Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation
暂无分享,去创建一个
[1] P. Syrris,et al. The Influence of Pharmacogenetics on the Time to Achieve Target Tacrolimus Concentrations after Kidney Transplantation , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[2] W. Weimar,et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR‐1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus , 2003, Clinical pharmacology and therapeutics.
[3] E. Schuetz,et al. Tacrolimus Dosing in Pediatric Heart Transplant Patients is Related to CYP3A5 and MDR1 Gene Polymorphisms , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[4] C. Staatz,et al. Bayesian Forecasting and Prediction of Tacrolimus Concentrations in Pediatric Liver and Adult Renal Transplant Recipients , 2003, Therapeutic drug monitoring.
[5] C. Staatz,et al. Toward better outcomes with tacrolimus therapy: Population pharmacokinetics and individualized dosage prediction in adult liver transplantation , 2003, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[6] Y. Cheung,et al. Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients. , 2003, Pharmacogenetics.
[7] P. Syrris,et al. Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and p-glycoprotein correlate with dose requirement , 2002, Transplantation.
[8] T. Pisitkun,et al. The roles of C4 and AUC0-4 in monitoring of tacrolimus in stable kidney transplant patients. , 2002, Transplantation proceedings.
[9] C. Staatz,et al. Population pharmacokinetics of tacrolimus in adult kidney transplant recipients , 2002, Clinical pharmacology and therapeutics.
[10] E. Schuetz,et al. Genetic contribution to variable human CYP3A-mediated metabolism. , 2002, Advanced drug delivery reviews.
[11] S. McCann,et al. Evaluation of a rapid micro-scale assay for tacrolimus by liquid chromatography-tandem mass spectrometry , 2002, Annals of clinical biochemistry.
[12] N. Undre,et al. Pharmacokinetics of tacrolimus in heart transplantation. , 2002, Transplantation proceedings.
[13] P. Koefoed-Nielsen,et al. Alterations in calcineurin phosphatase activity in tacrolimus-treated renal transplant patients. , 2002, Transplantation proceedings.
[14] Miyuki Kimura,et al. Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P‐glycoprotein , 2002, Clinical pharmacology and therapeutics.
[15] I. Colle,et al. Are reduced tacrolimus dosages needed in the early postoperative period following living donor liver transplantation in adults? , 2002, Transplantation proceedings.
[16] C. Felipe,et al. The impact of ethnic miscegenation on tacrolimus clinical pharmacokinetics and therapeutic drug monitoring , 2002, Clinical transplantation.
[17] N. Undre,et al. Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation. , 2002, Transplantation proceedings.
[18] N. Undre,et al. Pharmacokinetics of tacrolimus in paediatric renal transplant recipients. , 2002, Transplantation proceedings.
[19] M. Christiaans,et al. Evidence that fasting does not significantly affect trough levels of tacrolimus in stable renal transplant recipients. , 2002, Transplantation proceedings.
[20] K. Uchida,et al. Optimal use of tacrolimus in living donor renal transplantation in children. , 2002, Transplantation proceedings.
[21] J. Poulsen,et al. C2 (2-h) levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal-transplant patients. , 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[22] T. Nabeshima,et al. Interference of Hematocrit in the Tacrolimus II Microparticle Enzyme Immunoassay , 2002, Therapeutic drug monitoring.
[23] N. Goto,et al. Usefulness of monitoring of AUC(0-4h) during the induction period of immunosuppressive therapy with tacrolimus after renal transplantation. , 2002, Transplantation proceedings.
[24] E. Schütz,et al. Therapeutic drug monitoring of tacrolimus early after liver transplantation. , 2002, Transplantation proceedings.
[25] K. Takahashi,et al. Study of pharmacokinetic parameters of tacrolimus by different oral administration periods in renal transplantation. , 2002, Transplantation proceedings.
[26] E. Schuetz,et al. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. , 2002, Molecular pharmacology.
[27] G. Mazariegos,et al. Pediatric intestinal transplantation: Historical notes, principles and controversies , 2002, Pediatric transplantation.
[28] M. Oellerich,et al. Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood. , 2002, Clinical chemistry.
[29] J. Hooff,et al. Evaluation of prediction of tacrolimus area under the curve by trough concentrations , 2002 .
[30] K. Resch,et al. Simultaneous Quantification of Sirolimus, Everolimus, Tacrolimus and Cyclosporine by Liquid Chromatography-Mass Spectrometry (LC-MS) , 2002, Clinical chemistry and laboratory medicine.
[31] M. Makuuchi,et al. Correlation between optimal tacrolimus doses and the graft weight in living donor liver transplantation , 2002, Clinical transplantation.
[32] D. Gerber,et al. Tacrolimus dosing requirements and concentrations in adult living donor liver transplant recipients , 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[33] Nancy M. Stolpman,et al. Living donor liver transplant recipients achieve relatively higher immunosuppressant blood levels than cadaveric recipients , 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[34] Atholl Johnston,et al. Therapeutic drug monitoring of immunosuppressant drugs in clinical practice. , 2002, Clinical therapeutics.
[35] B. Bouzas,et al. Replacement of cyclosporine by tacrolimus for immunosuppression in heart transplant patients: safety and efficacy. , 2002, Transplantation proceedings.
[36] J. Poulsen,et al. Blood Tacrolimus Levels and Calcineurin Phosphatase Activity Early after Renal Transplantation , 2002, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[37] A. Tzakis,et al. Intestinal and Multivisceral Transplantation , 2002, World Journal of Surgery.
[38] E. Granot,et al. Abrupt increase of tacrolimus blood levels during an episode of Shigella infection in a child after liver transplantation. , 2001, Therapeutic drug monitoring.
[39] M. Kaneko,et al. Effect of ascites on tacrolimus disposition in a liver transplant recipient. , 2001, Therapeutic drug monitoring.
