On the function of object cells in the claustrum—key components in information processing in the visual system?

A recent paper by Jankowski and O'Mara (2015) throws new light on the function of the claustrum. These authors took recordings from 874 claustral neurons in unanesthetized behaving rats that showed responses probably anchored to visual stimuli. These fell into three categories—“place” neurons (38) that responded to the location of the rat, “boundary” neurons (23) that responded to boundaries closing the rat's environment, and “object” neurons (48) that fired only in response to the existence of a specific object in the environment. All three types of response showed with good within-session stability. Of particular interest in the present context are the object cells. These code the position in space of an object in the environment and not its particular properties (e.g., shape, texture, color). They also follow an object when it moves in the environment. Some object neurons can follow multiple objects (up to 3). Object neurons are also found in the subiculum, and in the anterior entorhinal, perirhinal, and anterior cingulate cortices with which areas the claustrum has extensive connections.

[1]  S. Zeki,et al.  The brain's specialized systems for aesthetic and perceptual judgment , 2013, The European journal of neuroscience.

[2]  Christoph Kayser,et al.  The Claustrum and the Orchestra of Cognitive Control , 2012 .

[3]  Z. Pylyshyn Visual indexes, preconceptual objects, and situated vision , 2001, Cognition.

[4]  R. Shapley,et al.  Is Gamma-Band Activity in the Local Field Potential of V1 Cortex a “Clock” or Filtered Noise? , 2011, The Journal of Neuroscience.

[5]  Claustrum: a case for directional, excitatory, intrinsic connectivity in the rat , 2015, The Journal of Physiological Sciences.

[6]  L. Shah,et al.  Functional magnetic resonance imaging. , 2010, Seminars in roentgenology.

[7]  C. Koch,et al.  What is the function of the claustrum? , 2005, Philosophical Transactions of the Royal Society B: Biological Sciences.

[8]  E. Garcia-Rill,et al.  Gamma Band Activity , 2015 .

[9]  J. Baizer,et al.  Comparative organization of the claustrum: what does structure tell us about function? , 2014, Front. Syst. Neurosci..

[10]  Maciej M. Jankowski,et al.  Dynamics of place, boundary and object encoding in rat anterior claustrum , 2015, Front. Behav. Neurosci..

[11]  Mikko Sams,et al.  Cortical operational synchrony during audio–visual speech integration , 2003, Brain and Language.

[12]  M. Molinari,et al.  The organization of the ipsi- and contralateral claustrocortical system in rat with notes on the bilateral claustrocortical projections in cat , 1985, Neuroscience.

[13]  M. E. Corcoran,et al.  Susceptibility to Kindling and Neuronal Connections of the Anterior Claustrum , 2001, The Journal of Neuroscience.

[14]  Lawrence Edelstein,et al.  Hypotheses relating to the function of the claustrum , 2012, Front. Integr. Neurosci..

[15]  E. Bullmore,et al.  Functional magnetic resonance imaging of synesthesia : activation of V 4 / V 8 by spoken words , 2002 .

[16]  Morgan D. Barense,et al.  Conjunctive Coding of Complex Object Features. , 2016, Cerebral cortex.

[17]  V. Ramachandran,et al.  The claustrum : structural, functional, and clinical neuroscience , 2014 .

[18]  Andrei Irimia,et al.  The DTI connectivity of the human claustrum , 2015, Human brain mapping.

[19]  J. Roll,et al.  Proprio-tactile integration for kinesthetic perception: An fMRI study , 2008, Neuropsychologia.

[20]  E. T. Bullmore,et al.  Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words , 2002, Nature Neuroscience.

[21]  S. Zeki A massively asynchronous, parallel brain , 2015, Philosophical Transactions of the Royal Society B: Biological Sciences.