Nonprotonophoric Electrogenic Cl− Transport Mediated by Valinomycin-like Carriers

[1]  F. Ciruela,et al.  Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells. , 2015, Journal of the American Chemical Society.

[2]  S. Hussain,et al.  Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia , 2015, Nature Chemistry.

[3]  A. P. Davis,et al.  Biotin[6]uril Esters: Chloride-Selective Transmembrane Anion Carriers Employing C-H···Anion Interactions. , 2015, Journal of the American Chemical Society.

[4]  Sofya Kostina Berezin.  Valinomycin as a Classical Anionophore: Mechanism and Ion Selectivity , 2015, The Journal of Membrane Biology.

[5]  Philip A. Gale,et al.  Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells. , 2014, Nature chemistry.

[6]  S. Hussain,et al.  Preorganized bis-thioureas as powerful anion carriers: chloride transport by single molecules in large unilamellar vesicles. , 2014, Journal of the American Chemical Society.

[7]  Philip A. Gale,et al.  Thiosquaramides: pH switchable anion transporters. , 2014, Chemical science.

[8]  Sofya Kostina Berezin.  Synthetic Anionophores for Basic Anions as “Presumably, OH−/Cl− Antiporters”: From the Synthetic Ion Channels to Multi-ion Hopping, Anti-Hofmeister Selectivity, and Strong Positive AMFE , 2014, The Journal of Membrane Biology.

[9]  Philip A. Gale,et al.  Towards predictable transmembrane transport: QSAR analysis of anion binding and transport , 2013 .

[10]  Michael Grabe,et al.  A model of lysosomal pH regulation , 2013, The Journal of general physiology.

[11]  Sofya Kostina Berezin.  Theoretical modelling of anion transport in liposomes: electrogenic anion exchange as a new paradigm in supramolecular chemistry , 2013 .

[12]  Philip A. Gale,et al.  Chloride, carboxylate and carbonate transport by ortho-phenylenediamine-based bisureas , 2013 .

[13]  Philip A. Gale,et al.  Towards “drug-like” indole-based transmembrane anion transporters , 2012 .

[14]  S. Matile,et al.  Transmembrane anion transport mediated by halogen-bond donors , 2012, Nature Communications.

[15]  Philip A. Gale,et al.  Squaramides as potent transmembrane anion transporters. , 2012, Angewandte Chemie.

[16]  Fei Wang,et al.  A Synthetic Chloride Channel Restores Chloride Conductance in Human Cystic Fibrosis Epithelial Cells , 2012, PloS one.

[17]  P. Schreiner,et al.  (Thio)urea organocatalyst equilibrium acidities in DMSO. , 2012, Organic letters.

[18]  S. Matile,et al.  The Characterization of Synthetic Ion Channels and Pores , 2012 .

[19]  Zasha Weinberg,et al.  Widespread Genetic Switches and Toxicity Resistance Proteins for Fluoride , 2012, Science.

[20]  T. Torroba,et al.  Tambjamine alkaloids and related synthetic analogs: efficient transmembrane anion transporters. , 2012, Chemical communications.

[21]  Philip A. Gale,et al.  Structure–Activity Relationships in Tripodal Transmembrane Anion Transporters: The Effect of Fluorination , 2011, Journal of the American Chemical Society.

[22]  Stefan Matile,et al.  Recent synthetic transport systems. , 2011, Chemical Society reviews.

[23]  Sławomir Janusz Grabowski,et al.  What is the covalency of hydrogen bonding? , 2011, Chemical reviews.

[24]  Philip A. Gale,et al.  Structurally simple lipid bilayer transport agents for chloride and bicarbonate , 2011 .

[25]  Philip A. Gale,et al.  A dual host approach to transmembrane transport of salts. , 2011, Chemical communications.

[26]  Jeffery T. Davis,et al.  Recent advances in the transmembrane transport of anions. , 2010, Chemical Society reviews.

[27]  Philip A. Gale,et al.  Tripodal transmembrane transporters for bicarbonate. , 2010, Chemical communications.

[28]  A. P. Davis,et al.  From cholapod to cholaphane transmembrane anion carriers: accelerated transport through binding site enclosure. , 2010, Chemical communications.

[29]  Philip A. Gale,et al.  Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent. , 2010, Journal of the American Chemical Society.

[30]  Harry L Anderson,et al.  What is cooperativity? , 2009, Angewandte Chemie.

[31]  L. Pedersen,et al.  Estimation of molecular acidity via electrostatic potential at the nucleus and valence natural atomic orbitals. , 2009, The journal of physical chemistry. A.

