Biosensing Applications of Molecularly Imprinted Nanomaterials

Chemical sensors and biosensors have attracted considerable attention within the field of modern analytical chemistry, as seen both from the number of publications and from the diversity of approaches and techniques. This is essentially due to new demands and opportunities that are appearing particularly in clinical settings, (e.g., routine blood testing), environmental monitoring, warfare protection, homeland security, food analysis, illicit drug detection, and genotoxicity. Sensor development has been driven, in large part, by the need for new devices that are less expensive and simpler to construct and operate, that provide adequate detection limits and selectivity, and that are accurate and reliable.

[1]  Nicholas W Turner,et al.  Formation of protein molecular imprints within Langmuir monolayers: a quartz crystal microbalance study. , 2007, Journal of colloid and interface science.

[2]  I. Nicholls,et al.  Recognition and enantioselection of drugs and biochemicals using molecularly imprinted polymer technology. , 1995, Trends in biotechnology.

[3]  Priyabrata Pattnaik,et al.  Surface plasmon resonance , 2005, Applied biochemistry and biotechnology.

[4]  F. Arnold,et al.  A glucose-sensing polymer , 1997, Nature Biotechnology.

[5]  M. Lapkowski,et al.  Application of the electronic conducting polymers as sensors: Polyaniline in the solid state for detection of solvent vapours and polypyrrole for detection of biological ions in solutions , 1989 .

[6]  Hardy S. O. Chan,et al.  Enantioselective molecular imprinting polymer coated QCM for the recognition of l-tryptophan , 2006 .

[7]  Yanxiu Zhou,et al.  Potentiometric Sensing of Chiral Amino Acids , 2003 .

[8]  Daming Gao,et al.  Molecular imprinting at walls of silica nanotubes for TNT recognition. , 2008, Analytical chemistry.

[9]  D. Huryn,et al.  Screening of 5-HT1A receptor antagonists using molecularly imprinted polymers. , 2007, Journal of the American Chemical Society.

[10]  Z. Zhang,et al.  Molecularly imprinted polymer-based chemiluminescence array sensor for the detection of proline. , 2010, Analytica chimica acta.

[11]  Toshifumi Takeuchi,et al.  Combinatorial Molecular Imprinting: An Approach to Synthetic Polymer Receptors , 1999 .

[12]  Y. Muramatsu,et al.  Potentiometric immunosensor using artificial antibody based on molecularly imprinted polymers. , 2004, Analytical chemistry.

[13]  Tzong-Zeng Wu,et al.  Recognition of dengue virus protein using epitope-mediated molecularly imprinted film. , 2005, Analytical chemistry.

[14]  Lei Ye,et al.  Molecular imprinting: Synthetic materials as substitutes for biological antibodies and receptors , 2008 .

[15]  Klaus Mosbach,et al.  Drug assay using antibody mimics made by molecular imprinting , 1993, Nature.

[16]  S. Rimmer,et al.  Surface Molecularly Imprinted Polymer Core–Shell Particles , 2004 .

[17]  H. Ju,et al.  A Molecularly Imprinted Copolymer Designed for Enantioselective Recognition of Glutamic Acid , 2007 .

[18]  F. H. Dickey,et al.  The Preparation of Specific Adsorbents. , 1949, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Toshifumi Takeuchi,et al.  Fluorescent imprinted polymers prepared with 2-acrylamidoquinoline as a signaling monomer. , 2005, Organic letters.

[20]  C. Alexander,et al.  Enhancement of selectivity of imprinted polymers via post-imprinting modification of recognition sites , 2000 .

[21]  Naoki Takahara,et al.  Fabrication of glucose-sensitive TiO2 ultrathin films by molecular imprinting and selective detection of monosaccharides , 2008 .

[22]  Klaus Mosbach,et al.  Studies on guest selective molecular recognition on an octadecyl silylated silicon surface using ellipsometry , 1988 .

[23]  D. Spivak Optimization, evaluation, and characterization of molecularly imprinted polymers. , 2005, Advanced drug delivery reviews.

