Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries
暂无分享,去创建一个
Thomas R. Ioerger | James C. Sacchettini | Michael A. DeJesus | Christopher M. Sassetti | Yanjia J. Zhang | Eric J. Rubin | J. Sacchettini | T. Ioerger | E. Rubin | C. Sassetti | M. DeJesus | Y. J. Zhang
[1] Joel S. Freundlich,et al. Supplemental Information Structure-Guided Discovery of Phenyl-diketo Acids as Potent Inhibitors of M . tuberculosis Malate Synthase , 2012 .
[2] Eduardo Abeliuk,et al. The essential genome of a bacterium , 2011, Molecular systems biology.
[3] Sayera Banu,et al. Are the PE‐PGRS proteins of Mycobacterium tuberculosis variable surface antigens? , 2002, Molecular microbiology.
[4] B. Barrell,et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence , 1998, Nature.
[5] K. Broman,et al. Estimating the number of essential genes in a genome by random transposon mutagenesis , 2002 .
[6] W. Bishai,et al. Designer Arrays for Defined Mutant Analysis To Detect Genes Essential for Survival of Mycobacterium tuberculosis in Mouse Lungs , 2005, Infection and Immunity.
[7] Aldert L. Zomer,et al. ESSENTIALS: Software for Rapid Analysis of High Throughput Transposon Insertion Sequencing Data , 2012, PloS one.
[8] D. Schnappinger,et al. The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo , 2011, Tuberculosis.
[9] Ranjeet Singh,et al. Phosphorylation of PhoP Protein Plays Direct Regulatory Role in Lipid Biosynthesis of Mycobacterium tuberculosis* , 2011, The Journal of Biological Chemistry.
[10] T. Parish,et al. The role of GlnD in ammonia assimilation in Mycobacterium tuberculosis , 2007, Tuberculosis.
[11] Samiul Hasan,et al. Prioritizing Genomic Drug Targets in Pathogens: Application to Mycobacterium tuberculosis , 2006, PLoS Comput. Biol..
[12] G. Kaplan,et al. The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro , 2007, Molecular microbiology.
[13] Thomas R. Ioerger,et al. Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis , 2012, PLoS pathogens.
[14] L. Holm,et al. The Pfam protein families database , 2005, Nucleic Acids Res..
[15] Stephen H. Bryant,et al. Domain size distributions can predict domain boundaries , 2000, Bioinform..
[16] Thomas R. Ioerger,et al. High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism , 2011, PLoS pathogens.
[17] C. Gee,et al. A Phosphorylated Pseudokinase Complex Controls Cell Wall Synthesis in Mycobacteria , 2012, Science Signaling.
[18] Karl W. Broman,et al. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[19] J. Mekalanos,et al. In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[20] Mark Schilling,et al. The Longest Run of Heads , 1990 .
[21] Michael Hecker,et al. The progress made in determining the Mycobacterium tuberculosis structural proteome , 2011, Proteomics.
[22] S. Haydel,et al. The prrAB Two-Component System Is Essential for Mycobacterium tuberculosis Viability and Is Induced under Nitrogen-Limiting Conditions , 2011, Journal of bacteriology.
[23] M. Churchill,et al. A purified mariner transposase is sufficient to mediate transposition in vitro , 1996, The EMBO journal.
[24] J. Mekalanos,et al. Systematic identification of essential genes by in vitro mariner mutagenesis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[25] Christopher M. Sassetti,et al. Genetic requirements for mycobacterial survival during infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[26] James C. Sacchettini,et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase , 2000, Nature.
[27] D Botstein,et al. Functional Analysis of the Genes of Yeast Chromosome V by Genetic Footprinting , 1996, Science.
[28] Matthias Wilmanns,et al. The progress made in determining the Mycobacterium tuberculosis structural proteome , 2011, Proteomics.
[29] Kenneth Rice,et al. FDR and Bayesian Multiple Comparisons Rules , 2006 .
[30] Georgia Giannoukos,et al. Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung , 2009, Proceedings of the National Academy of Sciences.
[31] Robert D. Finn,et al. The Pfam protein families database , 2004, Nucleic Acids Res..
[32] Leopold Parts,et al. Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants. , 2009, Genome research.
[33] J. W. Campbell,et al. Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655 , 2003, Journal of bacteriology.
[34] K. E. Pullen,et al. An alternate conformation and a third metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr protein phosphatase. , 2004, Structure.
[35] Finbarr Hayes,et al. Transposon-based strategies for microbial functional genomics and proteomics. , 2003, Annual review of genetics.
[36] E. Rubin,et al. Genes required for mycobacterial growth defined by high density mutagenesis , 2003, Molecular microbiology.
[37] R. C. Fahey,et al. The mshA gene encoding the glycosyltransferase of mycothiol biosynthesis is essential in Mycobacterium tuberculosis Erdman. , 2006, FEMS microbiology letters.