Enzymatic biodiesel production: an overview of potential feedstocks and process development.

The increased global demand for biofuels has prompted the search for alternatives to edible oils for biodiesel production. Given the abundance and cost, waste and nonedible oils have been investigated as potential feedstocks. A recent research interest is the conversion of such feedstocks into biodiesel via enzymatic processes, which have considerable advantages over conventional alkali-catalyzed processes. To expand the viability of enzymatic biodiesel production, considerable effort has been directed toward process development in terms of biodiesel productivity, application to wide ranges of contents of water and fatty acids, adding value to glycerol byproducts, and bioreactor design. A cost evaluation suggested that, with the current enzyme prices, the cost of catalysts alone is not competitive against that of alkalis. However, it can also be expected that further process optimization will lead to a reduced cost in enzyme preparation as well as in downstream processes.

[1]  Yomi Watanabe,et al.  Conversion of degummed soybean oil to biodiesel fuel with immobilized Candida antarctica lipase , 2002 .

[2]  Hao Shi,et al.  Enzymatic production of biodiesel from Pistacia chinensis bge seed oil using immobilized lipase , 2012 .

[3]  P. Bisen,et al.  Biodiesel production with special emphasis on lipase-catalyzed transesterification , 2010, Biotechnology Letters.

[4]  M. Sharma,et al.  Jatropha-Palm biodiesel blends: An optimum mix for Asia , 2007 .

[5]  Dehua Liu,et al.  Comparative study on lipase-catalyzed transformation of soybean oil for biodiesel production with different acyl acceptors , 2004 .

[6]  Wei Li,et al.  Perspectives for biotechnological production of biodiesel and impacts , 2008, Applied Microbiology and Biotechnology.

[7]  Jo-Shu Chang,et al.  Enzymatic transesterification of microalgal oil from Chlorella vulgaris ESP-31 for biodiesel synthesis using immobilized Burkholderia lipase. , 2012, Bioresource technology.

[8]  Qingyu Wu,et al.  Large‐scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors , 2007, Biotechnology and bioengineering.

[9]  A. McAloon,et al.  A process model to estimate biodiesel production costs. , 2006, Bioresource technology.

[10]  Duane T. Johnson,et al.  The glycerin glut: Options for the value‐added conversion of crude glycerol resulting from biodiesel production , 2007 .

[11]  Yomi Watanabe,et al.  Production of FAME from acid oil model using immobilized Candida antarctica lipase , 2005 .

[12]  Y. Yücel,et al.  Biodiesel production from pomace oil by using lipase immobilized onto olive pomace. , 2011, Bioresource technology.

[13]  M. Talukder,et al.  Two-step lipase catalysis for production of biodiesel , 2010 .

[14]  M. Talukder,et al.  Conversion of Waste Cooking Oil to Biodiesel via Enzymatic Hydrolysis Followed by Chemical Esterification , 2010 .

[15]  Rainer Kalscheuer,et al.  Microdiesel: Escherichia coli engineered for fuel production. , 2006, Microbiology.

[16]  A. Kondo,et al.  Enzymatic packed-bed reactor integrated with glycerol-separating system for solvent-free production of biodiesel fuel , 2011 .

[17]  Pu Peng,et al.  Combination of two lipases more efficiently catalyzes methanolysis of soybean oil for biodiesel production in aqueous medium , 2010 .

[18]  Seiji Kojima,et al.  Lipase-catalyzed biodiesel production from waste activated bleaching earth as raw material in a pilot plant. , 2008, Bioresource technology.

[19]  Wen‐Teng Wu,et al.  An enzymatic/acid-catalyzed hybrid process for biodiesel production from soybean oil , 2008 .

[20]  G. Baker,et al.  New eutectic ionic liquids for lipase activation and enzymatic preparation of biodiesel. , 2011, Organic & biomolecular chemistry.

[21]  Débora Oliveira,et al.  Optimization of enzymatic production of biodiesel from castor oil in organic solvent medium , 2004, Applied biochemistry and biotechnology.

[22]  K. Kawakami,et al.  Application of a Burkholderia cepacia lipase-immobilized silica monolith to batch and continuous biodiesel production with a stoichiometric mixture of methanol and crude Jatropha oil , 2011, Biotechnology for biofuels.

[23]  Mustafa Balat,et al.  Potential alternatives to edible oils for biodiesel production - A review of current work , 2011 .

