MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

[1]  M. Siegmann,et al.  Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[2]  M. Šuša,et al.  Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[3]  J. Blenis,et al.  Identification of Xenopus S6 protein kinase homologs (pp90rsk) in somatic cells: phosphorylation and activation during initiation of cell proliferation , 1990, Molecular and cellular biology.

[4]  D. Alcorta,et al.  Two distinct enzymes contribute to biphasic S6 phosphorylation in serum-stimulated chicken embryo fibroblasts , 1990, Molecular and cellular biology.

[5]  J. Maller,et al.  Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase , 1990, Nature.

[6]  M. Siegmann,et al.  A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells. , 1989, The EMBO journal.

[7]  M. Cobb,et al.  An insulin-stimulated ribosomal protein S6 kinase from rabbit liver. , 1989, The Journal of biological chemistry.

[8]  J. Maller,et al.  In vivo phosphorylation and activation of ribosomal protein S6 kinases during Xenopus oocyte maturation. , 1989, The Journal of biological chemistry.

[9]  J. Avruch,et al.  Purification of a hepatic S6 kinase from cycloheximide-treated Rats. , 1989, The Journal of biological chemistry.

[10]  D. Fabbro,et al.  EGF induces biphasic S6 kinase activation: Late phase is protein kinase C-dependent and contributes to mitogenicity , 1989, Cell.

[11]  M. Siegmann,et al.  Purification and characterization of a 40 S ribosomal protein S6 kinase from vanadate-stimulated Swiss 3T3 cells. , 1989, The Journal of biological chemistry.

[12]  M. Siegmann,et al.  S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[13]  T. Sturgill,et al.  Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells. , 1988, The Journal of biological chemistry.

[14]  J. Maller,et al.  Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II , 1988, Nature.

[15]  G. Thomas,et al.  Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: insulin activation of type 1 phosphatase. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[16]  T. Sturgill,et al.  Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[17]  J. Blenis,et al.  A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[18]  E. Nishida,et al.  Activation of a Ca2+-inhibitable protein kinase that phosphorylates microtubule-associated protein 2 in vitro by growth factors, phorbol esters, and serum in quiescent cultured human fibroblasts. , 1988, The Journal of biological chemistry.

[19]  T. Sturgill,et al.  Insulin-stimulated microtubule associated protein kinase is detectable by analytical gel chromatography as a 35-kDa protein in myocytes, adipocytes, and hepatocytes. , 1988, Archives of biochemistry and biophysics.

[20]  G. Thomas,et al.  Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells. , 1988, The Journal of biological chemistry.

[21]  G. Thomas,et al.  Identification and characterization of a mitogen-activated S6 kinase. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[22]  J. Blenis,et al.  Identification of a ribosomal protein S6 kinase regulated by transformation and growth-promoting stimuli. , 1987, The Journal of biological chemistry.

[23]  T. Sturgill,et al.  Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[24]  J. Maller,et al.  Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6. , 1986, The Journal of biological chemistry.

[25]  J. Blenis,et al.  Phorbol ester, serum, and rous sarcoma virus transforming gene product induce similar phosphorylations of ribosomal protein S6. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[26]  M. Siegmann,et al.  The effect of serum, EGF, PGF2α and insulin on S6 phosphorylation and the initiation of protein and DNA synthesis , 1982, Cell.

[27]  R. Brooks.  Continuous protein synthesis is required to maintain the probability of entry into S phase , 1977, Cell.