Atopic dermatitis: Correlation of distinct risk factors with age of onset in adulthood compared to childhood

Atopic dermatitis (AD) has long been regarded as a primarily pediatric disease. However, there is growing evidence for a high rate of adult‐onset AD. We aimed to characterize factors associated with adult‐onset versus childhood‐onset AD and controls.

[1]  K. Thomas,et al.  Clinical examination for hyperlinear palms to determine filaggrin genotype: A diagnostic test accuracy study , 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[2]  C. Rhee,et al.  Associations of clinical, psychological, and socioeconomic characteristics with nicotine dependence in smokers , 2021, Scientific Reports.

[3]  T. Bieber,et al.  JAK1/2 inhibition impairs the development and function of inflammatory dendritic epidermal cells in atopic dermatitis. , 2020, The Journal of allergy and clinical immunology.

[4]  A. Qureshi,et al.  Smoking and risk of adult-onset atopic dermatitis in US women. , 2020, Journal of the American Academy of Dermatology.

[5]  Jinhua Xu,et al.  Distinct clinical features and serum cytokine pattern of elderly atopic dermatitis in China , 2020, Journal of the European Academy of Dermatology and Venereology : JEADV.

[6]  C. Akdis,et al.  Unraveling the complexity of atopic dermatitis: The CK‐CARE approach toward precision medicine , 2020, Allergy.

[7]  A. Neumann,et al.  The skin microbiome as a clinical biomarker in atopic eczema: Promises, navigation, and pitfalls. , 2020, The Journal of allergy and clinical immunology.

[8]  D. Margolis,et al.  Longitudinal atopic dermatitis control and persistence vary with timing of disease onset in children: a cohort study. , 2019, Journal of the American Academy of Dermatology.

[9]  Y. Tokura,et al.  Palmar hyperlinearity in early childhood atopic dermatitis is associated with filaggrin mutation and sensitization to egg , 2019, Pediatric dermatology.

[10]  L. Naldi,et al.  Atopic dermatitis in young adult italian males: persistent and adult-onset varieties did not differ clinically and as for allergological variables. , 2019, Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia.

[11]  A. Paller,et al.  The atopic march and atopic multimorbidity: Many trajectories, many pathways , 2019, The Journal of allergy and clinical immunology.

[12]  L. Smeeth,et al.  Severe and predominantly active atopic eczema in adulthood and long term risk of cardiovascular disease: population based cohort study , 2018, British Medical Journal.

[13]  S. Langan,et al.  The prevalence of atopic dermatitis beyond childhood: A systematic review and meta‐analysis of longitudinal studies , 2017, Allergy.

[14]  J. Silverberg,et al.  Phenotypical Differences of Childhood- and Adult-Onset Atopic Dermatitis. , 2017, The journal of allergy and clinical immunology. In practice.

[15]  David M. Evans,et al.  Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts , 2017, Pediatrics.

[16]  D. Margolis,et al.  The Long-Term Course of Atopic Dermatitis. , 2017, Dermatologic clinics.

[17]  M. Ege,et al.  Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood , 2017, JAMA pediatrics.

[18]  D. Margolis,et al.  Patterns and predictors of atopic dermatitis disease control past childhood: An observational cohort study. , 2017, The Journal of allergy and clinical immunology.

[19]  B. Chung,et al.  Clinical Features of Atopic Dermatitis in Adults Are Different according to Onset , 2017, Journal of Korean medical science.

[20]  J. Silverberg,et al.  Association of atopic dermatitis with smoking: A systematic review and meta-analysis. , 2016, Journal of the American Academy of Dermatology.

[21]  J. Silverberg,et al.  Associations of Physical Activity and Sedentary Behavior with Atopic Disease in United States Children. , 2016, The Journal of pediatrics.

[22]  S. Nutten Atopic Dermatitis: Global Epidemiology and Risk Factors , 2015, Annals of Nutrition and Metabolism.

[23]  J. Silverberg Persistence of childhood eczema into adulthood. , 2014, JAMA dermatology.

[24]  D. Margolis,et al.  Persistence of mild to moderate atopic dermatitis. , 2014, JAMA dermatology.

[25]  K. Nordlind,et al.  Adult atopic dermatitis patients and physical exercise: a Swedish questionnaire study. , 2014, Acta dermato-venereologica.

[26]  Gary Evans,et al.  Exploratory Multivariate Analysis by Example Using R , 2011 .

[27]  Y. Ko,et al.  Lifetime exposure to cigarette smoking and the development of adult‐onset atopic dermatitis , 2011, The British journal of dermatology.

[28]  Sanford Weisberg,et al.  An R Companion to Applied Regression , 2010 .

[29]  M. Sopori,et al.  Effects of cigarette smoke on the immune system , 2002, Nature Reviews Immunology.

[30]  J. Krueger,et al.  Atopic dermatitis endotypes and implications for targeted therapeutics. , 2019, The Journal of allergy and clinical immunology.

[31]  O. Hornstein,et al.  Evaluation and relevance of atopic basic and minor features in patients with atopic dermatitis and in the general population. , 1989, Acta dermato-venereologica. Supplementum.