[24]  Jing-Qi Lai,et al.  Enzymatic production of microalgal biodiesel in ionic liquid [BMIm][PF6] , 2012 .

[25]  Uwe T. Bornscheuer,et al.  The application of biotechnological methods for the synthesis of biodiesel , 2009 .

[26]  Pär Tufvesson,et al.  Towards a cost-effective immobilized lipase for the synthesis of specialty chemicals , 2011 .

[27]  Jing-Qi Lai,et al.  Penicillium expansum lipase-catalyzed production of biodiesel in ionic liquids. , 2011, Bioresource technology.

[28]  Sung Ok Han,et al.  Biodiesel production by a mixture of Candida rugosa and Rhizopus oryzae lipases using a supercritical carbon dioxide process. , 2011, Bioresource technology.

[29]  Joaquim M S Cabral,et al.  Performance of a cutinase membrane reactor for the production of biodiesel in organic media , 2011, Biotechnology and bioengineering.

[30]  A. Kondo,et al.  Production of biodiesel fuel from soybean oil catalyzed by fungus whole-cell biocatalysts in ionic liquids , 2010 .

[31]  Vitor Hugo Moreau,et al.  One-step enzymatic production of fatty acid ethyl ester from high-acidity waste feedstocks in solvent-free media. , 2011, Bioresource technology.

[32]  Ben-Guang Rong,et al.  Process simulation and economical evaluation of enzymatic biodiesel production plant. , 2010, Bioresource technology.

[33]  Hideo Noda,et al.  Biodiesel-fuel production in a packed-bed reactor using lipase-producing Rhizopus oryzae cells immobilized within biomass support particles. , 2007 .

[34]  Li Wang,et al.  Lipase-catalyzed biodiesel production from soybean oil deodorizer distillate with absorbent present in tert-butanol system , 2006 .

[35]  Yomi Watanabe,et al.  Continuous production of biodiesel fuel from vegetable oil using immobilized Candida antarctica lipase , 2000 .

[36]  M. Talukder,et al.  Improved Method for Efficient Production of Biodiesel from Palm Oil , 2008 .

[37]  Chang Zheng,et al.  RETRACTED: Biodiesel production using magnetically stabilized fluidized bed reactor , 2012 .

[38]  A. Ahmad,et al.  Microalgae as a sustainable energy source for biodiesel production: A review , 2011 .

[39]  Xuebing Zhao,et al.  Effects of some inhibitors on the growth and lipid accumulation of oleaginous yeast Rhodosporidium toruloides and preparation of biodiesel by enzymatic transesterification of the lipid , 2012, Bioprocess and Biosystems Engineering.

[40]  J. Iborra,et al.  A recyclable enzymatic biodiesel production process in ionic liquids. , 2011, Bioresource technology.

[41]  Tadeusz Antczak,et al.  Enzymatic biodiesel synthesis – Key factors affecting efficiency of the process , 2009 .

[42]  Zhi Wang,et al.  Both hydrolytic and transesterification activities of Penicillium expansum lipase are significantly enhanced in ionic liquid [BMIm][PF6] , 2010 .

[43]  Birgir Norddahl,et al.  A review of the current state of biodiesel production using enzymatic transesterification , 2009, Biotechnology and bioengineering.

[44]  Fei Wang,et al.  Expression and characterization of recombinant Rhizopus oryzae lipase for enzymatic biodiesel production. , 2011, Bioresource technology.

[45]  Kenthorai Raman Jegannathan,et al.  Economic assessment of biodiesel production: Comparison of alkali and biocatalyst processes , 2011 .

[46]  Man Kee Lam,et al.  Homogeneous, heterogeneous and enzymatic catalysis for transesterification of high free fatty acid oil (waste cooking oil) to biodiesel: a review. , 2010, Biotechnology advances.

[47]  E. Park,et al.  Enhancement of lipase catalyzed-fatty acid methyl esters production from waste activated bleaching earth by nullification of lipase inhibitors. , 2009, Bioresource technology.

[48]  A. Kondo,et al.  Process engineering and optimization of glycerol separation in a packed-bed reactor for enzymatic biodiesel production. , 2011, Bioresource technology.

[49]  Sung Ho Ha,et al.  Lipase-catalyzed biodiesel production from soybean oil in ionic liquids. , 2007 .