[24]  Takaomi Kobayashi,et al.  Molecular imprinting of caffeine and its recognition assay by quartz-crystal microbalance , 2001 .

[25]  F. Dickert,et al.  Synthetic receptors as sensor coatings for molecules and living cells. , 2001, The Analyst.

[26]  John D. Brennan,et al.  Properties and applications of proteins encapsulated within sol–gel derived materials , 2002 .

[27]  D. Tai,et al.  Epitope-cavities generated by molecularly imprinted films measure the coincident response to anthrax protective antigen and its segments. , 2010, Analytical chemistry.

[28]  Barbara Wandelt,et al.  Fluorescent Functional Recognition Sites through Molecular Imprinting. A Polymer-Based Fluorescent Chemosensor for Aqueous cAMP. , 1998 .

[29]  Mercedes Crego-Calama,et al.  Design of fluorescent materials for chemical sensing. , 2007, Chemical Society reviews.

[30]  Bruce Dunn,et al.  Sol-gel encapsulation methods for biosensors , 1994 .

[31]  Klaus Mosbach,et al.  Competitive amperometric morphine sensor based on an agarose immobilised molecularly imprinted polymer , 1995 .

[32]  K. Mosbach,et al.  A Biomimetic Sensor Based on a Molecularly Imprinted Polymer as a Recognition Element Combined with Fiber-Optic Detection , 1995 .

[33]  Franz L. Dickert,et al.  Mass-sensitive detection of cells, viruses and enzymes with artificial receptors , 2003 .

[34]  Virapong Prachayasittikul,et al.  Molecularly imprinted polymer thin films on quartz crystal microbalance using a surface bound photo-radical initiator , 2005 .

[35]  Jianping Li,et al.  A sensitive and selective sensor for dopamine determination based on a molecularly imprinted electropolymer of o-aminophenol , 2009 .

[36]  Huangxian Ju,et al.  Surface molecularly imprinted nanowire for protein specific recognition. , 2008, Chemical communications.

[37]  Xianwen Kan,et al.  Composites of Multiwalled Carbon Nanotubes and Molecularly Imprinted Polymers for Dopamine Recognition , 2008 .

[38]  M. Whitcombe,et al.  Chapter 7 – Covalent imprinting using sacrificial spacers , 2001 .

[39]  A. Dzgoev,et al.  ENANTIOSELECTIVE MOLECULARLY IMPRINTED POLYMER MEMBRANES , 1999 .

[40]  Yong Li,et al.  Protein recognition via surface molecularly imprinted polymer nanowires. , 2006, Analytical chemistry.

[41]  Klaus Mosbach,et al.  Highly enantioselective and substrate-selective polymers obtained by molecular imprinting utilizing noncovalent interactions. NMR and chromatographic studies on the nature of recognition , 1988 .

[42]  Wlodzimierz Kutner,et al.  Selective histamine piezoelectric chemosensor using a recognition film of the molecularly imprinted polymer of bis(bithiophene) derivatives. , 2009, Analytical chemistry.

[43]  A. Rachkov,et al.  Preparation of azobenzene-containing polymer membranes that function in photoregulated molecular recognition , 2004 .

[44]  Bing Han,et al.  Surface-imprinted core-shell nanoparticles for sorbent assays. , 2007, Analytical chemistry.

[45]  Victoria A. VanderNoot,et al.  Surface plasmon resonance sensors using molecularly imprinted polymers for sorbent assay of theophylline, caffeine, and xanthine , 1998 .

[46]  Jianrong Chen,et al.  Nanotechnology and biosensors. , 2004, Biotechnology advances.

[47]  E. V. Piletskaya,et al.  Molecularly imprinted self-assembled films with specificity to cholesterol , 1999 .

[48]  M. E. Díaz-García,et al.  Molecularly Imprinted Polymers and Optical Sensing Applications , 2000 .

[49]  Evgeny N Vulfson,et al.  Template-Mediated Synthesis of a Polymeric Receptor Specific to Amino Acid Sequences. , 1999, Angewandte Chemie.

