NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs.
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G. Pan | R. Stewart | J. Thomson | Jessica Antosiewicz-Bourget | Junying Yu | S. Tian | R. Xu | Ruthann M Peck | Tori L. Sampsell-Barron | Feng Gu | S. Root | Shulan Tian
[1] H. Lehrach,et al. Fibroblast Growth Factor 2 Modulates Transforming Growth Factor β Signaling in Mouse Embryonic Fibroblasts and Human ESCs (hESCs) to Support hESC Self‐Renewal , 2007, Stem cells.
[2] Mitchell D. Probasco,et al. Feeder-independent culture of human embryonic stem cells , 2006, Nature Methods.
[3] Fred H. Gage,et al. Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells , 2006, Proceedings of the National Academy of Sciences.
[4] Xuan Yuan,et al. Activin A Maintains Self‐Renewal and Regulates Fibroblast Growth Factor, Wnt, and Bone Morphogenic Protein Pathways in Human Embryonic Stem Cells , 2006, Stem cells.
[5] Sheng Ding,et al. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[6] Megan F. Cole,et al. Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells , 2006, Cell.
[7] Yoav Mayshar,et al. Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features , 2006, Development.
[8] J. Thomson,et al. Basic Fibroblast Growth Factor Support of Human Embryonic Stem Cell Self‐Renewal , 2006, Stem cells.
[9] J. Thomson,et al. Derivation of human embryonic stem cells in defined conditions , 2006, Nature Biotechnology.
[10] R. Pedersen,et al. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells , 2005, Journal of Cell Science.
[11] Megan F. Cole,et al. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.
[12] E. Brunette,et al. Expansion of human embryonic stem cells in defined serum-free medium devoid of animal-derived products. , 2005, Biotechnology and bioengineering.
[13] Younghee Lee,et al. Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1. , 2005, Stem cells and development.
[14] L. Hyslop,et al. Downregulation of NANOG Induces Differentiation of Human Embryonic Stem Cells to Extraembryonic Lineages , 2005, Stem cells.
[15] P. Robson,et al. Transcriptional Regulation of Nanog by OCT4 and SOX2* , 2005, Journal of Biological Chemistry.
[16] Lisheng Wang,et al. Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. , 2005, Blood.
[17] Ana D. Lopez,et al. Activin A Maintains Pluripotency of Human Embryonic Stem Cells in the Absence of Feeder Layers , 2005, Stem cells.
[18] Ariel J. Levine,et al. TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells , 2005 .
[19] J. Thomson,et al. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells , 2005, Nature Methods.
[20] J. Lebkowski,et al. Basic Fibroblast Growth Factor Supports Undifferentiated Human Embryonic Stem Cell Growth Without Conditioned Medium , 2005, Stem cells.
[21] G. Daley,et al. High‐Efficiency RNA Interference in Human Embryonic Stem Cells , 2005, Stem cells.
[22] D. Besser. Expression of Nodal, Lefty-A, and Lefty-B in Undifferentiated Human Embryonic Stem Cells Requires Activation of Smad2/3* , 2004, Journal of Biological Chemistry.
[23] P. Andrews,et al. Specific Knockdown of Oct4 and β2‐microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells , 2004, Stem cells.
[24] J. Itskovitz‐Eldor,et al. Feeder Layer- and Serum-Free Culture of Human Embryonic Stem Cells1 , 2004, Biology of reproduction.
[25] C. Mummery,et al. Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin , 2004, Journal of Cell Science.
[26] T. Burdon,et al. Oct‐4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem Cells , 2004, Stem cells.
[27] P. Brown,et al. Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[28] J. Massagué,et al. Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.
[29] M. Murakami,et al. The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells , 2003, Cell.
[30] J. Nichols,et al. Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.
[31] J. Thomson,et al. High‐Level Sustained Transgene Expression in Human Embryonic Stem Cells Using Lentiviral Vectors , 2003, Stem cells.
[32] J. Thomson,et al. BMP4 initiates human embryonic stem cell differentiation to trophoblast , 2002, Nature Biotechnology.
[33] J. Massagué,et al. Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene* , 2002, The Journal of Biological Chemistry.
[34] Chunhui Xu,et al. Feeder-free growth of undifferentiated human embryonic stem cells , 2001, Nature Biotechnology.
[35] J A Thomson,et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. , 2000, Developmental biology.
[36] J. Massagué,et al. Transcriptional control by the TGF‐β/Smad signaling system , 2000 .
[37] H. Schöler,et al. Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 , 1998, Cell.
[38] Yigong Shi,et al. Crystal Structure of a Smad MH1 Domain Bound to DNA Insights on DNA Binding in TGF-β Signaling , 1998, Cell.
[39] Kirby D. Johnson,et al. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic , 1997, Nature.
[40] 黒田 貴雄. Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression , 2007 .
[41] Michael P. Snyder,et al. Defined culture conditions of human embryonic stem cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[42] Ariel J. Levine,et al. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. , 2005, Development.
[43] P. Greengard,et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor , 2004, Nature Medicine.
[44] J. Massagué,et al. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. , 2003, Cell.