[32]  Alan S. Verkman,et al.  Chloride channels as drug targets , 2009, Nature Reviews Drug Discovery.

[33]  Bradley D. Smith,et al.  Structure-activity relationships in cholapod anion carriers: enhanced transmembrane chloride transport through substituent tuning. , 2008, Chemistry.

[34]  Joseph A. Mindell,et al.  The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes , 2008, Nature.

[35]  W. M. Leevy,et al.  Recent Advances in Synthetic Membrane Transporters , 2007, Supramolecular chemistry.

[36]  David N Sheppard,et al.  Development of synthetic membrane transporters for anions. , 2007, Chemical Society reviews.

[37]  S. Matile,et al.  A simple method to identify supramolecules in action: Hill coefficients for exergonic self-assembly. , 2006, Chirality.

[38]  Jeffery T. Davis,et al.  Prodigiosin is a chloride carrier that can function as an anion exchanger. , 2005, Chemical communications.

[39]  Christopher Miller,et al.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels , 2004, Nature.

[40]  Bradley D. Smith,et al.  Chloride transport across vesicle and cell membranes by steroid-based receptors. , 2003, Angewandte Chemie.

[41]  Kaori Inoue,et al.  Influx of calcium and chloride ions into epidermal keratinocytes regulates exocytosis of epidermal lamellar bodies and skin permeability barrier homeostasis. , 2003, The Journal of investigative dermatology.

[42]  N. Demaurex.  pH Homeostasis of cellular organelles. , 2002, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

[43]  L. Galietta,et al.  Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists. , 2001, American journal of physiology. Cell physiology.

[44]  Frances M. Ashcroft,et al.  Ion channels and disease : channelopathies , 2000 .

[45]  T. Kataoka,et al.  Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport. , 1998, The Biochemical journal.

[46]  T. Kataoka,et al.  Prodigiosins as a New Group of H+/Cl−Symporters That Uncouple Proton Translocators* , 1998, The Journal of Biological Chemistry.

[47]  L. Weiss,et al.  Rigid Rod-Shaped Polyols: Functional Nonpeptide Models for Transmembrane Proton Channels† , 1997 .

[48]  J. Cuppoletti,et al.  Metalloporphyrin chloride ionophores: induction of increased anion permeability in lung epithelial cells. , 1996, The American journal of physiology.

[49]  M. Yamasaki,et al.  Prodigiosin 25‐C uncouples vacuolar type H+‐ATPase, inhibits vacuolar acidification and affects glycoprotein processing , 1995, FEBS letters.

[50]  M. Welsh,et al.  Expression of cystic fibrosis transmembrane conductance regulator in a model epithelium. , 1994, The American journal of physiology.

[51]  Yizhak Marcus,et al.  Thermodynamics of solvation of ions. Part 5.—Gibbs free energy of hydration at 298.15 K , 1991 .

[52]  H. Mollenhauer,et al.  Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity , 1990, Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes.

[53]  J. Gutknecht.  Proton/hydroxide conductance and permeability through phospholipid bilayer membranes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[54]  S. Balaz,et al.  Acidobasicity, reactivity, lipophilicity, and ability of phenylhydrazonopropanedinitriles to disturb the membrane potential , 1987 .

[55]  P. Läuger.  Mechanisms of Biological Ion Transport — Carriers, Channels, and Pumps in Artificial Lipid Membranes , 1985 .

[56]  J. Dilger,et al.  Transport of protons across membranes by weak acids. , 1980, Physiological reviews.

[57]  Derek W. Smith.  Ionic hydration enthalpies , 1977 .

[58]  B. Pressman,et al.  Biological applications of ionophores. , 1976, Annual review of biochemistry.

[59]  P. Läuger.  Carrier-mediated ion transport. , 1972, Science.

[60]  E A Liberman,et al.  Conversion of biomembrane-produced energy into electric form. II. Intact mitochondria. , 1970, Biochimica et biophysica acta.

[61]  P. Henderson,et al.  The action of certain antibiotics on mitochondrial, erythrocyte and artificial phospholipid membranes. The role of induced proton permeability. , 1969, The Biochemical journal.

[62]  E. Carafoli,et al.  The effect of dinitrophenol on the permeability of the mitochondrial membrane. , 1967, Biochemical and biophysical research communications.

[63]  P. Mitchell.  CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION , 1966, Biological reviews of the Cambridge Philosophical Society.

[64]  W. Prichard,et al.  A new class of uncoupling agents--carbonyl cyanide phenylhydrazones. , 1962, Biochemical and biophysical research communications.