[50]  Chad A Mirkin,et al.  Rationally designed nanostructures for surface-enhanced Raman spectroscopy. , 2008, Chemical Society reviews.

[51]  B. Sellergren,et al.  Molecularly imprinted composite materials via iniferter-modified supports , 2002 .

[52]  Börje Sellergren,et al.  A stoichiometric molecularly imprinted polymer for the class-selective recognition of antibiotics in aqueous media. , 2006, Angewandte Chemie.

[53]  Yamada,et al.  Chemiluminescent reaction of fluorescent organic compounds with KHSO5 using cobalt(II) as catalyst and its first application to molecular imprinting , 2000, Analytical chemistry.

[54]  Amy L. Graham,et al.  Development and characterization of molecularly imprinted sol-gel materials for the selective detection of DDT. , 2002, Analytical chemistry.

[55]  Lihua Shen,et al.  Flow injection chemiluminescence determination of epinephrine using epinephrine-imprinted polymer as recognition material , 2003 .

[56]  Youwen Tang,et al.  An Electrochemical Sensor for Phenylephrine Based on Molecular Imprinting , 2009, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[57]  K. Shea,et al.  Imprinted Polymer Membranes for the Selective Transport of Targeted Neutral Molecules , 1996 .

[58]  M. Newton,et al.  Drosophila RNAi screen identifies host genes important for influenza virus replication , 2008, Nature.

[59]  Mark E. Davis,et al.  Molecular imprinting of bulk, microporous silica , 2000, Nature.

[60]  Huang-Hao Yang,et al.  Surface molecularly imprinted nanowires for biorecognition. , 2005, Journal of the American Chemical Society.

[61]  Bin Yu,et al.  Potentiometric sensor for dipicolinic acid. , 2005, Biosensors & bioelectronics.

[62]  L. Meng,et al.  Dye‐molecular‐imprinted polysiloxanes. II. Preparation, characterization, and recognition behavior , 2004 .

[63]  Y. Huang,et al.  Surface Plasmon Resonance Studies on Molecular Imprinting , 2002 .

[64]  Xiao Li,et al.  Adsorption of dansylated amino acids on molecularly imprinted surfaces: a surface plasmon resonance study. , 2006, Biosensors & bioelectronics.

[65]  Zhenyang Wang,et al.  Imprinting of Molecular Recognition Sites on Nanostructures and Its Applications in Chemosensors , 2008, Sensors.

[66]  Maria-Magdalena Titirici,et al.  Thin Molecularly Imprinted Polymer Films via Reversible Addition−Fragmentation Chain Transfer Polymerization , 2006 .

[67]  Chin I Lin,et al.  Synthesis and photoluminescence study of molecularly imprinted polymers appended onto CdSe/ZnS core-shells. , 2004, Biosensors & bioelectronics.

[68]  David R Walt,et al.  Optical imaging fiber-based single live cell arrays: a high-density cell assay platform. , 2002, Analytical chemistry.

[69]  H. Tao,et al.  pH-responsive molecularly imprinted polymers. , 2003, Angewandte Chemie.

[70]  A. El'skaya,et al.  Sensors for low-weight organic molecules based on molecular imprinting technique , 1994 .

[71]  Isao Karube,et al.  Atrazine sensing by molecularly imprinted membranes , 1995 .

[72]  Itamar Willner,et al.  Surface plasmon resonance analysis of antibiotics using imprinted boronic acid-functionalized Au nanoparticle composites. , 2010, Analytical chemistry.

[73]  Daming Gao,et al.  A surface functional monomer-directing strategy for highly dense imprinting of TNT at surface of silica nanoparticles. , 2007, Journal of the American Chemical Society.

[74]  Daoben Zhu,et al.  Fluorescent Conjugated Polyelectrolytes for Biomacromolecule Detection , 2008 .

[75]  O. Wolfbeis,et al.  A spreader-bar approach to molecular architecture: formation of stable artificial chemoreceptors. , 1999, Angewandte Chemie.

[76]  P. Kofinas,et al.  Molecular imprinting of peptides and proteins in aqueous media , 2007, Analytical and bioanalytical chemistry.