[40] M. Haberl,et al. The genetic determinants of the CYP3A5 polymorphism. , 2001, Pharmacogenetics.
[41] R. Gaston. Maintenance immunosuppression in the renal transplant recipient: an overview. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[42] J. Poulsen,et al. Optimal time for determination of blood tacrolimus level. , 2001, Transplantation proceedings.
[43] M. Kimikawa,et al. Effective oral administration of tacrolimus in renal transplant recipients , 2001, Clinical transplantation.
[44] C. Staatz,et al. Population pharmacokinetics of tacrolimus in children who receive cut-down or full liver transplants. , 2001, Transplantation.
[45] P Taylor,et al. Low tacrolimus concentrations and increased risk of early acute rejection in adult renal transplantation. , 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[46] H. Saito,et al. Population pharmacokinetics of tacrolimus in adult recipients receiving living-donor liver transplantation , 2001, European Journal of Clinical Pharmacology.
[47] J. Fung,et al. Quantitation of Immunosuppression by Tacrolimus Using Flow Cytometric Analysis of Interleukin-2 and Interferon-&ggr; Inhibition in CD8− and CD8+ Peripheral Blood T Cells , 2001, Therapeutic drug monitoring.
[48] E. Hochleitner,et al. Increased tacrolimus levels during diarrhea , 2001, Transplant international : official journal of the European Society for Organ Transplantation.
[49] B. Meiser,et al. Suggested guidelines for the use of tacrolimus in cardiac transplant recipients. , 2001, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[50] T. Habuchi,et al. Chrono and clinical pharmacokinetic study of tacrolimus in continuous intravenous administration , 2001, International journal of urology : official journal of the Japanese Urological Association.
[51] I. Bekersky,et al. Comparative Tacrolimus Pharmacokinetics: Normal versus Mildly Hepatically Impaired Subjects , 2001, Journal of clinical pharmacology.
[52] A. Okada,et al. Oral administration of tacrolimus in the presence of jejunostomy after liver transplantation , 2001, Pediatric transplantation.
[53] S. Soldin,et al. Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography--tandem mass-spectrometry. , 2001, Clinical biochemistry.
[54] G. Lensmeyer,et al. Therapeutic Monitoring of Tacrolimus Concentrations in Blood: Semi-Automated Extraction and Liquid Chromatography-Electrospray Ionization Mass Spectrometry , 2001, Therapeutic drug monitoring.
[55] Julie A. Johnson,et al. THE EFFECT OF GUT METABOLISM ON TACROLIMUS BIOAVAILABILITY IN RENALTRANSPLANT RECIPIENTS1,2 , 2001, Transplantation.
[56] H. Saito,et al. Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living‐donor liver transplantation , 2001, Clinical pharmacology and therapeutics.
[57] R. Morris,et al. New approach in drug development: whole blood pharmacodynamic assays reflect biological activities of tacrolimus. , 2001, Transplantation proceedings.
[58] M. de Bonis,et al. Tacrolimus as a rescue immunosuppressant after heart transplantation. , 2001, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
[59] L. Shaw,et al. Clinical Utility of Monitoring Tacrolimus Blood Concentrations in Liver Transplant Patients , 2001, Journal of clinical pharmacology.
[60] C. Campañá,et al. Pharmacokinetics of tacrolimus during the early phase after heart transplantation. , 2001, Transplantation proceedings.
[61] H. Reichenspurner,et al. Tacrolimus versus cyclosporine after lung transplantation: a prospective, open, randomized two-center trial comparing two different immunosuppressive protocols. , 2001, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[62] Ann Daly,et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression , 2001, Nature Genetics.
[63] R. Jelliffe,et al. Failure of Traditional Trough Levels to Predict Tacrolimus Concentrations , 2001, Therapeutic drug monitoring.
[64] J. Thompson,et al. Tacrolimus and diarrhea: Pathogenesis of altered metabolism , 2001, Pediatric transplantation.
[65] J. Pirsch,et al. Therapeutic drug monitoring of tacrolimus in pediatric liver transplant patients , 2001, Pediatric transplantation.
[66] R. Margreiter,et al. Rotavirus infection as cause of tacrolimus elevation in solid‐organ‐transplanted children , 2001, Pediatric transplantation.
[67] B. Simma,et al. Elevated tacrolimus trough levels in association with mycophenolate mofetil‐induced diarrhea: A case report , 2001, Pediatric transplantation.
[68] M. Ingelman-Sundberg,et al. Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43. , 2001, Biochemical and biophysical research communications.
[69] I. Bekersky,et al. Effect of Time of Meal Consumption on Bioavailability of a Single Oral 5 mg Tacrolimus Dose , 2001, Journal of clinical pharmacology.
[70] U. Brinkmann,et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. , 2001, Pharmacogenetics.
[71] M. Mehra,et al. Ethnic disparities in the pharmacologic characteristics of tacrolimus in heart transplantation. , 2001, Transplantation proceedings.
[72] C. Felipe,et al. Choosing the right dose of new immunossuppressive drugs for new populations: importance of pharmacokinetic studies. , 2001, Transplantation proceedings.
[73] P. Berloco,et al. Tacrolimus as cornerstone immunosuppressant in kidney transplantation. , 2001, Transplantation proceedings.
[74] W. V. van Son,et al. Prediction of the inhibition of IL-2 production by calcineurin inhibitors. , 2001, Transplantation proceedings.
[75] H. Asanuma,et al. Pharmacokinetics of tacrolimus in pediatric renal transplant recipients. , 2001, Transplantation proceedings.
[76] V. Armstrong,et al. New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine. , 2001, Clinical biochemistry.
[77] I. Bekersky,et al. Effect of Low‐ and High‐Fat Meals on Tacrolimus Absorption following 5 mg Single Oral Doses to Healthy Human Subjects , 2001, Journal of clinical pharmacology.
