Erbin inhibits TGF-β1-induced EMT in renal tubular epithelial cells through an ERK-dependent pathway

[1]  S. Ge,et al.  Role of Sema4C in TGF-β1-induced mitogen-activated protein kinase activation and epithelial–mesenchymal transition in renal tubular epithelial cells , 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[2]  A. Kapus,et al.  Smaddening Complexity: The Role of Smad3 in Epithelial-Myofibroblast Transition , 2010, Cells Tissues Organs.

[3]  H. Nakano,et al.  Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3 , 2010, The Journal of cell biology.

[4]  A. McMahon,et al.  Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. , 2010, The American journal of pathology.

[5]  Wenhua Zheng,et al.  Smad linker region phosphorylation in the regulation of extracellular matrix synthesis , 2010, Cellular and Molecular Life Sciences.

[6]  Kohei Miyazono,et al.  Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. , 2009, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

[7]  Ying E Zhang,et al.  Non-Smad pathways in TGF-β signaling , 2009, Cell Research.

[8]  K. Meldrum,et al.  Cytokines in epithelial-mesenchymal transition: a new insight into obstructive nephropathy. , 2008, The Journal of urology.

[9]  Robert A. Weinberg,et al.  Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. , 2008, Developmental cell.

[10]  A. Djamali,et al.  Epithelial-to-mesenchymal transition and chronic allograft tubulointerstitial fibrosis. , 2008, Transplantation reviews.

[11]  C. Heldin,et al.  Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression , 2007, Cancer science.

[12]  L. Mei,et al.  Erbin Inhibits Transforming Growth Factor β Signaling through a Novel Smad-Interacting Domain , 2007, Molecular and Cellular Biology.

[13]  H. Nakano,et al.  Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway. , 2007, Molecular biology of the cell.

[14]  K. Moelling,et al.  Interaction partners of the PDZ domain of erbin. , 2006, Protein and peptide letters.

[15]  E. Kremmer,et al.  Role for Erbin in Bacterial Activation of Nod2 , 2006, Infection and Immunity.

[16]  L. Mei,et al.  Erbin Inhibits RAF Activation by Disrupting the Sur-8-Ras-Raf Complex* , 2006, Journal of Biological Chemistry.

[17]  M. Nangaku.  Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. , 2005, Journal of the American Society of Nephrology : JASN.

[18]  D. Birnbaum,et al.  Junctional recruitment of mammalian Scribble relies on E-cadherin engagement , 2005, Oncogene.

[19]  Hong-Jian Zhu,et al.  Role of ERK1/2 and p38 mitogen-activated protein kinases in the regulation of thrombospondin-1 by TGF-beta1 in rat proximal tubular cells and mouse fibroblasts. , 2005, Journal of the American Society of Nephrology : JASN.

[20]  J. Borg,et al.  Erbin Regulates Mitogen-activated Protein (MAP) Kinase Activation and MAP Kinase-dependent Interactions between Merlin and Adherens Junction Protein Complexes in Schwann Cells* , 2005, Journal of Biological Chemistry.

[21]  S. Uh,et al.  Role of Reactive Oxygen Species in TGF-β1-Induced Mitogen-Activated Protein Kinase Activation and Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells , 2005 .

[22]  S. Uh,et al.  Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. , 2005, Journal of the American Society of Nephrology : JASN.

[23]  C. McCulloch,et al.  Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. , 2004, The American journal of pathology.

[24]  H. Moses,et al.  Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. , 2004, Neoplasia.

[25]  Youhua Liu.  Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. , 2004, Journal of the American Society of Nephrology : JASN.

[26]  L. Mei,et al.  Erbin Suppresses the MAP Kinase Pathway* , 2003, The Journal of Biological Chemistry.

[27]  M. Rastaldi,et al.  Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. , 2002, Kidney international.

[28]  J. Downward,et al.  Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis , 2002, The Journal of Cell Biology.

[29]  J. Downward,et al.  Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. , 2002, The Journal of cell biology.

[30]  T. Seufferlein,et al.  Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. , 2001, Cancer research.

[31]  D. Birnbaum,et al.  ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor , 2000, Nature Cell Biology.

[32]  K. Guan,et al.  The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf. , 2000, Genes & development.

[33]  T. Haverty,et al.  Mechanisms of tubulointerstitial fibrosis , 2004, Current opinion in nephrology and hypertension.