[77]  Zhongping Zhang,et al.  Surface molecular self-assembly for organophosphate pesticide imprinting in electropolymerized poly(p-aminothiophenol) membranes on a gold nanoparticle modified glassy carbon electrode. , 2010, Analytical chemistry.

[78]  I. Willner,et al.  Tailored chemosensors for chloroaromatic acids using molecular imprinted TiO2 thin films on ion-sensitive field-effect transistors. , 2001, Analytical chemistry.

[79]  Sergey A. Piletsky,et al.  Electrochemical Sensors Based on Molecularly Imprinted Polymers , 2002 .

[80]  B. Sellergren Imprinted dispersion polymers: A new class of easily accessible affinity stationary phases , 1994 .

[81]  Colette McDonagh,et al.  Optical chemical sensors. , 2008, Chemical reviews.

[82]  Jonathan S. Dordick,et al.  Catalytic Silica Particles via Template-Directed Molecular Imprinting , 2000 .

[83]  Zhongpin Zhang,et al.  Single‐Hole Hollow Polymer Microspheres toward Specific High‐Capacity Uptake of Target Species , 2007 .

[84]  A. Turner,et al.  Molecularly imprinted polymers for the recognition of proteins: the state of the art. , 2007, Biosensors & bioelectronics.

[85]  S. Trolier-McKinstry,et al.  Thin Film Piezoelectrics for MEMS , 2004 .

[86]  M. Mizuhata,et al.  Protein-templated organic/inorganic hybrid materials prepared by liquid-phase deposition. , 2007, Journal of the American Chemical Society.

[87]  Isao Karube,et al.  Imprinted membranes for sensor technology : Opposite behavior of covalently and noncovalently imprinted membranes , 1998 .

[88]  M. Moreno-Bondi,et al.  Frontiers in chemical sensors : Novel principles and techniques , 2005 .

[89]  Yen Wah Tong,et al.  Molecularly imprinted beads by surface imprinting , 2007, Analytical and bioanalytical chemistry.

[90]  Buddy D. Ratner,et al.  Template-imprinted nanostructured surfaces for protein recognition , 1999, Nature.

[91]  Adil Denizli,et al.  Molecularly imprinted ligand-exchange recognition assay of glucose by quartz crystal microbalance. , 2005, Biosensors & bioelectronics.

[92]  Deyong He,et al.  Micro flow sensor on a chip for the determination of terbutaline in human serum based on chemiluminescence and a molecularly imprinted polymer. , 2006, Talanta.

[93]  K. Shimizu,et al.  Colorimetric and fluorometric molecularly imprinted polymer sensors and binding assays , 2007 .

[94]  Frank V Bright,et al.  Molecularly imprinted xerogels as platforms for sensing. , 2007, Accounts of chemical research.

[95]  H. Ju,et al.  Artificial receptor-functionalized nanoshell: facile preparation, fast separation and specific protein recognition , 2010, Nanotechnology.

[96]  K Mosbach,et al.  Imprinted polymer-based sensor system for herbicides using differential-pulse voltammetry on screen-printed electrodes. , 1999, Analytical chemistry.

[97]  N K Chaudhury,et al.  Entrapment of biomolecules in sol-gel matrix for applications in biosensors: problems and future prospects. , 2007, Biosensors & bioelectronics.

[98]  S. Tokonami,et al.  Review: micro- and nanosized molecularly imprinted polymers for high-throughput analytical applications. , 2009, Analytica chimica acta.

[99]  K. Mosbach,et al.  Study of the nature of recognition in molecularly imprinted polymers , 1996 .

[100]  W. Kutner,et al.  Imprinted polymer-based enantioselective acoustic sensor using a quartz crystal microbalance , 1999 .

[101]  Y. Ge,et al.  Selectivity of response in fluorescent polymers imprinted with N1-benzylidene pyridine-2-carboxamidrazones , 2001 .

[102]  K. Mosbach,et al.  A Simple Method for Spin‐Coating Molecularly Imprinted Polymer Films of Controlled Thickness and Porosity , 2004 .