[78] M. Slooff,et al. Recurrent HCV infection reduces the requirement for tacrolimus after liver transplantation. , 2001, Transplantation proceedings.
[79] J. Halpert,et al. cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450. , 2001, Molecular pharmacology.
[80] C. Manzanares,et al. Covariate Effects on the Apparent Clearance of Tacrolimus in Paediatric Liver Transplant Patients Undergoing Conversion Therapy , 2001, Clinical Pharmacokinetics.
[81] U. Christians,et al. The pharmacokinetics and metabolic disposition of tacrolimus: A comparison across ethnic groups , 2001, Clinical pharmacology and therapeutics.
[82] Paul J. Williams,et al. The Role of Population Pharmacokinetics in Drug Development in Light of the Food and Drug Administration’s ‘Guidance for Industry: Population Pharmacokinetics’ , 2000, Clinical pharmacokinetics.
[83] S. Chan,et al. Population pharmacokinetics of tacrolimus in Asian paediatric liver transplant patients. , 2000, British journal of clinical pharmacology.
[84] Po-Huang Lee,et al. Clinical influencing factors for daily dose, trough level, and relative clearance of tacrolimus in renal transplant recipients. , 2000, Transplantation proceedings.
[85] M. Makuuchi,et al. Correlation between graft size and necessary tacrolimus dose after living-related liver transplantation. , 2000, Transplantation Proceedings.
[86] R. Morris,et al. Pharmacodynamics of immunosuppressive drugs. , 2000, Current opinion in immunology.
[87] P. Taylor,et al. Simultaneous Quantification of Tacrolimus and Sirolimus, in Human Blood, by High-Performance Liquid Chromatography–Tandem Mass Spectrometry , 2000, Therapeutic drug monitoring.
[88] M. Manns,et al. Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants. , 2000, Journal of chromatography. B, Biomedical sciences and applications.
[89] S. Hilsenbeck,et al. Tacrolimus clearance is age-dependent within the pediatric population , 2000, Bone Marrow Transplantation.
[90] V. Furlan,et al. Conversion from cyclosporin A to tacrolimus in pediatric liver transplantation , 2000, Pediatric transplantation.
[91] P. Halloran,et al. Immunophilins may limit calcineurin inhibition by cyclosporine and tacrolimus at high drug concentrations. , 2000, Transplantation.
[92] G. Yanik,et al. Tacrolimus (FK506) and methotrexate as prophylaxis for acute graft-versus-host disease in pediatric allogeneic stem cell transplantation , 2000, Bone Marrow Transplantation.
[93] S. Uemoto,et al. Effect of intestinal P‐glycoprotein on daily tacrolimus trough level in a living‐donor small bowel recipient , 2000, Clinical pharmacology and therapeutics.
[94] G. Mazariegos,et al. Long-term results after conversion from cyclosporine to tacrolimus in pediatric liver transplantation for acute and chronic rejection. , 2000, Transplantation.
[95] R. Jindal,et al. Towards a specific immunosuppression for pancreas and islet grafts , 2000, Clinical transplantation.
[96] R. J. Dumont,et al. Methods for Clinical Monitoring of Cyclosporin in Transplant Patients , 2000, Clinical pharmacokinetics.
[97] C. Shek,et al. Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. , 2000, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[98] J. Fung,et al. QUANTITATION OF IMMUNOSUPPRESSION BY FK506 USING FLOW CYTOMETRIC ANALYSIS OF IL‐2 AND INF‐&ggr; INHIBITION IN PERIPHERAL BLOOD T CELLS.: Abstract# 1081 , 2000 .
[99] U. Brinkmann,et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[100] L. Kennedy,et al. Tacrolimus: An Alternative for Graft-Versus-Host Disease Prevention , 2000, The Annals of pharmacotherapy.
[101] G. Plosker,et al. Tacrolimus: a further update of its pharmacology and therapeutic use in the management of organ transplantation. , 2000, Drugs.
[102] M. Christensen,et al. Increased tacrolimus levels in a pediatric renal transplant patient attributed to chronic diarrhea , 2000, Pediatric transplantation.
[103] G. Kearns,et al. Cytochrome P450 3A , 1999, Clinical pharmacokinetics.
[104] J. Wingard,et al. Increased clearance of tacrolimus in children: need for higher doses and earlier initiation prior to bone marrow transplantation , 1999, Bone Marrow Transplantation.
[105] M. Christiaans,et al. Dosing and management guidelines for tacrolimus in renal transplant patients. , 1999, Transplantation proceedings.
[106] M. Rela,et al. Oral absorption of tacrolimus in children with intestinal failure due to short or absent small bowel , 1999, Transplant international : official journal of the European Society for Organ Transplantation.
[107] Y Zhang,et al. Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[108] A. Mayer. Four-year follow-up of the European Tacrolimus Multicenter Renal Study. , 1999, Transplantation proceedings.
[109] G. Burckart,et al. P‐glycoprotein and Drug Therapy in Organ Transplantation , 1999, Journal of clinical pharmacology.
[110] L. Rostaing,et al. Differences in Type 1 and Type 2 intracytoplasmic cytokines, detected by flow cytometry, according to immunosuppression (cyclosporine A vs. tacrolimus) in stable renal allograft recipients , 1999, Clinical transplantation.
[111] L. Shaw,et al. Current opinions on therapeutic drug monitoring of immunosuppressive drugs. , 1999, Clinical therapeutics.
[112] R. Shapiro,et al. Tacrolimus in solid organ transplantation: an update. , 1999, Transplantation proceedings.
[113] G. Tydén,et al. Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. , 1999, British journal of clinical pharmacology.
[114] J. Briegel,et al. Optimization of the immunosuppressive protocol after lung transplantation. , 1999, Transplantation.
[115] F. J. Fricker,et al. Tacrolimus-based triple-drug immunosuppression minimizes serum lipid elevations in pediatric cardiac transplant recipients. , 1999, The Journal of Heart and Lung Transplantation.