[50]  Mo Xian,et al.  Biodiesel production from oleaginous microorganisms , 2009 .

[51]  Rodrigo Navia,et al.  Biotechnological processes for biodiesel production using alternative oils , 2010, Applied Microbiology and Biotechnology.

[52]  A. Kondo,et al.  Development of an Aspergillus oryzae whole-cell biocatalyst coexpressing triglyceride and partial glyceride lipases for biodiesel production. , 2011, Bioresource technology.

[53]  M. Zong,et al.  HIGHLY EFFICIENT TRANSFORMATION OF WASTE OIL TO BIODIESEL BY IMMOBILIZED LIPASE FROM PENICILLIUM EXPANSUM , 2009 .

[54]  S. W. Kim,et al.  Biodiesel Production from Various Oils Under Supercritical Fluid Conditions by Candida antartica Lipase B Using a Stepwise Reaction Method , 2009, Applied biochemistry and biotechnology.

[55]  V. Balcão,et al.  Bioreactors with immobilized lipases: state of the art. , 1996, Enzyme and microbial technology.

[56]  Yanjun Jiang,et al.  Reactive extraction and in situ self-catalyzed methanolysis of germinated oilseed for biodiesel production , 2011 .

[57]  A. Kondo,et al.  Improved performance of a packed-bed reactor for biodiesel production through whole-cell biocatalysis employing a high-lipase-expression system , 2012 .

[58]  Duk-Ki Kim,et al.  Enzymatic coproduction of biodiesel and glycerol carbonate from soybean oil and dimethyl carbonate. , 2011, Enzyme and microbial technology.

[59]  Rodrigo Navia,et al.  Improving fatty acid methyl ester production yield in a lipase-catalyzed process using waste frying oils as feedstock. , 2010, Journal of bioscience and bioengineering.

[60]  Z. Xiu,et al.  A combined bioprocess of biodiesel production by lipase with microbial production of 1,3-propanediol by Klebsiella pneumoniae , 2008 .

[61]  A. Kondo,et al.  Biodiesel fuel production by transesterification of oils. , 2001, Journal of bioscience and bioengineering.

[62]  Norashid Aziz,et al.  Solid heterogeneous catalysts for transesterification of triglycerides with methanol: A review , 2009 .

[63]  Yomi Watanabe,et al.  Enzymatic Production of Fatty Acid Methyl Esters by Hydrolysis of Acid Oil Followed by Esterification , 2007 .

[64]  P. M. Nielsen,et al.  Combining Enzymatic Esterification with Conventional Alkaline Transesterification in an Integrated Biodiesel Process , 2011, Applied biochemistry and biotechnology.

[65]  Warawut Chulalaksananukul,et al.  Potential plant oil feedstock for lipase-catalyzed biodiesel production in Thailand , 2008 .

[66]  A. Kondo,et al.  Enzymatic production of biodiesel from Jatropha oil : A comparative study of immobilized-whole cell and commercial lipases as a biocatalyst , 2008 .

[67]  J. Woodley,et al.  Guidelines and Cost Analysis for Catalyst Production in Biocatalytic Processes , 2011 .

[68]  Wei Li,et al.  Rhizopus oryzae IFO 4697 whole cell-catalyzed methanolysis of crude and acidified rapeseed oils for biodiesel production in tert-butanol system , 2007 .

[69]  Luiz Augusto Horta Nogueira,et al.  Does biodiesel make sense , 2011 .

[70]  Meisam Tabatabaei,et al.  Upstream and downstream strategies to economize biodiesel production. , 2011, Bioresource technology.

[71]  B. Zhang,et al.  Enzyme immobilization for biodiesel production , 2011, Applied Microbiology and Biotechnology.

[72]  D. Freire,et al.  Application of lipase from the physic nut (Jatropha curcas L.) to a new hybrid (enzyme/chemical) hydroesterification process for biodiesel production , 2010 .

[73]  A. Kondo,et al.  Use of mono-and diacylglycerol lipase as immobilized fungal whole cells to convert residual partial glycerides enzymatically into fatty acid methyl esters , 2009 .

[74]  H. Fukuda,et al.  Whole-cell biocatalysts for biodiesel fuel production. , 2008, Trends in biotechnology.

[75]  Hideo Noda,et al.  Conversion of vegetable oil to biodiesel using immobilized Candida antarctica lipase , 1999 .