[103]  Bruce Dunn,et al.  Synthesis of sol-gel encapsulated heme proteins with chemical sensing properties , 1999 .

[104]  B. Dave,et al.  Selective Intake and Release of Proteins by Organically-Modified Silica Sol−Gels , 1998 .

[105]  G. Robertson,et al.  Evaluation of the recognition ability of molecularly imprinted materials by surface plasmon resonance (SPR) spectroscopy , 2003 .

[106]  Jong-Man Kim,et al.  Fluorogenic polydiacetylene supramolecules: immobilization, micropatterning, and application to label-free chemosensors. , 2008, Accounts of chemical research.

[107]  Yanxiu Zhou,et al.  Potentiometric sensing of chemical warfare agents: surface imprinted polymer integrated with an indium tin oxide electrode. , 2004, Analytical chemistry.

[108]  K. Mosbach,et al.  The Use of Immobilized Templates-A New Approach in Molecular Imprinting. , 2000, Angewandte Chemie.

[109]  R. Bilewicz,et al.  Measurement of Ibuprofen Binding to Mixed Monolayers Containing β-Cyclodextrin Active Sites , 2004 .

[110]  C. R. Martin,et al.  Selectively-Permeable Ultrathin Film Composite Membranes Based on Molecularly-Imprinted Polymers , 1998 .

[111]  K. Shea,et al.  Synthetic peptide receptors: molecularly imprinted polymers for the recognition of peptides using peptide-metal interactions. , 2001, Journal of the American Chemical Society.

[112]  W. Buma,et al.  Fluorescent, molecularly imprinted thin‐layer films based on a common polymer , 2007 .

[113]  A. Turner,et al.  Surface-grafted molecularly imprinted polymers for protein recognition. , 2001, Analytical chemistry.

[114]  B. Eggins Chemical Sensors and Biosensors , 2002 .

[115]  Franz L Dickert,et al.  Biomimetic ABO blood-group typing. , 2006, Angewandte Chemie.

[116]  Franz L. Dickert,et al.  Selective Microorganism Detection with Cell Surface Imprinted Polymers , 2001 .

[117]  Michael J. Whitcombe,et al.  A NEW METHOD FOR THE INTRODUCTION OF RECOGNITION SITE FUNCTIONALITY INTO POLYMERS PREPARED BY MOLECULAR IMPRINTING : SYNTHESIS AND CHARACTERIZATION OF POLYMERIC RECEPTORS FOR CHOLESTEROL , 1995 .

[118]  Daming Gao,et al.  Surface molecular self-assembly strategy for TNT imprinting of polymer nanowire/nanotube arrays. , 2006, Analytical chemistry.

[119]  C. Allender,et al.  Molecular imprinted polymer sensors: implications for therapeutics. , 2005, Advanced drug delivery reviews.

[120]  Jitao Huang,et al.  Template imprinting amphoteric polymer for the recognition of proteins , 2005 .

[121]  Guo-Li Shen,et al.  Enantioselective Recognition of Amino Acid by Differential Pulse Voltammetry in Molecularly Imprinted Monolayers Assembled on Au Electrodes , 2004 .

[122]  Imprinting as a versatile platform for sensitive materials – nanopatterning of the polymer bulk and surfaces , 2005 .

[123]  Jürgen Hürttlen,et al.  Gas phase detection of explosives such as 2,4,6-trinitrotoluene by molecularly imprinted polymers. , 2007, Analytica chimica acta.

[124]  Xiaoling Wei,et al.  Surface molecular imprinting by atom transfer radical polymerization. , 2005, Biomacromolecules.

[125]  F. Dickert,et al.  Bioimprinting of polymers and sol-gel phases. Selective detection of yeasts with imprinted polymers. , 2002, Analytical chemistry.

[126]  Katsuya Kato,et al.  Reaction properties of catalytic antibodies encapsulated in organo substituted SiO2 sol-gel materials. , 2005, Journal of bioscience and bioengineering.

[127]  M. Goto,et al.  Surface imprinted polymers recognizing amino acid chirality , 2000 .