[116] J. Briegel,et al. Tacrolismus (FK506) as Primary Immunosuppressant After Lung Transplantation , 1999 .
[117] N. Undre,et al. The disposition of 14C-labeled tacrolimus after intravenous and oral administration in healthy human subjects. , 1999, Drug metabolism and disposition: the biological fate of chemicals.
[118] S. Yamaguchi,et al. No ethnic difference between Caucasian and Japanese hepatic samples in the expression frequency of CYP3A5 and CYP3A7 proteins. , 1999, Biochemical pharmacology.
[119] Cherylee W. J. Chang. Neurologic complications of critical illness and transplantation , 1999 .
[120] D. Renlund,et al. A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus. , 1999, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[121] B. Griffith,et al. Posttransplant diabetes mellitus in pediatric thoracic organ recipients receiving tacrolimus-based immunosuppression. , 1999 .
[122] J. Fay,et al. Relationship of tacrolimus whole blood levels to efficacy and safety outcomes after unrelated donor marrow transplantation. , 1999, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[123] M. Henry. Cyclosporine and tacrolimus (FK506): A comparison of efficacy and safety profiles , 1999, Clinical transplantation.
[124] E. Trulock,et al. Suggested guidelines for the use of tacrolimus in lung-transplant recipients. , 1999, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[125] J. Hooff,et al. Low systemic exposure to tacrolimus correlates with acute rejection. , 1999, Transplantation proceedings.
[126] R. Stratta. Optimal immunosuppression in pancreas transplantation. , 1999, Transplantation proceedings.
[127] C. Esquivel,et al. Long‐term outcomes in pediatric liver recipients: Comparison between cyclosporin A and tacrolimus , 1999, Pediatric transplantation.
[128] E. Arbustini,et al. Clinical pharmacokinetics of tacrolimus in heart transplant recipients. , 1999, Therapeutic drug monitoring.
[129] M. Abecassis,et al. Low bioavailability of cyclosporine microemulsion and tacrolimus in a small bowel transplant recipient: possible relationship to intestinal P-glycoprotein activity. , 1999, Transplantation.
[130] R. M. Fisher,et al. Effects of Rifampin on Tacrolimus Pharmacokinetics in Healthy Volunteers , 1999, Journal of clinical pharmacology.
[131] J. Pirsch,et al. The role of tacrolimus in adult kidney transplantation: a review. , 1998, Clinical transplantation.
[132] R. Shapiro,et al. Tacrolimus in pediatric renal transplantation: a review. , 1998, Pediatric transplantation.
[133] Y Zhang,et al. Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics. , 1998, Journal of pharmaceutical sciences.
[134] S. Kawasaki,et al. Relationship between in vivo FK506 clearance and in vitro 13-demethylation activity in living-related liver transplantation. , 1998, Transplantation.
[135] T. Starzl,et al. Pediatric renal transplantation under tacrolimus-based immunosuppression. , 1998, Transplantation.
[136] T. Schnider,et al. Expanding clinical applications of population pharmacodynamic modelling. , 1998, British journal of clinical pharmacology.
[137] R. Yatscoff,et al. The monitoring of immunosuppressive drugs: a pharmacodynamic approach. , 1998, Therapeutic drug monitoring.
[138] A. Nademanee,et al. Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. , 1998, Blood.
[139] T. Starzl,et al. LONG-TERM RESULTS OF PANCREAS TRANSPLANTATION UNDER TACROLIMUS IMMUNOSUPPRESSION , 1998 .
[140] P. Jara,et al. Monitoring of tacrolimus as rescue therapy in pediatric liver transplantation. , 1998, Therapeutic drug monitoring.
[141] R. Busuttil,et al. Tacrolimus is superior to cyclosporine in liver transplantation. , 1998, Transplantation proceedings.
[142] P. Halloran,et al. Calcineurin and the biological effect of cyclosporine and tacrolimus. , 1998, Transplantation proceedings.
[143] A. Davenport,et al. Oxidizability of low-density lipoproteins from Neoral and tacrolimus-treated renal transplant patients. , 1998, Transplantation proceedings.
[144] L. Benet. Impact of intraindividual variability of drugs on therapeutic outcomes: lessons from outside transplantation. , 1998, Transplantation proceedings.
[145] G. Patterson,et al. Tacrolimus therapy for persistent or recurrent acute rejection after lung transplantation. , 1998, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[146] Nicholas H. G. Holford,et al. Population Pharmacokinetics and Pharmacodynamics: An Underutilized Resource , 1998 .
[147] L. Shaw,et al. THERAPEUTIC DRUG MONITORING OF CYCLOSPORINE AND TACROLIMUS , 1998 .
[148] T. Starzl,et al. Liver transplantation under tacrolimus in infants, children, adults, and seniors: long-term results, survival, and adverse events in 1000 consecutive patients. , 1998, Transplantation proceedings.
[149] J. Barkun,et al. Optimal time points for the prediction of the area-under-the-curve in liver transplant patients receiving tacrolimus. , 1998, Transplantation proceedings.
[150] G. Ramadori,et al. Tacrolimus and mycophenolate mofetil in clinical liver transplantation: experience with a steroid-sparing concept. , 1998, Transplantation proceedings.
[151] J. Fung,et al. Comparison of Tacrolimus Absorption in Transplant Patients Receiving Continuous versus Interrupted Enteral Nutritional Feeding , 1998, The Annals of pharmacotherapy.
[152] I. Bekersky,et al. Demographic considerations in tacrolimus pharmacokinetics. , 1998, Transplantation proceedings.
[153] J. Neylan. Effect of race and immunosuppression in renal transplantation: three-year survival results from a US multicenter, randomized trial. FK506 Kidney Transplant Study Group. , 1998, Transplantation proceedings.
