论文信息 - Productive Ascites Growth of Heterohybridomas between Epstein‐Barr Virus‐Transformed Human B Cells and Murine P3×63Ag8.653 Myeloma Cells

Productive Ascites Growth of Heterohybridomas between Epstein‐Barr Virus‐Transformed Human B Cells and Murine P3×63Ag8.653 Myeloma Cells

Heterohybridomas between Epstein‐Barr virus‐transformed human B cells and murine myeloma P3×63Ag8.653 cells were found to produce sizable quantities of human monoclonal antibodies in nude mouse ascites. Mice injected intraperitoneally with two of such heterohybridomas yielded several milliliters of ascites fluid which contained nearly 100‐fold higher anti‐platelet activities than those in routine culture supernatants.

M. Matsumoto | Yuzuru Kobayashi | Kenichi Mochizuki

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