[128]  Jae-Ho Kim,et al.  Detection of mycoestrogen zearalenone by a molecularly imprinted polypyrrole-based surface plasmon resonance (SPR) sensor. , 2009, Journal of agricultural and food chemistry.

[129]  Albert H. Titus,et al.  Multi-sensor system based on phase detection, an LED array, and luminophore-doped xerogels , 2005 .

[130]  K. Faid,et al.  Synthesis and characterization of functional methacrylate copolymers and their application in molecular imprinting , 2005 .

[131]  Angel Ríos,et al.  Molecularly imprinted polymers for selective piezoelectric sensing of small molecules , 2008 .

[132]  Lei Ye,et al.  Characterization of QCM sensor surfaces coated with molecularly imprinted nanoparticles. , 2008, Biosensors & bioelectronics.

[133]  M. Goto,et al.  Chiral-recognition polymer prepared by surface molecular imprinting technique , 2000 .

[134]  Jing Cheng,et al.  Molecularly Imprinted Silica Nanospheres Embedded CdSe Quantum Dots for Highly Selective and Sensitive Optosensing of Pyrethroids , 2010 .

[135]  K. Mosbach,et al.  Study of the nature of recognition in molecularly imprinted polymers , 1996, Journal of molecular recognition : JMR.

[136]  Chul Oh,et al.  The use of a thermally reversible bond for molecular imprinting of silica spheres. , 2002, Journal of the American Chemical Society.

[137]  Kirsi Tappura,et al.  Lipoate-based imprinted self-assembled molecular thin films for biosensor applications. , 2007, Biosensors & bioelectronics.

[138]  Olof Ramström,et al.  Molecularly Imprinted Materials : Science and Technology , 2004 .

[139]  V. B. Kandimalla,et al.  Molecular imprinting: a dynamic technique for diverse applications in analytical chemistry , 2004, Analytical and bioanalytical chemistry.

[140]  Denis Lagrange,et al.  Combining resonant piezoelectric micromembranes with molecularly imprinted polymers. , 2007, Angewandte Chemie.

[141]  B. Wang,et al.  Building Fluorescent Sensors by Template Polymerization: The Preparation of a Fluorescent Sensor for l-Tryptophan☆ , 1999 .

[142]  V. Owen Sweden — Competitive amperometric morphine sensor based on an agarose immobilized molecularly imprinted polymer , 1995 .

[143]  D. Bunka,et al.  Aptamers come of age – at last , 2006, Nature Reviews Microbiology.

[144]  K. Kurihara,et al.  Supramolecular sensor based on SnO2 electrode modified withoctadecylsilyl monolayer having molecular binding sites , 1987 .

[145]  G. Wulff,et al.  POLYMERIZABLE AMIDINES-ADHESION MEDIATORS AND BINDING SITES FOR MOLECULAR IMPRINTING , 1998 .

[146]  Giovanna Carturan,et al.  Encapsulation of functional cells by sol–gel silica: actual progress and perspectives for cell therapy , 2004 .

[147]  Rongning Liang,et al.  Potentiometric sensing of neutral species based on a uniform-sized molecularly imprinted polymer as a receptor. , 2010, Angewandte Chemie.

[148]  T. Takeuchi,et al.  Surface plasmon resonance sensor using molecularly imprinted polymer for detection of sialic acid. , 2001, Biosensors & bioelectronics.

[149]  Wei Yan,et al.  Molecularly imprinted solid-phase extraction and flow-injection chemiluminescence for trace analysis of 2,4-dichlorophenol in water samples , 2008, Analytical and bioanalytical chemistry.

[150]  Lan Xu,et al.  Electrochemical tolazoline sensor based on gold nanoparticles and imprinted poly-o-aminothiophenol film , 2010 .

[151]  Franz L Dickert,et al.  Bioimprinted QCM sensors for virus detection—screening of plant sap , 2004, Analytical and Bioanalytical Chemistry.

[152]  Vincent M. Rotello,et al.  Fabrication and Self-Optimization of Multivalent Receptors on Nanoparticle Scaffolds , 2000 .

