Gene targeting reveals a hierarchy of transcription factors regulating specification of lymphoid cell fates.

[1]  D. Schatz,et al.  Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement. , 1995, Immunity.

[2]  R. Grosschedl,et al.  Failure of B-cell differentiation in mice lacking the transcription factor EBF , 1995, Nature.

[3]  K. Dorshkind Transcriptional control points during lymphopoiesis , 1994, Cell.

[4]  E. Wagner,et al.  Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5 BSAP , 1994, Cell.

[5]  H. Weintraub,et al.  The helix-loop-helix gene E2A is required for B cell formation , 1994, Cell.

[6]  Ian Krop,et al.  E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements , 1994, Cell.

[7]  A. Sharpe,et al.  The ikaros gene is required for the development of all lymphoid lineages , 1994, Cell.

[8]  E. Scott,et al.  Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. , 1994, Science.

[9]  J R Matthews,et al.  Structure and function of helix-loop-helix proteins. , 1994, Biochimica et biophysica acta.

[10]  M. Klemsz,et al.  Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1. , 1993, Blood.

[11]  A. Zlotnik,et al.  Control points in early T-cell development. , 1993, Immunology today.

[12]  M. K. Shin,et al.  Ets-related protein PU.1 regulates expression of the immunoglobulin J-chain gene through a novel Ets-binding element. , 1993, Genes & development.

[13]  U. Storb,et al.  PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer , 1993, Molecular and cellular biology.

[14]  B. Erman,et al.  Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins. , 1993, Science.

[15]  C. Murre,et al.  E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins , 1993, Molecular and cellular biology.

[16]  C. Turck,et al.  Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. , 1993, Genes & development.

[17]  J. Samaridis,et al.  Bone marrow clones representing an intermediate stage of development between hematopoietic stem cells and pro-T-lymphocyte or pro-B- lymphocyte progenitors , 1993 .

[18]  D. Moore,et al.  Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. , 1992, Science.

[19]  R. Grosschedl,et al.  An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[20]  A. Aguzzi,et al.  Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. , 1992, Genes & development.

[21]  M. Busslinger,et al.  The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP , 1992, Molecular and cellular biology.

[22]  B. Birshtein,et al.  A nuclear DNA-binding protein expressed during early stages of B cell differentiation interacts with diverse segments within and 3' of the Ig H chain gene cluster. , 1992, Journal of immunology.

[23]  A. Cumano,et al.  Bipotential precursors of B cells and macrophages in murine fetal liver , 1992, Nature.

[24]  V. Stewart,et al.  RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement , 1992, Cell.

[25]  Susumu Tonegawa,et al.  RAG-1-deficient mice have no mature B and T lymphocytes , 1992, Cell.

[26]  H. Singh,et al.  BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1 , 1992, Molecular and cellular biology.

[27]  A. Kudo,et al.  A pre‐B‐ and B cell‐specific DNA‐binding protein, EBB‐1, which binds to the promoter of the VpreB1 gene , 1992, European journal of immunology.

[28]  M. Klemsz,et al.  PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity , 1992, Molecular and cellular biology.

[29]  R. Grosschedl,et al.  A novel lineage‐specific nuclear factor regulates mb‐1 gene transcription at the early stages of B cell differentiation. , 1991, The EMBO journal.

[30]  A. Rolink,et al.  Molecular and cellular origins of B lymphocyte diversity , 1991, Cell.

[31]  David Baltimore,et al.  Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo , 1991, Cell.

[32]  S. Swerdlow,et al.  A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis , 1991, Cell.

[33]  J D Kemp,et al.  Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow , 1991, The Journal of experimental medicine.

[34]  M. Goebl The PU.1 transcription factor is the product of the putative oncogene Spi-1 , 1990, Cell.

[35]  A. Barberis,et al.  A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation. , 1990, Genes & development.

[36]  M. Klemsz,et al.  The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene , 1990, Cell.

[37]  David Baltimore,et al.  A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins , 1989, Cell.

[38]  F. Moreau-Gachelin,et al.  Spi-1 is a putative oncogene in virally induced murine erythroleukaemias , 1988, Nature.

[39]  C. Bunce,et al.  Stochastic or ordered lineage commitment during hemopoiesis? , 1987, Leukemia.

[40]  T. Mak,et al.  Lymphocyte ontogeny and activation in gene targeted mutant mice. , 1994, Annual review of immunology.