[154] P. Stock,et al. Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. , 1998, Clinical transplantation.
[155] M. Yacoub,et al. Clinical use and bioavailability of tacrolimus in heart-lung and double lung transplant recipients with cystic fibrosis. , 1998, Transplantation proceedings.
[156] J. Segura,et al. Influence of hepatitis C virus infection on FK 506 blood levels in renal transplant patients. , 1998, Transplantation proceedings.
[157] H. Palevsky,et al. Conversion to tacrolimus (FK506) from cyclosporine after orthotopic lung transplantation. , 1998, Transplantation proceedings.
[158] W. V. van Son,et al. Quantification of immunosuppression by flow cytometric measurement of intracellular cytokine synthesis , 1998, Transplant international : official journal of the European Society for Organ Transplantation.
[159] W. Padberg,et al. Improvement of nephrotoxicity, hypertension, and lipid metabolism after conversion of kidney transplant recipients from cyclosporine to tacrolimus. , 1998, Transplantation proceedings.
[160] T. Miki,et al. Low-dose tacrolimus (FK506)-based immunosuppressive protocol in living donor renal transplantation , 1998 .
[161] M. Brunet,et al. Influence of posttransplant time on dose and concentration of tacrolimus in liver transplant patients , 1998, Transplant international : official journal of the European Society for Organ Transplantation.
[162] T. Starzl,et al. Incidence Of End-Stage Renal Failure Amongst Long-term Survival Of Primary Liver Transplant Recipients Under Tacrolimus: Adults and Children , 1998 .
[163] D. Min,et al. An abbreviated area-under-the-curve monitoring for tacrolimus in patients with liver transplants. , 1998, Therapeutic drug monitoring.
[164] M. Moxey-Mims,et al. Increased incidence of insulin-dependent diabetes mellitus in pediatric renal transplant patients receiving tacrolimus (FK506) , 1998, Transplantation.
[165] A. Trull. Therapeutic Monitoring of Tacrolimus , 1998, Annals of clinical biochemistry.
[166] J. Skyler,et al. Cholesterol control: long-term benefit of pancreas-kidney transplantation with FK 506 immunosuppression. , 1998, Transplantation proceedings.
[167] J. Neylan. Racial differences in renal transplantation after immunosuppression with tacrolimus versus cyclosporine. FK506 Kidney Transplant Study Group. , 1998, Transplantation.
[168] A. Gaber,et al. Effects of tacrolimus on hyperlipidemia after successful renal transplantation: a Southeastern Organ Procurement Foundation multicenter clinical study. , 1998, Transplantation.
[169] A. Grygotis,et al. High-performance liquid chromatography-tandem mass spectrometry as a reference for analysis of tacrolimus to assess two immunoassays in patients with liver and renal transplants. , 1997, Therapeutic drug monitoring.
[170] D. Shen,et al. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. , 1997, The Journal of pharmacology and experimental therapeutics.
[171] K. Goa,et al. Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation. , 1997, Drugs.
[172] H. Antunes,et al. Early signs and risk factors for the increased incidence of Epstein-Barr virus-related posttransplant lymphoproliferative diseases in pediatric liver transplant recipients treated with tacrolimus. , 1997, Transplantation.
[173] J. Farrant,et al. Determination of intracellular cytokines by flow-cytometry following whole-blood culture. , 1997, Journal of immunological methods.
[174] B. Erbslöh-Möller,et al. Effect of FK506 on magnesium homeostasis after renal transplantation. , 1997, Transplantation proceedings.
[175] Hébert. Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. , 1997, Advanced drug delivery reviews.
[176] A. Alak,et al. An HPLC/MS/MS assay for tacrolimus in patient blood samples. Correlation with results of an ELISA assay. , 1997, Journal of pharmaceutical and biomedical analysis.
[177] Morton B. Brown,et al. Role of intestinal P‐glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine , 1997, Clinical pharmacology and therapeutics.
[178] T. Starzl,et al. Pregnancy after liver transplantation under tacrolimus. , 1997, Transplantation.
[179] J. Squifflet,et al. Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection - A report of the European Tacrolimus Multicenter Renal Study Group , 1997 .
[180] A. Alak,et al. Biological activity of tacrolimus (FK506) and its metabolites from whole blood of kidney transplant patients. , 1997, Transplantation proceedings.
[181] R. Gruessner,et al. Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group. , 1997, Clinical transplantation.
[182] Q. Zhang,et al. A specific method for the measurement of tacrolimus in human whole blood by liquid chromatography/tandem mass spectrometry. , 1997, Therapeutic drug monitoring.
[183] R. Wiesner,et al. Evolution of cardiovascular risk after liver transplantation: a comparison of cyclosporine A and tacrolimus (FK506). , 1997, Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[184] Joshua Miller,et al. A Comparison Of Tacrolimus (fk506) And Cyclosporine For Immunosuppression After Cadaveric Renal Transplantation1 , 1997 .
[185] R. Jindal,et al. Post-Transplant Diabetes Mellitus , 1997, Drug safety.
[186] C. Mignat,et al. Clinically Significant Drug Interactions with New Immunosuppressive Agents , 1997, Drug safety.
[187] W. Bechstein,et al. Cardiovascular risk factors in long-term follow-up after orthotopic liver transplantation. , 1997, Clinical transplantation.
[188] S. Kawasaki,et al. Apparently increased trough levels of tacrolimus caused by acute infantile diarrhea in two infants with biliary atresia after liver transplantation , 1996, Acta paediatrica Japonica : Overseas edition.
[189] A. Fabrega,et al. Circadian variation of tacrolimus disposition in liver allograft recipients. , 1996, Transplantation.
[190] A. Matas,et al. An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group. , 1996, Transplantation.
[191] R. Kershner,et al. Relationship of FK506 whole blood concentrations and efficacy and toxicity after liver and kidney transplantation. , 1996, Transplantation.