[153]  M. Abo,et al.  Application of capillary electrophoresis to the simultaneous determination of betaines in plants. , 2001, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[154]  C. Gong,et al.  The Fabrication of a Photoresponsive Molecularly Imprinted Polymer for the Photoregulated Uptake and Release of Caffeine , 2006 .

[155]  H. Finklea,et al.  Quartz crystal microbalance sensor for organic vapor detection based on molecularly imprinted polymers. , 2003, Analytical chemistry.

[156]  Hui-Chi Huang,et al.  Photo-lithographically impregnated and molecularly imprinted polymer thin film for biosensor applications. , 2004, Journal of chromatography. A.

[157]  Takaomi Kobayashi,et al.  Molecular imprint membranes prepared by the phase inversion precipitation technique , 1996 .

[158]  K. Haupt,et al.  Hierarchically Nanostructured Polymer Films Based on Molecularly Imprinted Surface‐Bound Nanofilaments , 2007 .

[159]  Roy G. Thompson,et al.  Molecular imprinting of small molecules with organic silanes: Fluorescence detection , 1997 .

[160]  Tse-Chuan Chou,et al.  Determination of albumin concentration by MIP-QCM sensor. , 2004, Biosensors & bioelectronics.

[161]  L. Ye,et al.  Preparation of molecularly imprinted polymers using nitroxide-mediated living radical polymerization. , 2006, Biosensors & bioelectronics.

[162]  J. Lin,et al.  Chemiluminescent flow-through sensor for 1,10-phenanthroline based on the combination of molecular imprinting and chemiluminescence. , 2001, The Analyst.

[163]  David Avnir,et al.  Chiral electrochemical recognition by very thin molecularly imprinted sol-gel films. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[164]  K Mosbach,et al.  Enantiomeric resolution of amino acid derivatives on molecularly imprinted polymers as monitored by potentiometric measurements. , 1990, Journal of chromatography.

[165]  N. Peppas,et al.  Responsive and recognitive hydrogels using star polymers. , 2004, Journal of biomedical materials research. Part A.

[166]  Sergey A. Piletsky,et al.  Rational design of a polymer specific for microcystin-LR using a computational approach. , 2002, Analytical chemistry.

[167]  Rongning Liang,et al.  Potentiometric sensor based on molecularly imprinted polymer for determination of melamine in milk , 2009 .

[168]  G. Wulff,et al.  Enzyme‐analogue built polymers, 4. On the synthesis of polymers containing chiral cavities and their use for the resolution of racemates , 1977 .

[169]  Ellen L. Holthoff,et al.  Molecularly templated materials in chemical sensing. , 2007, Analytica chimica acta.

[170]  David R. Walt,et al.  Miniature Analytical Methods for Medical Diagnostics , 2005, Science.

[171]  K. Mosbach,et al.  Synthesis of substrate‐selective polymers by host‐guest polymerization , 1981 .

[172]  N. Acosta,et al.  Molecularly imprinted chitosan-genipin hydrogels with recognition capacity toward o-xylene. , 2007, Biomacromolecules.

[173]  Shengyang Tao,et al.  Imprinted photonic polymers for chiral recognition. , 2006, Angewandte Chemie.

[174]  Peter A. Lieberzeit,et al.  Artificial Antibodies for Bioanalyte Detection—Sensing Viruses and Proteins , 2006 .

[175]  W. Wang,et al.  Building fluorescent sensors for carbohydrates using template-directed polymerizations. , 2001, Bioorganic chemistry.

[176]  B. Bassler,et al.  Quorum sensing in bacteria. , 2001, Annual review of microbiology.

[177]  Otto S. Wolfbeis,et al.  Electropolymerized Molecularly Imprinted Polymers as Receptor Layers in Capacitive Chemical Sensors , 1999 .

[178]  Itamar Willner,et al.  Imprinting of molecular recognition sites through electropolymerization of functionalized Au nanoparticles: development of an electrochemical TNT sensor based on pi-donor-acceptor interactions. , 2008, Journal of the American Chemical Society.

