论文信息 - Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain. - 字舞流文

Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain.

G. Gintant | R. Gum | T. Neelands | P. Kym | M. Kort | Xufeng Zhang | S. McGaraughty | H. M. Peltier | M. Pai | T. Hudzik | G. Lundgaard | N. Ghoreishi-Haack | D. DeGoey | J. R. Koenig | M. Matulenko | Cenchen Zhan | Meagan M. Fricano | O. El-Kouhen | Meena V Patel | R. Martin | Jun-Wei Xu | Daniel A. J. Bow | Marc J. C. Scanio | J. C. Kalvass