[192] G. Wilkinson. Cytochrome P4503A (CYP3A) metabolism: Prediction ofIn Vivo activity in humans , 1996, Journal of pharmacokinetics and biopharmaceutics.
[193] B. Ring,et al. The human drug metabolizing cytochromes P450 , 1996, Journal of Pharmacokinetics and Biopharmaceutics.
[194] U. Christians,et al. Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. , 1996, Clinical chemistry.
[195] H. Koeppen,et al. Posttransplant lymphoproliferative disease in pediatric liver transplantation. Interplay between primary Epstein-Barr virus infection and immunosuppression. , 1996, Transplantation.
[196] P. Neuhaus,et al. Two‐year data from the European multicentre tacrolimus (F 06) liver study , 1996, Transplant international : official journal of the European Society for Organ Transplantation.
[197] Y. Yamaoka,et al. Pharmacokinetics of FK 506 in living-related liver transplantation. , 1996, Transplantation proceedings.
[198] C. Esquivel,et al. Oral tacrolimus (FK506) induction therapy in pediatric orthotopic liver transplantation. , 1996, Transplantation.
[199] R. Collins,et al. FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation. , 1996, Blood.
[200] B. Griffith,et al. Tacrolimus (FK 506) in clinical cardiac transplantation: a five-year experience. , 1996, Transplantation proceedings.
[201] R. Stratta,et al. FK 506 induction and rescue therapy in pancreas transplant recipients. , 1996, Transplantation proceedings.
[202] U. Christians,et al. Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber , 1996, British journal of pharmacology.
[203] P. Colombani,et al. Suggested guidelines for the use of tacrolimus in pediatric liver transplant patients. , 1996, Transplantation.
[204] G. Klintmalm,et al. General guidelines for the use of tacrolimus in adult liver transplant patients. , 1996, Transplantation.
[205] U. Christians,et al. Identification of drugs inhibiting the in vitro metabolism of tacrolimus by human liver microsomes. , 1996, British journal of clinical pharmacology.
[206] M. A. Moseley,et al. CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells. , 1996, Drug metabolism and disposition: the biological fate of chemicals.
[207] P. Halloran,et al. Molecular mechanisms of new immunosuppressants. , 1996, Clinical transplantation.
[208] F. Aweeka,et al. The Use of Therapeutic Drug Monitoring to Optimise Immunosuppressive Therapy , 1996, Clinical pharmacokinetics.
[209] Y. Yamaoka,et al. The evolution of immunosuppression with FK506 in pediatric living-related liver transplantation. , 1996, Transplantation.
[210] D. Metcalfe,et al. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. , 1995, Journal of immunological methods.
[211] W. Jusko. Analysis of Tacrolimus (FK 506) in Relation to Therapeutic Drug Monitoring , 1995, Therapeutic drug monitoring.
[212] A. Thomson,et al. Mode of Action of Tacrolimus (FK506): Molecular and Cellular Mechanisms , 1995, Therapeutic drug monitoring.
[213] U. Christians,et al. Consensus Document: Therapeutic Monitoring of Tacrolimus (FK‐506) , 1995 .
[214] T. Starzl,et al. Clinical Pharmacokinetics of Tacrolimus , 1995, Clinical pharmacokinetics.
[215] P. Mcmaster,et al. Therapeutic Drug Monitoring of Tacrolimus in Clinical Transplantation , 1995, Therapeutic drug monitoring.
[216] U. Christians,et al. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. , 1995, Drug metabolism and disposition: the biological fate of chemicals.
[217] L. Makowka,et al. A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression in liver transplantation: The U.S. Multicenter FK506 Liver Study Group. N Engl J Med 1994;331:1110–1115 , 1995 .
[218] V. Maino,et al. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. , 1995, Blood.
[219] D. Ellis. Clinical use of tacrolimus (FK-506) in infants and children with renal transplants , 1995, Pediatric Nephrology.
[220] T. Starzl,et al. 133 PHARMACOKINETICS OF TACROLIMUS (TAC) IN TRANSPLANT PATIENTS , 1995 .
[221] R. Venkataramanan,et al. Tacrolimus: a new immunosuppressive agent. , 1995, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
[222] U. Christians,et al. A Risk-Benefit Assessment of Tacrolimus in Transplantation , 1995, Drug safety.
[223] F. J. Fricker,et al. Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506. , 1995, Journal of the American College of Cardiology.
[224] Wojciech Piekoszewski,et al. Pharmacokinetics of tacrolimus in liver transplant patients , 1995, Clinical pharmacology and therapeutics.
[225] D. Buell,et al. FK 506 in liver transplantation: correlation of whole blood levels with efficacy and toxicity. The US Multicenter FK 506 Dose Optimization. , 1995, Transplantation proceedings.
[226] G. Klintmalm,et al. Hyperlipidemia after liver transplantation: long-term results of the FK506/cyclosporine A US Multicenter Trial. US Multicenter Study Group. , 1995, Transplantation proceedings.
[227] G. Klintmalm,et al. Whole-blood and plasma levels of FK 506 after liver transplantation: results from the US Multicenter Trial. FK506 Multicenter Study Group. , 1995, Transplantation proceedings.
[228] Y. Yamaoka,et al. Pharmacokinetics and pharmacodynamics of FK 506 in pediatric patients receiving living-related donor liver transplantations. , 1995, Transplantation proceedings.
[229] U. Christians,et al. Comparison of plasma vs whole blood as matrix for FK 506 drug level monitoring. , 1995, Transplantation proceedings.
[230] G. Gores,et al. Early cellular rejection after orthotopic liver transplantation correlates with low concentrations of FK506 in hepatic tissue , 1995, Hepatology.
[231] P. Neuhaus,et al. Optimal FK 506 dosage in patients under primary immunosuppression following liver transplantation , 1994, Transplant international : official journal of the European Society for Organ Transplantation.