[179]  Xiao Li,et al.  Two-dimensional molecular imprinting approach to produce optical biosensor recognition elements. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[180]  F. Dickert,et al.  Pollen-imprinted polyurethanes for QCM allergen sensors , 2009, Analytical and bioanalytical chemistry.

[181]  A. Aghaei,et al.  A novel capacitive biosensor for cholesterol assay that uses an electropolymerized molecularly imprinted polymer , 2010 .

[182]  T. Egan,et al.  Nucleation of calcium oxalate crystals on an imprinted polymer surface from pure aqueous solution and urine , 2004, JBIC Journal of Biological Inorganic Chemistry.

[183]  J. Homola Surface plasmon resonance sensors for detection of chemical and biological species. , 2008, Chemical reviews.

[184]  Koji Sode,et al.  Construction of a molecular imprinting catalyst using target analogue template and its application for an amperometric fructosylamine sensor. , 2003, Biosensors & bioelectronics.

[185]  Börje Sellergren,et al.  Molecularly imprinted polymers : man-made mimics of antibodies and their applications in analytical chemistry , 2001 .

[186]  Ida A. Casalinuovo,et al.  Application of Electronic Noses for Disease Diagnosis and Food Spoilage Detection , 2006, Sensors (Basel, Switzerland).

[187]  L. Ye,et al.  Molecularly imprinted monodisperse microspheres for competitive radioassay , 1999 .

[188]  Krishna C Persaud Medical Applications of Odor-Sensing Devices , 2005, The international journal of lower extremity wounds.

[189]  N. Magan,et al.  Electronic noses and disease diagnostics , 2004, Nature Reviews Microbiology.

[190]  David Avnir,et al.  Enzymes and Other Proteins Entrapped in Sol-Gel Materials , 1994 .

[191]  Zhixian Gao,et al.  Quartz crystal microbalance for the detection of carbaryl using molecularly imprinted polymers as recognition element. , 2009, Journal of separation science.

[192]  D. Rathbone,et al.  Tools for fluorescent molecularly imprinted polymers. , 2005, Biosensors & bioelectronics.

[193]  S. Rimmer,et al.  Molecular Recognition of Caffeine by Shell Molecular Imprinted Core–Shell Polymer Particles in Aqueous Media , 2002 .

[194]  M. Ganjali,et al.  A Biomimetic Potentiometric Sensor Using Molecularly Imprinted Polymer for the Cetirizine Assay in Tablets and Biological Fluids , 2008 .

[195]  John D. Bass,et al.  Thermolytic Synthesis of Imprinted Amines in Bulk Silica , 2003 .

[196]  J. Aburto,et al.  Selective Adsorption of Dibenzothiophene Sulfone by an Imprinted and Stimuli-Responsive Chitosan Hydrogel , 2004 .

[197]  Sergey A. Piletsky,et al.  Piezoelectric sensors based on molecular imprinted polymers for detection of low molecular mass analytes , 2007, The FEBS journal.

[198]  Ingemar Lundström,et al.  Some studies of molecularly-imprinted polymer membranes in combination with field-effect devices , 1993 .

[199]  G. D’Agostino,et al.  Molecularly Imprinted Polymer‐Based Sensors for Amperometric Determination of Nonelectroactive Substances , 2009 .

[200]  M. Lam,et al.  A Sol-gel Derived Molecular Imprinted Luminescent PET Sensing Material for 2,4-Dichlorophenoxyacetic Acid , 2001 .

[201]  David C Cullen,et al.  Optical interrogation of molecularly imprinted polymers and development of MIP sensors: a review , 2005, Analytical and bioanalytical chemistry.

[202]  Anthony W. van Buuren,et al.  Functionalized silicon membranes for selective bio-organism capture , 2003, Nature materials.

[203]  Karsten Haupt,et al.  Molecularly imprinted polymers as antibody and receptor mimics for assays, sensors and drug discovery , 2004, Analytical and bioanalytical chemistry.

[204]  B. Sellergren,et al.  Method for synthesis and screening of large groups of molecularly imprinted polymers. , 1999, Analytical chemistry.