Xun Wang,et al.  A comparative study of deformable contour methods on medical image segmentation , 2008, Image Vis. Comput..

[2]  Frank Lindseth,et al.  Medical image segmentation on GPUs - A comprehensive review , 2015, Medical Image Anal..

[3]  Jing Liu,et al.  An efficient parallel numerical modeling of bioheat transfer in realistic tissue structure , 2016 .

[4]  Koushik Das,et al.  Numerical analysis for determination of the presence of a tumor and estimation of its size and location in a tissue. , 2013, Journal of thermal biology.

[5]  J. Sethian,et al.  Fronts propagating with curvature-dependent speed: algorithms based on Hamilton-Jacobi formulations , 1988 .

[6]  Laurent D. Cohen,et al.  On active contour models and balloons , 1991, CVGIP Image Underst..

[7]  Astrid Wang,et al.  Snakes Active contours models for boundary detection , 2003 .

[8]  R. Leahy,et al.  Magnetic Resonance Image Tissue Classification Using a Partial Volume Model , 2001, NeuroImage.

[9]  Jean-Louis Dillenseger,et al.  Fast FFT-based bioheat transfer equation computation , 2010, Comput. Biol. Medicine.

[10]  Demetri Terzopoulos,et al.  Deformable models in medical image analysis: a survey , 1996, Medical Image Anal..

[11]  C. K. Charny,et al.  Mathematical Models of Bioheat Transfer , 1992 .

[12]  Subhash C. Mishra,et al.  Non-invasive estimation of size and location of a tumor in a human breast using a curve fitting technique ☆ , 2014 .

[13]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[14]  Baba C. Vemuri,et al.  Shape Modeling with Front Propagation: A Level Set Approach , 1995, IEEE Trans. Pattern Anal. Mach. Intell..

[15]  Julio C. Rolon,et al.  Medical image segmentation with deformable models on graphics processing units , 2013, The Journal of Supercomputing.

[16]  D CohenLaurent On active contour models and balloons , 1991 .

[17]  Jerry L. Prince,et al.  Gradient vector flow: a new external force for snakes , 1997, Proceedings of IEEE Computer Society Conference on Computer Vision and Pattern Recognition.

[18]  H. H. Penns Analysis of tissue and arterial blood temperatures in the resting human forearm , 1948 .

[19]  V. Umadevi,et al.  Framework for estimating tumour parameters using thermal imaging , 2011, The Indian journal of medical research.

[20]  J. P. Agnelli,et al.  Tumor location and parameter estimation by thermography , 2011, Math. Comput. Model..