[232] U. Christians,et al. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA). , 1994, British journal of clinical pharmacology.
[233] W. Bechstein,et al. Severe neurotoxicity after liver transplantation: association between FK 506 therapy and hepatitis C virus disease. , 1994, Transplantation proceedings.
[234] Sewing Kf. Pharmacokinetics, dosing principles, and blood level monitoring of FK506. , 1994 .
[235] S. Takahara,et al. Clinical evaluation of trough levels and area under the curve in cyclosporine- and FK 506-treated kidney transplant recipients. , 1994, Transplantation proceedings.
[236] B. Karanam,et al. FK 506 metabolism in human liver microsomes: investigation of the involvement of cytochrome P450 isozymes other than CYP3A4. , 1994, Drug metabolism and disposition: the biological fate of chemicals.
[237] S. Gruber,et al. Pharmacokinetics of FK506 After Intravenous and Oral Administration in Patients Awaiting Renal Transplantation , 1994, Journal of clinical pharmacology.
[238] S. Takahara,et al. Monitoring of FK 506 blood levels in kidney transplant recipients. , 1994, Transplantation proceedings.
[239] J. Reyes,et al. FK 506 in small bowel transplant recipients: pharmacokinetics and dosing. , 1994, Transplantation proceedings.
[240] A Radbruch,et al. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin‐10 in interferon‐γ and in interleukin‐4‐expressing cells , 1994, European journal of immunology.
[241] T. Starzl,et al. FK 506 (Tacrolimus) metabolism by rat liver microsomes and its inhibition by other drugs. , 1994, Research communications in chemical pathology and pharmacology.
[242] G. Klintmalm,et al. FK506 trough levels in whole blood and plasma in liver transplant recipients. Correlation with clinical events and side effects. , 1994, Transplantation.
[243] D. F. Roberts,et al. Age at menarche , 1994, The Lancet.
[244] K. Noda,et al. Distribution and Protein Binding of FK506, a Potent Immunosuppressive Macrolide Lactone, in Human Blood and Its Uptake by Erythrocytes , 1994, The Journal of pharmacy and pharmacology.
[245] P. Beaune,et al. RELATIONSHIP BETWEEN GRAFT CYTOCHROME P‐450 3A CONTENT AND EARLY MORBIDITY AFTER LIVER TRANSPLANTATION1 , 1993, Transplantation.
[246] K. Iwasaki,et al. Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone. , 1993, Drug metabolism and disposition: the biological fate of chemicals.
[247] G. Krejs,et al. Increased susceptibility for CsA-induced hepatotoxicity in kidney graft recipients with chronic viral hepatitis C. , 1993, Transplantation.
[248] K. Iwasaki,et al. Effects of twenty-three drugs on the metabolism of FK506 by human liver microsomes. , 1993, Research communications in chemical pathology and pharmacology.
[249] D. Faulds,et al. Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. , 1993, Drugs.
[250] W. Jusko,et al. Disposition of tacrolimus (FK 506) in rabbits. Role of red blood cell binding in hepatic clearance. , 1993, Drug metabolism and disposition: the biological fate of chemicals.
[251] T. Starzl,et al. Pharmacokinetics of FK506 in Liver Transplant Recipients After Continuous Intravenous Infusion , 1993, Journal of clinical pharmacology.
[252] R. Busuttil,et al. DIFFERENCES IN ORAL FK506 DOSE REQUIREMENTS BETWEEN ADULT AND PEDIATRIC LIVER TRANSPLANT PATIENTS , 1993, Transplantation.
[253] C. Heusser,et al. Detection of intracellular cytokines by flow cytometry. , 1993, Journal of immunological methods.
[254] S. Uemoto,et al. EXPERIENCE WITH FK506 IN LIVING‐RELATED LIVER TRANSPLANTATION , 1993, Transplantation.
[255] T. Starzl,et al. Two-year experience with FK 506 in pediatric patients. , 1993, Transplantation proceedings.
[256] H. Schiebel,et al. Specific and sensitive measurement of FK506 and its metabolites in blood and urine of liver-graft recipients. , 1992, Clinical chemistry.
[257] U. Christians,et al. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. , 1992, Drug metabolism and disposition: the biological fate of chemicals.
[258] T. Starzl,et al. Intravenous, oral pharmacokinetics, and oral dosing of FK 506 in small bowel transplant patients. , 1992, Transplantation proceedings.
[259] A. Gasbarrini,et al. FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. , 1992, The Italian journal of gastroenterology.
[260] A H Thomson,et al. Bayesian Parameter Estimation and Population Pharmacokinetics , 1992, Clinical pharmacokinetics.
[261] Michael A. Schmidt,et al. High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. , 1991, Transplantation proceedings.
[262] M. Kobayashi,et al. FK 506 assay past and present--characteristics of FK 506 ELISA. , 1991, Transplantation proceedings.
[263] T. Starzl,et al. Comparative study of cyclosporine and FK 506 dosage requirements in adult and pediatric orthotopic liver transplant patients. , 1991, Transplantation proceedings.
[264] W. Jusko,et al. Monitoring FK 506 concentrations in plasma and whole blood. , 1991, Transplantation proceedings.
[265] J. Kay,et al. Uptake of FK 506 by lymphocytes and erythrocytes. , 1991, Transplantation proceedings.
[266] C. Groth,et al. Pharmacokinetics of FK 506 during maintenance therapy in liver transplant patients. , 1991, Transplantation proceedings.
[267] T. Starzl,et al. Pharmacokinetics of FK 506 in transplant patients. , 1991, Transplantation proceedings.
[268] S. Todo,et al. Correlation of rejection episodes with FK 506 dosage, FK 506 level, and steroids following primary orthotopic liver transplant. , 1991, Transplantation proceedings.
[269] D. V. van Thiel,et al. Neurologic complications of FK 506. , 1991, Transplantation proceedings.
[270] G. Kootstra,et al. FK 506: monitoring in plasma or in whole blood? , 1991, Transplantation proceedings.
[271] Fung,et al. Practical aspects of FK 506 analysis (Pittsburgh experience). , 1991, Transplantation proceedings.
[272] S. Takahara,et al. Effect of temperature and hematocrit on plasma concentration of FK 506. , 1991, Transplantation proceedings.
[273] T. Starzl,et al. Strategy of FK 506 therapy in liver transplant patients: effect of graft function. , 1991, Transplantation proceedings.
[274] T. Starzl,et al. THE EFFECT OF GRAFT FUNCTION ON FK506 PLASMA LEVELS, DOSAGES, AND RENAL FUNCTION, WITH PARTICULAR REFERENCE TO THE LIVER , 1991, Transplantation.
[275] H. Schiebel,et al. Isolation of an immunosuppressive metabolite of FK506 generated by human microsome preparations. , 1991, Clinical biochemistry.
[276] S. Todo,et al. Pharmacokinetics of FK 506 following oral administration: a comparison of FK 506 and cyclosporine. , 1991, Transplantation proceedings.
[277] T. Starzl,et al. Use of FK 506 in pediatric patients. , 1991, Transplantation proceedings.
[278] H. Schiebel,et al. Measurement of FK 506 by HPLC and isolation and characterization of its metabolites. , 1991, Transplantation proceedings.
[279] S. Todo,et al. Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls. , 1991, Transplantation proceedings.
[280] S. Wrighton,et al. Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). , 1990, Molecular pharmacology.
[281] P. Beaune,et al. Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. , 1990, The Journal of pharmacology and experimental therapeutics.
[282] S. Todo,et al. The effects of FK 506 on renal function after liver transplantation. , 1990, Transplantation proceedings.
[283] J J Fung,et al. Pharmacokinetics of FK 506: preclinical and clinical studies. , 1990, Transplantation proceedings.
[284] S. Todo,et al. Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations. , 1990, Transplantation proceedings.
[285] J. Schuetz,et al. Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver. , 1989, Archives of biochemistry and biophysics.
[286] U. Andersson,et al. Enumeration of IFN-?-producing cells by flow cytometryComparison with fluorescence microscopy , 1988 .
[287] T. Starzl,et al. Drug‐Binding Proteins in Liver Transplant Patients , 1988, Journal of clinical pharmacology.
[288] L. Sheiner,et al. Estimation of population characteristics of pharmacokinetic parameters from routine clinical data , 1977, Journal of Pharmacokinetics and Biopharmaceutics.
[289] Jiunn H. Lin,et al. Role of P-Glycoprotein in Pharmacokinetics , 2003, Clinical pharmacokinetics.
[290] D. Holt,et al. The Pharmacogenetics of Immunosuppression for Organ Transplantation , 2003 .
[291] T. Gelder. Drug Interactions with Tacrolimus , 2002 .
[292] U. Christians,et al. Mechanisms of Clinically Relevant Drug Interactions Associated with Tacrolimus , 2002, Clinical pharmacokinetics.
[293] P. Wallemacq,et al. Comparative Clinical Pharmacokinetics of Tacrolimus in Paediatric and Adult Patients , 2001, Clinical pharmacokinetics.
[294] D. Kelly,et al. Immunosuppressive Drugs in Paediatric Liver Transplantation , 2001, Paediatric drugs.
[295] Y Zhang,et al. The Gut as a Barrier to Drug Absorption , 2001, Clinical pharmacokinetics.
[296] T. Rebbeck,et al. More about: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. , 2000, Journal of the National Cancer Institute.
[297] J. Hooff,et al. Tacrolimus dosing requirements in diabetic and nondiabetic patients calculated from pretransplantation data. , 1998, Transplantation proceedings.
[298] J. Fay,et al. Tacrolimus pharmacokinetics in BMT patients , 1998, Bone Marrow Transplantation.
[299] J. Squifflet,et al. Lipoprotein patterns in renal transplant patients: a comparison between FK 506 and cyclosporine A patients. , 1998, Transplantation proceedings.
[300] N. Undre,et al. Factors affecting the pharmacokinetics of tacrolimus in the first year after renal transplantation. European Tacrolimus Multicentre Renal Study Group. , 1998, Transplantation proceedings.
[301] J. Hooff,et al. Effect of breakfast on the oral bioavailability of tacrolimus and changes in pharmacokinetics at different times posttransplant in renal transplant recipients. , 1998, Transplantation proceedings.
[302] J. Uberti,et al. Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation , 1998, Bone Marrow Transplantation.
[303] S. McDiarmid. The use of tacrolimus in pediatric liver transplantation. , 1998, Journal of pediatric gastroenterology and nutrition.
[304] T. Bieber,et al. FK-506/Tacrolimus , 1997 .
[305] F. Guengerich,et al. Interactions of FK506 (tacrolimus) with clinically important drugs. , 1996, Research communications in molecular pathology and pharmacology.
[306] K. Iwasaki,et al. Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506. , 1995, Drug metabolism and disposition: the biological fate of chemicals.
[307] G. Gores,et al. Other clinical studyEarly cellular rejection after orthotopic liver transplantation correlates with low concentrations of FK506 in hepatic tissue , 1995 .
[308] D. Steinmuller. FK506 and organ transplantation , 1994 .
[309] S. Todo,et al. FK506 and pregnancy in liver transplant patients. , 1993, Transplantation.
[310] Nicholls Mg,et al. The complications of newer transplant antirejection drugs: treatment with cyclosporin A, OKT3, and FK506. , 1990 .
[311] I. Pastan,et al. Expression of a multidrug-resistance gene in human tumors and tissues. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[312] A. Karim. The pharmacokinetics of Norpace. , 1975, Angiology.